Academic Journal
Generation and characterization of two iPSC lines INDBi002-A and INDBi002-B from human keratinocytes of a healthy female using Sendai Virus reprogramming.
| Τίτλος: | Generation and characterization of two iPSC lines INDBi002-A and INDBi002-B from human keratinocytes of a healthy female using Sendai Virus reprogramming. |
|---|---|
| Συγγραφείς: | Sperlich D; Institute of Neuroanatomy and Developmental Biology, University of Tuebingen, Germany., Becker K; Institute of Neuroanatomy and Developmental Biology, University of Tuebingen, Germany., Klingenstein S; Institute of Neuroanatomy and Developmental Biology, University of Tuebingen, Germany., Mau-Holzmann U; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Germany., Liebau S; Institute of Neuroanatomy and Developmental Biology, University of Tuebingen, Germany., Achberger K; Institute of Neuroanatomy and Developmental Biology, University of Tuebingen, Germany. Electronic address: kevin.achberger@uni-tuebingen.de. |
| Πηγή: | Stem cell research [Stem Cell Res] 2026 Sep; Vol. 95, pp. 104075. Date of Electronic Publication: 2026 Aug 11. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Country of Publication: England NLM ID: 101316957 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1876-7753 (Electronic) Linking ISSN: 18735061 NLM ISO Abbreviation: Stem Cell Res Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Kidlington, Oxford : Elsevier |
| Ιατρικοί όροι (MeSH): | Induced Pluripotent Stem Cells*/cytology , Induced Pluripotent Stem Cells*/metabolism , Keratinocytes*/cytology , Keratinocytes*/metabolism , Sendai virus*/genetics , Cellular Reprogramming*, Humans ; Female ; Cell Differentiation ; Cell Line |
| Περίληψη: | We established two fully characterized induced pluripotent stem cell (iPSC) lines from human keratinocytes via Sendai virus-mediated reprogramming. This non-integrating approach maintains genomic integrity, facilitating the generation of pluripotent cell lines with stable self-renewal and multilineage differentiation potential. Characterization confirmed the expression of stemness markers, the capacity for trilineage differentiation, and a normal karyotype. The iPSC lines are a valuable platform for applications in disease modeling, pharmacological screening, and regenerative medicine. (Copyright © 2026 The Author(s). Published by Elsevier B.V. All rights reserved.) |
| Competing Interests: | Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| Entry Date(s): | Date Created: 20260813 Date Completed: 20260910 Latest Revision: 20260910 |
| Update Code: | 20260911 |
| DOI: | 10.1016/j.scr.2026.104075 |
| PMID: | 42594645 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1876-7753 |
|---|---|
| DOI: | 10.1016/j.scr.2026.104075 |