Academic Journal
Correlation of Transcutaneous pCO2 and Capillary pCO2 in Newborn Patients Depending on Gestational Age: A Secondary Data Analysis.
| Τίτλος: | Correlation of Transcutaneous pCO |
|---|---|
| Συγγραφείς: | Olivier L; Division of Neonatology, Department of Pediatric and Adolescent Medicine, Uniklinik RWTH Aachen, Aachen, Germany., Lauterbach Oprea C; Chair of Embedded Software (Computer Science 11), RWTH Aachen University, Aachen, Germany., Stollenwerk A; Chair of Embedded Software (Computer Science 11), RWTH Aachen University, Aachen, Germany., Pfannschmidt V; Chair of Embedded Software (Computer Science 11), RWTH Aachen University, Aachen, Germany., Orlikowsky T; Division of Neonatology, Department of Pediatric and Adolescent Medicine, Uniklinik RWTH Aachen, Aachen, Germany., Schoberer M; Division of Neonatology, Department of Pediatric and Adolescent Medicine, Uniklinik RWTH Aachen, Aachen, Germany. |
| Πηγή: | Pediatric pulmonology [Pediatr Pulmonol] 2026 Jul; Vol. 61 (7), pp. e71733. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8510590 Publication Model: Print Cited Medium: Internet ISSN: 1099-0496 (Electronic) Linking ISSN: 10990496 NLM ISO Abbreviation: Pediatr Pulmonol Subsets: MEDLINE |
| Imprint Name(s): | Publication: <2005-> : Hoboken, NJ : Wiley-Liss Original Publication: [Philadelphia, PA] : W.B. Saunders, [c1985- |
| Ιατρικοί όροι (MeSH): | Carbon Dioxide*/blood , Blood Gas Monitoring, Transcutaneous*/methods , Gestational Age* , Capillaries*, Humans ; Infant, Newborn ; Female ; Male ; Intensive Care Units, Neonatal ; Infant, Premature ; Partial Pressure ; Infant, Extremely Premature ; Cohort Studies |
| Περίληψη: | Introduction: Transcutaneous monitoring of CO Methods: Single-center secondary data cohort study at a Tertiary Care NICU. 116 neonates undergoing tcpCO Results: 926 simultaneous measurements were included. The evaluation of the linear mixed-effects model revealed a significant effect of gestational age on ΔpCO Conclusions: The gestational age has a significant directed effect on the accuracy of transcutaneous CO (© 2026 The Author(s). Pediatric Pulmonology published by Wiley Periodicals LLC.) |
| References: | Am J Perinatol. 1994 May;11(3):237-41. (PMID: 8048993) Cytometry B Clin Cytom. 2003 Jul;54(1):46-53. (PMID: 12827667) Semin Fetal Neonatal Med. 2009 Feb;14(1):21-7. (PMID: 18974027) Biotelem Patient Monit. 1982;9(1):28-35. (PMID: 6809070) J Physiol. 2011 Jun 15;589(Pt 12):3039-48. (PMID: 21521758) BMC Pediatr. 2005 Aug 10;5:30. (PMID: 16092957) Skin Pharmacol Physiol. 2004 Mar-Apr;17(2):57-66. (PMID: 14976382) Pediatrics. 2014 Jan;133(1):55-62. (PMID: 24379238) Paediatr Respir Rev. 2013 Mar;14(1):29-36; quiz 36-7. (PMID: 23347658) J Perinatol. 2005 Jan;25(1):26-9. (PMID: 15496874) JAMA Pediatr. 2015 Sep;169(9):855-62. (PMID: 26214387) Crit Care Med. 1997 Nov;25(11):1904-8. (PMID: 9366777) Crit Care Res Pract. 2016;2016:8041967. (PMID: 27375901) Am J Perinatol. 2017 Apr;34(5):480-485. (PMID: 27673754) J Pediatr. 2024 Jun;269:114002. (PMID: 38447757) Iran J Pediatr. 2015 Feb;25(1):e184. (PMID: 26199686) Pediatrics. 2007 Feb;119(2):299-305. (PMID: 17272619) Pan Afr Med J. 2021 May 25;39:66. (PMID: 34422189) J Clin Med. 2023 Sep 04;12(17):. (PMID: 37685823) Pediatrics. 2006 Oct;118(4):1654-9. (PMID: 17015558) Med Biol Eng Comput. 2020 Feb;58(2):239-247. (PMID: 31741291) Biochem Med (Zagreb). 2015 Oct 15;25(3):335-58. (PMID: 26524965) Pediatrics. 1988 May;81(5):684-7. (PMID: 3128769) Thorax. 2019 Feb;74(2):157-163. (PMID: 30209079) Pediatr Res. 1980 Dec;14(12):1374-8. (PMID: 7208156) Arch Dis Child. 1984 Oct;59(10):957-61. (PMID: 6497433) Acta Paediatr. 2011 May;100(5):676-9. (PMID: 21244487) JAMA. 2013 Nov 27;310(20):2191-4. (PMID: 24141714) J Clin Epidemiol. 