Academic Journal
Fast and compact scatterometer for ex vivo qualification of low-scattering biological samples.
| Τίτλος: | Fast and compact scatterometer for ex vivo qualification of low-scattering biological samples. |
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| Συγγραφείς: | Sarrade A; Aix Marseille Univ, CNRS, Centrale Med, Institut Fresnel, Marseille, France.; Ramsay Générale de Santé, Clinique Monticelli-Velodrome, Marseille, France., El Allam J; Aix Marseille Univ, CNRS, Centrale Med, Institut Fresnel, Marseille, France., Espinas V; Aix Marseille Univ, CNRS, Centrale Med, Institut Fresnel, Marseille, France.; Centre Européen de Recherche en Imagerie Médicale (CERIMED), Aix-Marseille University, CNRS, Marseille, France., Hoffart L; Ramsay Générale de Santé, Clinique Monticelli-Velodrome, Marseille, France., Picard C; Tissue Bank, French Blood Establishment, Marseille, France.; ADES, French Blood Establishment/Aix-Marseille University/CNRS, Marseille, France., David T; Aix Marseille Univ, CNRS, Centrale Med, Institut Fresnel, Marseille, France., Georges G; Aix Marseille Univ, CNRS, Centrale Med, Institut Fresnel, Marseille, France., Deumié C; Aix Marseille Univ, CNRS, Centrale Med, Institut Fresnel, Marseille, France.; Centre Européen de Recherche en Imagerie Médicale (CERIMED), Aix-Marseille University, CNRS, Marseille, France., Siozade Lamoine L; Aix Marseille Univ, CNRS, Centrale Med, Institut Fresnel, Marseille, France.; Centre Européen de Recherche en Imagerie Médicale (CERIMED), Aix-Marseille University, CNRS, Marseille, France., Fade J; Aix Marseille Univ, CNRS, Centrale Med, Institut Fresnel, Marseille, France.; Centre Européen de Recherche en Imagerie Médicale (CERIMED), Aix-Marseille University, CNRS, Marseille, France. |
| Πηγή: | The Review of scientific instruments [Rev Sci Instrum] 2026 Jul 01; Vol. 97 (7). |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: American Institute Of Physics Country of Publication: United States NLM ID: 0405571 Publication Model: Print Cited Medium: Internet ISSN: 1089-7623 (Electronic) Linking ISSN: 00346748 NLM ISO Abbreviation: Rev Sci Instrum Subsets: MEDLINE |
| Imprint Name(s): | Publication: 1933- : Woodbury, N.Y. : American Institute Of Physics Original Publication: 1930-1932 : Menasha, WI : Optical Society of America |
| Ιατρικοί όροι (MeSH): | Scattering, Radiation* , Cornea*, Humans ; Calibration ; Time Factors ; Equipment Design ; Light |
| Περίληψη: | We present the design, calibration, qualification, and application of a fast and compact scatterometer designed for the characterization of ex vivo human corneas. As an alternative to standard qualification processes and in order to meet the current need for improved reliability of graft qualification, this instrument provides a non-invasive, label-free, and contact-free quantitative means of characterizing corneal grafts, based on back-scattered light diffusometry. The instrument is shown to be capable of detecting BRDF (bidirectional reflectance distribution function) variations of 1.4 × 10-4 sr-1 with a detectivity threshold of 2.0 × 10-3 sr-1, with an overall dynamics >27 dB for the total integrated scattering parameter used for graft quality assessment. We also demonstrate the feasibility of integrating this new technique into tissue bank qualification processes through controlled test experiments reported here. (© 2026 Author(s). Published under an exclusive license by AIP Publishing.) |
| Entry Date(s): | Date Created: 20260713 Date Completed: 20260713 Latest Revision: 20260713 |
| Update Code: | 20260713 |
| DOI: | 10.1063/5.0327390 |
| PMID: | 42439722 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1089-7623 |
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| DOI: | 10.1063/5.0327390 |