Academic Journal
Mathematical and Computational Models of Biochemical Reactions and Cell Signaling-From Ordinary Differential Equations to Machine Learning.
| Τίτλος: | Mathematical and Computational Models of Biochemical Reactions and Cell Signaling-From Ordinary Differential Equations to Machine Learning. |
|---|---|
| Συγγραφείς: | Matyszczak G; Faculty of Chemistry, Warsaw University of Technology, Noakowski Street 3, 00-664 Warsaw, Poland. |
| Πηγή: | International journal of molecular sciences [Int J Mol Sci] 2026 Jul 30; Vol. 27 (15). Date of Electronic Publication: 2026 Jul 30. |
| Τύπος έκδοσης: | Journal Article; Review |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Basel, Switzerland : MDPI, [2000- |
| Ιατρικοί όροι (MeSH): | Signal Transduction* , Machine Learning* , Models, Biological* , Computer Simulation*, Systems Biology/methods ; Humans ; Animals ; Soft Computing |
| Περίληψη: | Cell signaling, and the biochemical reactions underlying it, are complex phenomena fundamental for control of cellular behavior in response to the incentives present in the cell's direct environment. It is crucial for coordination of cell activities such as growth, differentiation, metabolism, and death. The aim of this review is to present mathematical and computational models of biochemical reactions and cell signaling pathways in an educational and comprehensive way, outlining broad aspects of modeling such as differential equations, and artificial intelligence and machine learning approaches. This review also discusses potential applications of mathematical and computational models of cell signaling and biochemical reactions in fields such as systems biology, personalized medicine (i.e., cancer treatment, neurodegenerative disease treatment), and identification of drug targets. |
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| Contributed Indexing: | Keywords: biochemical reactions; cell signaling; enzyme kinetics; machine learning; mathematical modeling; ordinary differential equations; systems biology |
| Entry Date(s): | Date Created: 20260813 Date Completed: 20260813 Latest Revision: 20260815 |
| Update Code: | 20260815 |
| PubMed Central ID: | PMC13467184 |
| DOI: | 10.3390/ijms27156839 |
| PMID: | 42589495 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1422-0067 |
|---|---|
| DOI: | 10.3390/ijms27156839 |