2008 Apr;61(4):344-9. (PMID: 18313558) JAMA Netw Open. 2020 Jun 1;3(6):e205239. (PMID: 32556257) Respir Care. 2020 May;65(5):693-704. (PMID: 32209710) Pediatr Res. 2024 Aug;96(3):595-603. (PMID: 36593283) J Invest Dermatol. 1998 Aug;111(2):320-6. (PMID: 9699737) Anesth Analg. 2007 Dec;105(6 Suppl):S48-S52. (PMID: 18048898) Compr Physiol. 2012 Jul;2(3):2203-54. (PMID: 23723036) Neonatology. 2022;119(2):230-237. (PMID: 35124680) Am J Perinatol. 2014 May;31(5):435-40. (PMID: 23918520) Semin Neonatol. 2000 Nov;5(4):273-80. (PMID: 11032710) Klin Padiatr. 2016 Sep;228(5):245-50. (PMID: 27617760) Respir Care. 2016 Jan;61(1):90-7. (PMID: 26508771) Crit Care Med. 2005 Oct;33(10):2203-6. (PMID: 16215371) Arch Dis Child. 1990 Apr;65(4 Spec No):345-6. (PMID: 2110802) Acta Paediatr. 2020 Apr;109(4):679-687. (PMID: 31505053) |
| Grant Information: | 031L0303 BMFTR |
| Contributed Indexing: | Keywords: carbon dioxide; neonatal intensive care unit; neonate; premature infants; transcutaneous blood gas monitoring; transcutaneous capnometry |
| Substance Nomenclature: | 142M471B3J (Carbon Dioxide) |
| Entry Date(s): | Date Created: 20260713 Date Completed: 20260713 Latest Revision: 20260813 |
| Update Code: | 20260814 |
| PubMed Central ID: | PMC13358317 |
| DOI: | 10.1002/ppul.71733 |
| PMID: | 42438310 |
| Βάση Δεδομένων: | MEDLINE |
| FullText | Links: – Type: other Url: https://resolver.ebsco.com:443/public/rma-ftfapi/ejs/direct?AccessToken=44DCAC666A6747269741&Show=Object Text: Availability: 0 |
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| Header | DbId: cmedm DbLabel: MEDLINE An: 42438310 AccessLevel: 3 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Correlation of Transcutaneous pCO<subscript>2</subscript> and Capillary pCO<subscript>2</subscript> in Newborn Patients Depending on Gestational Age: A Secondary Data Analysis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Olivier+L%22">Olivier L</searchLink>; Division of Neonatology, Department of Pediatric and Adolescent Medicine, Uniklinik RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Lauterbach+Oprea+C%22">Lauterbach Oprea C</searchLink>; Chair of Embedded Software (Computer Science 11), RWTH Aachen University, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Stollenwerk+A%22">Stollenwerk A</searchLink>; Chair of Embedded Software (Computer Science 11), RWTH Aachen University, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Pfannschmidt+V%22">Pfannschmidt V</searchLink>; Chair of Embedded Software (Computer Science 11), RWTH Aachen University, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Orlikowsky+T%22">Orlikowsky T</searchLink>; Division of Neonatology, Department of Pediatric and Adolescent Medicine, Uniklinik RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Schoberer+M%22">Schoberer M</searchLink>; Division of Neonatology, Department of Pediatric and Adolescent Medicine, Uniklinik RWTH Aachen, Aachen, Germany. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228510590%22">Pediatric pulmonology</searchLink> [Pediatr Pulmonol] 2026 Jul; Vol. 61 (7), pp. e71733. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: Language Label: Language Group: Lang Data: English – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Liss%22">Wiley-Liss </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8510590 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1099-0496 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210990496%22">10990496 </searchLink><i>NLM ISO Abbreviation: </i>Pediatr Pulmonol <i>Subsets: </i>MEDLINE – Name: PublisherInfo Label: Imprint Name(s) Group: PubInfo Data: <i>Publication</i>: <2005-> : Hoboken, NJ : Wiley-Liss<br /><i>Original