Cost-effectiveness and patient-reported outcomes of combined versus isolated robotic rectal and pelvic organ prolapse repair: A multicentre prospective cohort study.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος:	Cost-effectiveness and patient-reported outcomes of combined versus isolated robotic rectal and pelvic organ prolapse repair: A multicentre prospective cohort study.
Συγγραφείς:	Wallace SL; Division of Urogynaecology and Pelvic Floor Disorders, Department of Obstetrics and Gynaecology, Cleveland Clinic Foundation, Cleveland, Ohio, USA., Ogilvie JW Jr; Division of Colorectal Surgery and Pelvic Floor Reconstruction, Corewell Health, Grand Rapids, Michigan, USA., Bordeianou L; Department of Surgery, Pelvic Floor Disorders Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Earley M; Department of Surgery, Pelvic Health Center, Stanford University, Stanford, California, USA., Platte R; Division of Colorectal Surgery and Pelvic Floor Reconstruction, Corewell Health, Grand Rapids, Michigan, USA., Weinstein MM; Department of Surgery, Pelvic Floor Disorders Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Sokol ER; Department of Gynecology, Stanford University, Stanford, California, USA., Enemchukwu EA; Department of Urology, Pelvic Health Center, Stanford University, Stanford, California, USA., Mishra K; Department of Gynecology, Stanford University, Stanford, California, USA., Gurland BH; Department of Surgery, Pelvic Health Center, Stanford University, Stanford, California, USA.
Πηγή:	Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland [Colorectal Dis] 2026 Aug; Vol. 28 (8), pp. e70570.
Τύπος έκδοσης:	Journal Article; Multicenter Study; Comparative Study
Γλώσσα:	English
Στοιχεία περιοδικού:	Publisher: Blackwell Science Ltd Country of Publication: England NLM ID: 100883611 Publication Model: Print Cited Medium: Internet ISSN: 1463-1318 (Electronic) Linking ISSN: 14628910 NLM ISO Abbreviation: Colorectal Dis Subsets: MEDLINE
Imprint Name(s):	Original Publication: Oxford, UK : Blackwell Science Ltd.
Ιατρικοί όροι (MeSH):	Pelvic Organ Prolapse/surgery , Pelvic Organ Prolapse/economics , Pelvic Organ Prolapse/complications , Rectal Prolapse/surgery , Rectal Prolapse/economics , Rectal Prolapse/complications , Robotic Surgical Procedures/economics , Robotic Surgical Procedures/methods , Patient Reported Outcome Measures* , Cost-Benefit Analysis*, Humans ; Female ; Prospective Studies ; Aged ; Middle Aged ; Cost-Effectiveness Analysis ; Quality of Life ; Quality-Adjusted Life Years ; Treatment Outcome ; Colorectal Surgical Procedures
Περίληψη:	Aim: Rectal prolapse (RP) and pelvic organ prolapse (POP) frequently coexist, yet are often evaluated and treated separately. This study aimed to compare patient-reported outcomes and cost-effectiveness of combined versus isolated robotic prolapse repair. Methods: We conducted a prospective multicentre cohort study across three tertiary pelvic floor centres. Women undergoing robotic rectal prolapse repair (rRP), robotic pelvic organ prolapse repair (rPOP) or combined robotic repair (rRP + rPOP) were included. Validated patient-reported outcome measures were collected at baseline and 12 months. Health utility was derived from EQ-5D-3L and used to calculate quality-adjusted life years (QALYs). A trial-based cost-effectiveness analysis was performed from the healthcare sector perspective. A theoretical cohort was modelled to examine staged versus combined repair in patients with multicompartment prolapse. Results: Forty-seven patients were included (rRP n = 14, rPOP n = 16, rRP + rPOP n = 17). All groups demonstrated significant improvement in pelvic floor symptoms and quality of life at 12 months. Improvements across bowel, bladder and prolapse-related domains were greatest in the combined repair group. Health utility gains were observed in all cohorts. In patients with multicompartment prolapse, combined robotic repair was cost-effective, whereas staged procedures were associated with higher cumulative costs without proportional gains in QALYs. Conclusions: Within robotic prolapse surgery, combined rectal and pelvic organ prolapse repair provides the most comprehensive symptom improvement and represents a cost-effective strategy when both compartments are symptomatic. These findings support systematic evaluation for multicompartment prolapse and multidisciplinary surgical planning. (© 2026 The Author(s). Colorectal Disease published by John Wiley & Sons Ltd on behalf of Association of Coloproctology of Great Britain and Ireland.)
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Contributed Indexing:	Keywords: cost‐effectiveness analysis; patient‐reported outcome measures; pelvic organ prolapse; rectal prolapse; robotic surgical procedures; ventral mesh rectopexy
Entry Date(s):	Date Created: 20260803 Date Completed: 20260803 Latest Revision: 20260813
Update Code:	20260814
PubMed Central ID:	PMC13429890
DOI:	10.1111/codi.70570
PMID:	42543563
Βάση Δεδομένων:	MEDLINE

Περιγραφή
ISSN:	1463-1318
DOI:	10.1111/codi.70570