Academic Journal
Nutritional and toxicological trade-offs in selenium enrichment: a bioaccessibility-based comparison of biofortified and naturally enriched foods.
| Title: | Nutritional and toxicological trade-offs in selenium enrichment: a bioaccessibility-based comparison of biofortified and naturally enriched foods. |
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| Authors: | Belarbi H; Center of Excellence in Soil and Fertilizer Research in Africa, College of Agriculture and Environmental Science, Mohammed VI Polytechnic University, 43150 Benguerir, Morocco; Laboratory of Analytical Chemistry and Applied Ecochemistry, Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Frieda Saeystraat 1, 9052 Zwijnaarde, Belgium. Electronic address: hind.belarbi@um6p.ma., Algoet V; Laboratory of Analytical Chemistry and Applied Ecochemistry, Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Frieda Saeystraat 1, 9052 Zwijnaarde, Belgium., Neri J; Laboratory of Analytical Chemistry and Applied Ecochemistry, Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Frieda Saeystraat 1, 9052 Zwijnaarde, Belgium., Kebede F; Center of Excellence in Soil and Fertilizer Research in Africa, College of Agriculture and Environmental Science, Mohammed VI Polytechnic University, 43150 Benguerir, Morocco., Dos Reis AR; School of Sciences and Engineering, São Paulo State University (UNESP), Tupã 17602-496, São Paulo, Brazil., Sun GX; State Key Laboratory of Regional and Urban Ecology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, 100085 Beijing, China., Van de Wiele T; Faculty of Engineering & Natural Sciences, Sabanci University, 34956 Istanbul, Turkey., Cakmak I; Center for Microbial Ecology and Technology, Faculty of Bioscience Engineering (CMET), Ghent University, Frieda Saeystraat 1, 9052 Zwijnaarde, Belgium., Du Laing G; Laboratory of Analytical Chemistry and Applied Ecochemistry, Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Frieda Saeystraat 1, 9052 Zwijnaarde, Belgium. |
| Source: | Food chemistry [Food Chem] 2026 Oct 01; Vol. 525 (Pt 2), pp. 150400. Date of Electronic Publication: 2026 Jul 16. |
| Publication Type: | Journal Article; Comparative Study |
| Language: | English |
| Journal Info: | Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE |
| Imprint Name(s): | Publication: Barking : Elsevier Applied Science Publishers Original Publication: Barking, Eng., Applied Science Publishers. |
| MeSH Terms: | Selenium*/analysis , Selenium*/metabolism , Selenium*/toxicity , Food, Fortified*/analysis , Oryza*/chemistry , Oryza*/metabolism, Tea/chemistry ; Arsenic/analysis ; Arsenic/metabolism ; Biofortification ; Nutritive Value ; Humans ; Brazil ; Biological Availability ; Animals |
| Abstract: | Geological variation in soil selenium (Se) content shapes both the nutritional value and toxicological risk of food crops. This study compared Se-biofortified rice from Brazil with naturally Se-enriched rice, cereal-based noodles, teas, meat snacks, and supplements from seleniferous regions of China. Total Se and As concentrations, dietary intake, and bioaccessibility were further assessed using in vitro digestion. Brazilian biofortified rice contained 175-9037 μg/kg Se with negligible As (≤1 μg/kg), while geogenic rice showed 76-995 μg/kg Se and 48-321 μg/kg As. Cooking reduced As by up to 71%. Selenium intakes remained within safe limits across all products, though As exposure from geogenic rice exceeded EFSA thresholds (HQ > 3). Selenium bioaccessibility averaged 24% in cereals, 22% in supplements and up to 69% in teas, decreasing significantly with ultrafiltration. These results show the need to tailor Se enrichment strategies to local geochemical contexts to balance nutritional benefits with contaminant risks. (Copyright © 2026 Elsevier Ltd. All rights reserved.) |
| Competing Interests: | Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| Contributed Indexing: | Keywords: Arsenic exposure; Bioaccessibility; Biofortification; Dietary intake; Geogenic enrichment; Selenium |
| Substance Nomenclature: | H6241UJ22B (Selenium) 0 (Tea) N712M78A8G (Arsenic) |
| Entry Date(s): | Date Created: 20260718 Date Completed: 20260906 Latest Revision: 20260906 |
| Update Code: | 20260906 |
| DOI: | 10.1016/j.foodchem.2026.150400 |
| PMID: | 42470887 |
| Database: | MEDLINE |
| ISSN: | 1873-7072 |
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| DOI: | 10.1016/j.foodchem.2026.150400 |