Publication</i>: [Philadelphia, PA] : W.B. Saunders, [c1985- – Name: SubjectMESH Label: MeSH Terms Group: Su Data: <searchLink fieldCode="MM" term="%22Carbon+Dioxide%22">Carbon Dioxide*</searchLink>/<searchLink fieldCode="MM" term="%22Carbon+Dioxide+blood%22">blood</searchLink> <br /><searchLink fieldCode="MM" term="%22Blood+Gas+Monitoring%2C+Transcutaneous%22">Blood Gas Monitoring, Transcutaneous*</searchLink>/<searchLink fieldCode="MM" term="%22Blood+Gas+Monitoring%2C+Transcutaneous+methods%22">methods</searchLink> <br /><searchLink fieldCode="MM" term="%22Gestational+Age%22">Gestational Age*</searchLink> <br /><searchLink fieldCode="MM" term="%22Capillaries%22">Capillaries*</searchLink><br /><searchLink fieldCode="MH" term="%22Humans%22">Humans</searchLink> ; <searchLink fieldCode="MH" term="%22Infant%2C+Newborn%22">Infant, Newborn</searchLink> ; <searchLink fieldCode="MH" term="%22Female%22">Female</searchLink> ; <searchLink fieldCode="MH" term="%22Male%22">Male</searchLink> ; <searchLink fieldCode="MH" term="%22Intensive+Care+Units%2C+Neonatal%22">Intensive Care Units, Neonatal</searchLink> ; <searchLink fieldCode="MH" term="%22Infant%2C+Premature%22">Infant, Premature</searchLink> ; <searchLink fieldCode="MH" term="%22Partial+Pressure%22">Partial Pressure</searchLink> ; <searchLink fieldCode="MH" term="%22Infant%2C+Extremely+Premature%22">Infant, Extremely Premature</searchLink> ; <searchLink fieldCode="MH" term="%22Cohort+Studies%22">Cohort Studies</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Introduction: Transcutaneous monitoring of CO<subscript>2</subscript> partial pressure (tcpCO<subscript>2</subscript>) provides continuous information about the CO<subscript>2</subscript> partial pressure in the blood (pCO<subscript>2</subscript>). However, the deviation of tcpCO<subscript>2</subscript> from pCO<subscript>2</subscript> is variable. Our aim was to assess whether this deviation depends on gestational age in the first postnatal week.<br />Methods: Single-center secondary data cohort study at a Tertiary Care NICU. 116 neonates undergoing tcpCO<subscript>2</subscript> monitoring were included. A linear mixed-effects model was used to analyze the difference between tcpCO<subscript>2</subscript> and capillary pCO<subscript>2</subscript> (ΔpCO<subscript>2</subscript>) in the first postnatal week.<br />Results: 926 simultaneous measurements were included. The evaluation of the linear mixed-effects model revealed a significant effect of gestational age on ΔpCO<subscript>2</subscript>. Median [interquartile 1; interquartile 3] ΔpCO<subscript>2</subscript> was significantly higher for extremely preterm infants (&lt; 28 weeks) with 7.6 [2.4; 13.9] mmHg compared to 3.1 [-1.0; 6.4] mmHg for very preterm (28-31 + 6 weeks), 0.6 [-4.6; 4.7] mmHg for late preterm (32-36 + 6 weeks) and -0.5 [-4.8; 4.7] mmHg for term infants (≥ 37 weeks). There were no significant differences in ΔpCO<subscript>2</subscript> between patients born at 23 to 25 compared to 26 and 27 completed weeks of gestation. In multivariable analysis, gestational age, early-onset bacterial infection and capillary pCO<subscript>2</subscript> were independently associated with ΔpCO<subscript>2</subscript>, whereas birth weight was not.<br />Conclusions: The gestational age has a significant directed effect on the accuracy of transcutaneous CO<subscript>2</subscript> monitoring in preterm neonates and can-together with other known influence factors-be used to improve the non-invasive pCO<subscript>2</subscript> estimation.<br /> (© 2026 The Author(s). Pediatric Pulmonology published by Wiley Periodicals LLC.) – Name: Ref Label: References Group: RefInfo Data: Am J Perinatol. 