Academic Journal
Ultra-Low-Field Brain MRI for Point-of-Care Applications: A Technology Review.
| Τίτλος: | Ultra-Low-Field Brain MRI for Point-of-Care Applications: A Technology Review. |
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| Συγγραφείς: | Wu EX; Laboratory of Biomedical Imaging and Signal Processing (E.X.W., Y.Z., Y.D., A.T.L.L.), The University of Hong Kong, Hong Kong SAR, China.; Department of Electrical and Computer Engineering (E.X.W., Y.Z., Y.D., A.T.L.L.), The University of Hong Kong, Hong Kong SAR, China., Zhao Y; Laboratory of Biomedical Imaging and Signal Processing (E.X.W., Y.Z., Y.D., A.T.L.L.), The University of Hong Kong, Hong Kong SAR, China.; Department of Electrical and Computer Engineering (E.X.W., Y.Z., Y.D., A.T.L.L.), The University of Hong Kong, Hong Kong SAR, China., Liu Y; Key Laboratory of CNS Regeneration (Ministry of Education), Guangdong-Hongkong-Macau CNS Regeneration Institute, Jinan University, Guangzhou, China (Y.L.)., Ding Y; Laboratory of Biomedical Imaging and Signal Processing (E.X.W., Y.Z., Y.D., A.T.L.L.), The University of Hong Kong, Hong Kong SAR, China.; Department of Electrical and Computer Engineering (E.X.W., Y.Z., Y.D., A.T.L.L.), The University of Hong Kong, Hong Kong SAR, China., Wald LL; A.A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown (L.L.W., J.E.I.)., Iglesias JE; A.A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown (L.L.W., J.E.I.).; Hawkes Institute, University College London, United Kingdom (J.E.I.)., Webb AG; C.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, the Netherlands (A.G.W.)., Hennig J; Department of Radiology, Medical Physics, Faculty of Medicine, University of Freiburg, Germany (J.H.)., Leung GKK; Department of Surgery, Li Ka Shing Faculty of Medicine (G.K.K.L.), The University of Hong Kong, Hong Kong SAR, China., Leong ATL; Laboratory of Biomedical Imaging and Signal Processing (E.X.W., Y.Z., Y.D., A.T.L.L.), The University of Hong Kong, Hong Kong SAR, China.; Department of Electrical and Computer Engineering (E.X.W., Y.Z., Y.D., A.T.L.L.), The University of Hong Kong, Hong Kong SAR, China. |
| Πηγή: | Stroke [Stroke] 2026 Sep; Vol. 57 (9), pp. 2577-2589. Date of Electronic Publication: 2026 Jul 21. |
| Τύπος έκδοσης: | Journal Article; Review |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0235266 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4628 (Electronic) Linking ISSN: 00392499 NLM ISO Abbreviation: Stroke Subsets: MEDLINE |
| Imprint Name(s): | Publication: 1998- : Baltimore, Md. : Lippincott Williams & Wilkins Original Publication: Dallas : American Heart Association |
| Ιατρικοί όροι (MeSH): | Magnetic Resonance Imaging*/methods , Magnetic Resonance Imaging*/instrumentation , Brain*/pathology , Brain*/diagnostic imaging , Neuroimaging*/methods , Neuroimaging*/instrumentation , Stroke*/diagnostic imaging , Point-of-Care Systems*, Humans ; Brain Neoplasms |
| Περίληψη: | Magnetic resonance imaging (MRI) is a cornerstone of neurological care, serving as the gold standard for diagnosing pathologies, such as brain tumors and, together with computed tomography, stroke. However, the high capital costs, specialized infrastructure requirements such as expensive and bulky radiofrequency-shielding cages, and the operational complexity of conventional high-field scanners (1.5T and 3T) largely confine MRI to centralized imaging facilities. This scenario often leads to reliance on brain computed tomography or ultrasound in point-of-care settings, despite MRI's superior soft-tissue contrast for diagnosis and prognosis. In the past decade, there has been renewed interest in compact and simplified ultra-low-field (under 0.1T) MRI scanners, fueled by advances in engineering and computing. Here, we review the recent developments in ultra-low-field brain MRI, which enable imaging in open environments and demonstrate initial clinical applicability in point-of-care settings. We also envision future developments along 3 focus areas (ie, hardware, imaging protocols, and data-driven image formation and analysis) to address the current limitations of image quality and contrast in ultra-low-field brain MRI systems. |
| Competing Interests: | Dr Wald is a founder of and holds stock holdings in Neuro42, Inc, which makes portable brain magnetic resonance imaging. Dr Wald also receives compensation from Neuro42, Inc, for consultant services; holds a patent US10,359,481, which is licensed to Neuro42, Inc; and reports grants from Siemens Medical Solutions USA, Inc. Drs Wald and Iglesias report grants from the National Institutes of Health. The other authors report no conflicts. |
| Contributed Indexing: | Keywords: brain neoplasms; delivery of healthcare; intensive care units; ischemic stroke; magnetic resonance imaging; neuroimaging; point-of-care systems |
| Entry Date(s): | Date Created: 20260721 Date Completed: 20260824 Latest Revision: 20260824 |
| Update Code: | 20260825 |
| DOI: | 10.1161/STROKEAHA.126.052978 |
| PMID: | 42478365 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1524-4628 |
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| DOI: | 10.1161/STROKEAHA.126.052978 |