Academic Journal
Effect of Ultrasound-Guided Sciatic and Saphenous Nerve Blocks on Analgesia During General Anaesthesia for Ankle Fracture Surgery: A Randomised Controlled Trial.
| Τίτλος: | Effect of Ultrasound-Guided Sciatic and Saphenous Nerve Blocks on Analgesia During General Anaesthesia for Ankle Fracture Surgery: A Randomised Controlled Trial. |
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| Συγγραφείς: | John HJ; Department of Anaesthesiology and Pain Medicine, College of Medicine, Hallym University, Hallym University Sacred Heart Hospital, Anyang 14068, Republic of Korea., Choi JB; Department of Anaesthesiology and Pain Medicine, College of Medicine, Ajou University School of Medicine, Suwon 16499, Republic of Korea., Jang MS; Department of Anaesthesiology and Pain Medicine, College of Medicine, Hallym University, Hallym University Sacred Heart Hospital, Anyang 14068, Republic of Korea., Lee CY; Department of Anaesthesiology and Pain Medicine, College of Medicine, Hallym University, Hallym University Sacred Heart Hospital, Anyang 14068, Republic of Korea., Jeong S; Department of Anaesthesiology and Pain Medicine, College of Medicine, Hallym University, Hallym University Sacred Heart Hospital, Anyang 14068, Republic of Korea., Kim JY; Department of Anaesthesiology and Pain Medicine, College of Medicine, Ajou University School of Medicine, Suwon 16499, Republic of Korea., Zein M; Interventional Spine & Pain Medicine, Department of Neurosurgery, Division of Spine Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Park JY; Department of Orthopaedic Surgery, College of Medicine, Hallym University, Hallym University Sacred Heart Hospital, Anyang 14068, Republic of Korea., Lee SK; Department of Anaesthesiology and Pain Medicine, College of Medicine, Hallym University, Hallym University Sacred Heart Hospital, Anyang 14068, Republic of Korea., Choi YH; Department of Anaesthesiology and Pain Medicine, College of Medicine, Hallym University, Hallym University Sacred Heart Hospital, Anyang 14068, Republic of Korea. |
| Πηγή: | Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2026 Jul 21; Vol. 62 (7). Date of Electronic Publication: 2026 Jul 21. |
| Τύπος έκδοσης: | Journal Article; Randomized Controlled Trial |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 9425208 Publication Model: Electronic Cited Medium: Internet ISSN: 1648-9144 (Electronic) Linking ISSN: 1010660X NLM ISO Abbreviation: Medicina (Kaunas) Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2018- : Basel, Switzerland : MDPI Original Publication: Kaunas : Lietuvos gydytojų sąjunga |
| Ιατρικοί όροι (MeSH): | Ankle Fractures*/surgery , Nerve Block*/methods , Nerve Block*/standards , Anesthesia, General*/methods , Anesthesia, General*/standards , Analgesia*/methods , Analgesia*/standards, Postoperative Pain/drug therapy ; Postoperative Pain/prevention & control ; Ultrasonography, Interventional/methods ; Sciatic Nerve/drug effects ; Remifentanil/therapeutic use ; Pain Measurement/methods ; Humans ; Female ; Male ; Middle Aged ; Adult ; Aged |
| Περίληψη: | Background and Objectives: Ultrasound-guided sciatic and saphenous nerve blocks are widely used as analgesic alternatives for multimodal analgesia. However, how to objectively quantify the opioid- and anaesthetic-sparing effects of an additional peripheral nerve block in patients undergoing ankle fracture surgery under general anaesthesia remains unclear. This study aimed to evaluate their efficacy in managing postoperative pain and opioid-sparing effects following ankle fracture surgery. Materials and Methods: Patients scheduled for ankle fracture surgery were randomly assigned to the nerve block (n = 30) or control group (n = 30). The primary outcome was the postoperative numeric rating scale (NRS) score. The secondary outcomes included the total doses of remifentanil and propofol, Quality of Recovery-40 Korean (QoR-40K) scores, and self-reported patient satisfaction. Results: The NRS score immediately after surgery was significantly lower in the nerve block group compared with that in the control group (2.6 ± 2.5 vs. 6.2 ± 2.6; p < 0.001). The total remifentanil dose required during surgery was also significantly lower in the nerve block group than in the control group (1148.1 ± 391.8 vs. 1487.4 ± 798.8; p = 0.041). However, the patient satisfaction scale (3 [IQR, 2-4] vs. 3 [IQR, 2-4]; p = 0.206) and QoR-40K score 24 h after surgery (169 [IQR, 155-184] vs. 175 [IQR, 154-165]; p = 0.324) did not differ significantly between the two groups. Conclusions: Ultrasound-guided sciatic and saphenous nerve blocks significantly reduced immediate postoperative pain and intraoperative remifentanil consumption under qNOX (quantitative nociception index)-guided general anaesthesia during ankle fracture surgery. |
| Contributed Indexing: | Keywords: anaesthesia; analgesics; nerve block; postoperative pain; regional analgesia; ultrasound guidance |
| Substance Nomenclature: | P10582JYYK (Remifentanil) |
| Entry Date(s): | Date Created: 20260728 Date Completed: 20260729 Latest Revision: 20260731 |
| Update Code: | 20260731 |
| PubMed Central ID: | PMC13414385 |
| DOI: | 10.3390/medicina62071410 |
| PMID: | 42512952 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1648-9144 |
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| DOI: | 10.3390/medicina62071410 |