1994 May;11(3):237-41. (PMID: <searchLink fieldCode="PM" term="%228048993%22">8048993)</searchLink><br />Cytometry B Clin Cytom. 2003 Jul;54(1):46-53. (PMID: <searchLink fieldCode="PM" term="%2212827667%22">12827667)</searchLink><br />Semin Fetal Neonatal Med. 2009 Feb;14(1):21-7. (PMID: <searchLink fieldCode="PM" term="%2218974027%22">18974027)</searchLink><br />Biotelem Patient Monit. 1982;9(1):28-35. (PMID: <searchLink fieldCode="PM" term="%226809070%22">6809070)</searchLink><br />J Physiol. 2011 Jun 15;589(Pt 12):3039-48. (PMID: <searchLink fieldCode="PM" term="%2221521758%22">21521758)</searchLink><br />BMC Pediatr. 2005 Aug 10;5:30. (PMID: <searchLink fieldCode="PM" term="%2216092957%22">16092957)</searchLink><br />Skin Pharmacol Physiol. 2004 Mar-Apr;17(2):57-66. (PMID: <searchLink fieldCode="PM" term="%2214976382%22">14976382)</searchLink><br />Pediatrics. 2014 Jan;133(1):55-62. (PMID: <searchLink fieldCode="PM" term="%2224379238%22">24379238)</searchLink><br />Paediatr Respir Rev. 2013 Mar;14(1):29-36; quiz 36-7. (PMID: <searchLink fieldCode="PM" term="%2223347658%22">23347658)</searchLink><br />J Perinatol. 2005 Jan;25(1):26-9. (PMID: <searchLink fieldCode="PM" term="%2215496874%22">15496874)</searchLink><br />JAMA Pediatr. 2015 Sep;169(9):855-62. (PMID: <searchLink fieldCode="PM" term="%2226214387%22">26214387)</searchLink><br />Crit Care Med. 1997 Nov;25(11):1904-8. (PMID: <searchLink fieldCode="PM" term="%229366777%22">9366777)</searchLink><br />Crit Care Res Pract. 2016;2016:8041967. (PMID: <searchLink fieldCode="PM" term="%2227375901%22">27375901)</searchLink><br />Am J Perinatol. 2017 Apr;34(5):480-485. (PMID: <searchLink fieldCode="PM" term="%2227673754%22">27673754)</searchLink><br />J Pediatr. 2024 Jun;269:114002. (PMID: <searchLink fieldCode="PM" term="%2238447757%22">38447757)</searchLink><br />Iran J Pediatr. 2015 Feb;25(1):e184. (PMID: <searchLink fieldCode="PM" term="%2226199686%22">26199686)</searchLink><br />Pediatrics. 2007 Feb;119(2):299-305. (PMID: <searchLink fieldCode="PM" term="%2217272619%22">17272619)</searchLink><br />Pan Afr Med J. 2021 May 25;39:66. (PMID: <searchLink fieldCode="PM" term="%2234422189%22">34422189)</searchLink><br />J Clin Med. 2023 Sep 04;12(17):. (PMID: <searchLink fieldCode="PM" term="%2237685823%22">37685823)</searchLink><br />Pediatrics. 2006 Oct;118(4):1654-9. (PMID: <searchLink fieldCode="PM" term="%2217015558%22">17015558)</searchLink><br />Med Biol Eng Comput. 2020 Feb;58(2):239-247. (PMID: <searchLink fieldCode="PM" term="%2231741291%22">31741291)</searchLink><br />Biochem Med (Zagreb). 2015 Oct 15;25(3):335-58. (PMID: <searchLink fieldCode="PM" term="%2226524965%22">26524965)</searchLink><br />Pediatrics. 1988 May;81(5):684-7. (PMID: <searchLink fieldCode="PM" term="%223128769%22">3128769)</searchLink><br />Thorax. 2019 Feb;74(2):157-163. (PMID: <searchLink fieldCode="PM" term="%2230209079%22">30209079)</searchLink><br />Pediatr Res. 1980 Dec;14(12):1374-8. (PMID: <searchLink fieldCode="PM" term="%227208156%22">7208156)</searchLink><br />Arch Dis Child. 1984 Oct;59(10):957-61. (PMID: <searchLink fieldCode="PM" term="%226497433%22">6497433)</searchLink><br />Acta Paediatr. 2011 May;100(5):676-9. (PMID: <searchLink fieldCode="PM" term="%2221244487%22">21244487)</searchLink><br />JAMA. 2013 Nov 27;310(20):2191-4. (PMID: <searchLink fieldCode="PM" term="%2224141714%22">24141714)</searchLink><br />J Clin Epidemiol. 2008 Apr;61(4):344-9. (PMID: <searchLink fieldCode="PM" term="%2218313558%22">18313558)</searchLink><br />JAMA Netw Open. 2020 Jun 1;3(6):e205239. (PMID: <searchLink fieldCode="PM" term="%2232556257%22">32556257)</searchLink><br />Respir Care. 2020 May;65(5):693-704. (PMID: <searchLink fieldCode="PM" term="%2232209710%22">32209710)</searchLink><br />Pediatr Res. 2024 Aug;96(3):595-603. (PMID: <searchLink fieldCode="PM" term="%2236593283%22">36593283)</searchLink><br />J Invest Dermatol. 