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Theoretical modeling and numerical simulation of a light-field detector for x-ray differential phase contrast imaging.

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Τίτλος: Theoretical modeling and numerical simulation of a light-field detector for x-ray differential phase contrast imaging.
Συγγραφείς: Tan Y; Research Center for Advanced Detection Materials and Medical Imaging Devices, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China., Zhu J; Research Center for Advanced Detection Materials and Medical Imaging Devices, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China., Zhang X; Research Center for Advanced Detection Materials and Medical Imaging Devices, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China., Zheng H; Paul C Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.; State Key Laboratory of Biomedical Imaging Science and System, Shenzhen, Guangdong, China.; National Innovation Center for Advanced Medical Devices, Shenzhen, Guangdong, China., Liang D; Paul C Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.; State Key Laboratory of Biomedical Imaging Science and System, Shenzhen, Guangdong, China.; Research Center for Medical Artificial Intelligence, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China., Ge Y; Research Center for Advanced Detection Materials and Medical Imaging Devices, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.; Paul C Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.; State Key Laboratory of Biomedical Imaging Science and System, Shenzhen, Guangdong, China.; National Innovation Center for Advanced Medical Devices, Shenzhen, Guangdong, China.
Πηγή: Medical physics [Med Phys] 2026 Aug; Vol. 53 (8), pp. e70601.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: John Wiley and Sons, Inc Country of Publication: United States NLM ID: 0425746 Publication Model: Print Cited Medium: Internet ISSN: 2473-4209 (Electronic) Linking ISSN: 00942405 NLM ISO Abbreviation: Med Phys Subsets: MEDLINE
Imprint Name(s): Publication: 2017- : Hoboken, NJ : John Wiley and Sons, Inc.
Original Publication: Lancaster, Pa., Published for the American Assn. of Physicists in Medicine by the American Institute of Physics.
Ιατρικοί όροι (MeSH): Light* , Models, Theoretical* , Computer Simulation*, Oxides ; Titanium ; X-Rays ; Color ; Calcium Compounds
Περίληψη: Background: Most recently, a novel color-encoding light-field detector based on perovskite material has been demonstrated for x-ray differential phase contrast (DPC) imaging. However, it lacks performance evaluation and comparison between such a novel light-field detector and a widely used grating interferometer before applying it into medical imaging field.
Purpose: This study aims at evaluating and comparing the DPC imaging performance of the light-field detector and the grating interferometer.
Methods: In this work, a mathematical signal model was developed for the color-encoding perovskite light-field detector designed for x-ray DPC imaging. Specifically, the beam refraction angle was modeled based on the changes in the emitted color within the standard CIE1931 color space. Upon it, noise responses were derived. Numerical simulations were conducted to compare the sensitivity and signal variance of the perovskite light-field detector with those of a generic grating interferometer system. Additionally, impacts of the polychromatic x-ray beam and the Compton scattering were also investigated.
Results: It was found that the sensitivity of the perovskite light-field detector may surpass that of the grating interferometer if its color depth exceeds 30-bit (three 10-bit color channels). For perovskite light-field detectors, the signal noise increases as the detected refraction signal increases. In addition, polychromatic x-ray beam adds bias to the retrieved DPC signal, but has slight impact on the signal noise. Compton scattered x-ray photons could dramatically change the retrieved DPC signal.
Conclusion: This study demonstrates that the novel perovskite light-field detector may not be suitable for medical grade DPC imaging due to the inevitable Compton scatters. However, it might be a promising alternative to the grating interferometer in developing state-of-the-art scientific DPC imaging instruments for small sample ( INLINEMATH ), in which the impact of Compton scatters could be ignored.
(© 2026 American Association of Physicists in Medicine.)
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Grant Information: JCYJ20240813154930040 Shenzhen Science and Technology Program; JSGGKQTD20210831174329010 Shenzhen Science and Technology Program; KJZD20240903103201003 Shenzhen Science and Technology Program; 2024YFF0507800 National Key Research and Development Program of China; 2024YFF0507804 National Key Research and Development Program of China; 62422123 National Natural Science Foundation of China; 12505357 National Natural Science Foundation of China; U23A20284 National Natural Science Foundation of China
Contributed Indexing: Keywords: grating interferometer; perovskite light‐field detector; x‐ray differential phase contrast imaging
Substance Nomenclature: 0 (Oxides)
12194-71-7 (perovskite)
D1JT611TNE (Titanium)
0 (Calcium Compounds)
Entry Date(s): Date Created: 20260729 Date Completed: 20260729 Latest Revision: 20260801
Update Code: 20260801
PubMed Central ID: PMC13420989
DOI: 10.1002/mp.70601
PMID: 42527366
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:2473-4209
DOI:10.1002/mp.70601