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Recent advancements in phytotherapeutics for controlling babesiosis and theileriosis.

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Τίτλος: Recent advancements in phytotherapeutics for controlling babesiosis and theileriosis.
Συγγραφείς: Prajapati A; Biotechnology Research Innovation Council-National Institute of Animal Biotechnology (BRIC-NIAB), Gachibowli, Hyderabad, Telangana, 500032, India.; Regional Centre for Biotechnology (RCB), Faridabad, India., Rajput R; Biotechnology Research Innovation Council-National Institute of Animal Biotechnology (BRIC-NIAB), Gachibowli, Hyderabad, Telangana, 500032, India.; Regional Centre for Biotechnology (RCB), Faridabad, India., Srivastava A; Biotechnology Research Innovation Council-National Institute of Animal Biotechnology (BRIC-NIAB), Gachibowli, Hyderabad, Telangana, 500032, India. anand@niab.org.in.; Regional Centre for Biotechnology (RCB), Faridabad, India. anand@niab.org.in.
Πηγή: Tropical animal health and production [Trop Anim Health Prod] 2026 Jul 28; Vol. 58 (7). Date of Electronic Publication: 2026 Jul 28.
Τύπος έκδοσης: Journal Article; Review
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Springer Country of Publication: United States NLM ID: 1277355 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7438 (Electronic) Linking ISSN: 00494747 NLM ISO Abbreviation: Trop Anim Health Prod Subsets: MEDLINE
Imprint Name(s): Publication: 2005- : Heidelberg : Springer
Original Publication: Edinburgh, Livingstone.
Ιατρικοί όροι (MeSH): Babesiosis*/prevention & control , Babesiosis*/drug therapy , Babesiosis*/parasitology , Theileriasis*/drug therapy , Theileriasis*/prevention & control , Theileriasis*/parasitology , Plant Extracts*/therapeutic use , Plant Extracts*/pharmacology , Phytotherapy*/veterinary , Antiprotozoal Agents*/therapeutic use, Babesia/drug effects ; Theileria/drug effects ; Antiparasitic Agents/therapeutic use ; Animals
Περίληψη: Babesiosis/theileriosis is a tick-borne disease caused by protozoan parasites of the genus Babesia and Theileria. Tick species of genera, such as Ixodes, Rhipicephalus, Haemaphysalis and Hyalomma, transmit these parasites. These diseases threaten livestock productivity and health, particularly in tropical and subtropical areas. These diseases have a significant economic impact due to reduced milk and meat production, reproductive losses, higher veterinary expenses, and, in extreme cases, animal mortality. Even after decades of research, piroplasmosis is still difficult to control and manage. The most common drugs to treat this disease include buparvaquone, diminazene aceturate, and imidocarb dipropionate. These drugs are known for toxicity, and recent reports of the emergence of resistance to these drugs are worrisome. Hence, the development of alternative sustainable control methods is necessary. This review examines the current status of research on plant-based natural extracts/compounds, with particular emphasis on combination therapies integrating natural products with synthetic antiparasitic agents.
(© 2026. The Author(s), under exclusive licence to Springer Nature B.V.)
Competing Interests: Declarations. Conflict of interest: The authors declare they have no relevant financial or non-financial interests to disclose. There is no conflict of interest with any financial organization regarding the material discussed in the manuscript.
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Grant Information: BT/PR42271/TRM/120/511/2021 Department of Biotechnology, Ministry of Science and Technology, India; 3/1/3/JRF-2020/HRD(LS)/134663/49 ICMR; 211610035458 University Grants Commission
Contributed Indexing: Keywords: Babesiosis; Control strategies; Drugs; Piroplasmosis; Plant extracts; Theileriosis
Substance Nomenclature: 0 (Plant Extracts)
0 (Antiparasitic Agents)
0 (Antiprotozoal Agents)
Entry Date(s): Date Created: 20260728 Date Completed: 20260729 Latest Revision: 20260729
Update Code: 20260730
DOI: 10.1007/s11250-026-05260-x
PMID: 42521938
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1573-7438
DOI:10.1007/s11250-026-05260-x