1998 Aug;111(2):320-6. (PMID: <searchLink fieldCode="PM" term="%229699737%22">9699737)</searchLink><br />Anesth Analg. 2007 Dec;105(6 Suppl):S48-S52. (PMID: <searchLink fieldCode="PM" term="%2218048898%22">18048898)</searchLink><br />Compr Physiol. 2012 Jul;2(3):2203-54. (PMID: <searchLink fieldCode="PM" term="%2223723036%22">23723036)</searchLink><br />Neonatology. 2022;119(2):230-237. (PMID: <searchLink fieldCode="PM" term="%2235124680%22">35124680)</searchLink><br />Am J Perinatol. 2014 May;31(5):435-40. (PMID: <searchLink fieldCode="PM" term="%2223918520%22">23918520)</searchLink><br />Semin Neonatol. 2000 Nov;5(4):273-80. (PMID: <searchLink fieldCode="PM" term="%2211032710%22">11032710)</searchLink><br />Klin Padiatr. 2016 Sep;228(5):245-50. (PMID: <searchLink fieldCode="PM" term="%2227617760%22">27617760)</searchLink><br />Respir Care. 2016 Jan;61(1):90-7. (PMID: <searchLink fieldCode="PM" term="%2226508771%22">26508771)</searchLink><br />Crit Care Med. 2005 Oct;33(10):2203-6. (PMID: <searchLink fieldCode="PM" term="%2216215371%22">16215371)</searchLink><br />Arch Dis Child. 1990 Apr;65(4 Spec No):345-6. (PMID: <searchLink fieldCode="PM" term="%222110802%22">2110802)</searchLink><br />Acta Paediatr. 2020 Apr;109(4):679-687. (PMID: <searchLink fieldCode="PM" term="%2231505053%22">31505053)</searchLink> – Name: GrantInfo Label: Grant Information Group: Grant Data: 031L0303 BMFTR – Name: SubjectMinor Label: Contributed Indexing Group: Data: <i>Keywords: </i>carbon dioxide; neonatal intensive care unit; neonate; premature infants; transcutaneous blood gas monitoring; transcutaneous capnometry – Name: NumberCAS Label: Substance Nomenclature Group: ID Data: 142M471B3J (Carbon Dioxide) – Name: DateEntry Label: Entry Date(s) Group: Date Data: <i>Date Created: </i>20260713 <i>Date Completed: </i>20260713 <i>Latest Revision: </i>20260813 – Name: DateUpdate Label: Update Code Group: Date Data: 20260814 – Name: PubmedCentralID Label: PubMed Central ID Group: ID Data: PMC13358317 – Name: DOI Label: DOI Group: ID Data: 10.1002/ppul.71733 – Name: AN Label: PMID Group: ID Data: 42438310 |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/ppul.71733 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e71733 Subjects: – SubjectFull: Humans Type: general – SubjectFull: Infant, Newborn Type: general – SubjectFull: Female Type: general – SubjectFull: Male Type: general – SubjectFull: Intensive Care Units, Neonatal Type: general – SubjectFull: Infant, Premature Type: general – SubjectFull: Partial Pressure Type: general – SubjectFull: Infant, Extremely Premature Type: general – SubjectFull: Cohort Studies Type: general – SubjectFull: Carbon Dioxide blood Type: general – SubjectFull: Blood Gas Monitoring, Transcutaneous methods Type: general – SubjectFull: Gestational Age Type: general – SubjectFull: Capillaries Type: general Titles: – TitleFull: Correlation of Transcutaneous pCO2 and Capillary pCO2 in Newborn Patients Depending on Gestational Age: A Secondary Data Analysis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Olivier L – PersonEntity: Name: NameFull: Lauterbach Oprea C – PersonEntity: Name: NameFull: Stollenwerk A – PersonEntity: Name: NameFull: Pfannschmidt V – PersonEntity: Name: NameFull: Orlikowsky T – PersonEntity: Name: NameFull: Schoberer M IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: 2026 Jul Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1099-0496 Numbering: – Type: volume Value: 61 – Type: issue Value: 7 Titles: – TitleFull: Pediatric pulmonology Type: main |
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