Academic Journal
Προβολή σε EDS

Challenges and Future Directives of Synthetic Biology in Engineering Plant-Microbe Partnerships for Sustainable Agriculture.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Challenges and Future Directives of Synthetic Biology in Engineering Plant-Microbe Partnerships for Sustainable Agriculture.
Συγγραφείς: Enagbonma BJ; Food Security and Safety Focus Area, Faculty of Natural and Agricultural Sciences, North-West University, Mmabatho, North West Province, South Africa., Molefe-Madlaliso RR; Food Security and Safety Focus Area, Faculty of Natural and Agricultural Sciences, North-West University, Mmabatho, North West Province, South Africa., Adebayo AA; Food Security and Safety Focus Area, Faculty of Natural and Agricultural Sciences, North-West University, Mmabatho, North West Province, South Africa., Oyedoh OP; Food Security and Safety Focus Area, Faculty of Natural and Agricultural Sciences, North-West University, Mmabatho, North West Province, South Africa., Oribhabor GO; Food Security and Safety Focus Area, Faculty of Natural and Agricultural Sciences, North-West University, Mmabatho, North West Province, South Africa., Shittu OE; Food Security and Safety Focus Area, Faculty of Natural and Agricultural Sciences, North-West University, Mmabatho, North West Province, South Africa., Babalola OO; Food Security and Safety Focus Area, Faculty of Natural and Agricultural Sciences, North-West University, Mmabatho, North West Province, South Africa.; Department of Life Sciences, Imperial College London, Silwood Park Campus, Ascot, Berkshire, UK.
Πηγή: Biotechnology and bioengineering [Biotechnol Bioeng] 2026 Jul 12. Date of Electronic Publication: 2026 Jul 12.
Publication Model: Ahead of Print
Τύπος έκδοσης: Journal Article; Review
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Wiley Country of Publication: United States NLM ID: 7502021 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0290 (Electronic) Linking ISSN: 00063592 NLM ISO Abbreviation: Biotechnol Bioeng Subsets: MEDLINE
Imprint Name(s): Publication: <2005->: Hoboken, NJ : Wiley
Original Publication: New York, Wiley.
Περίληψη: Synthetic biology has recently proven to be a valuable tool for enhancing agriculture even in the face of environmental and biological stresses. Understanding the challenges that militate synthetic biology will assist in ensuring safe, stable, and scalable crop production. Thus, we examined the challenges limiting synthetic biology applications in engineering plant-microbe partnerships and highlighted future research directions. Ecological, biological, technical, and regulatory barriers to synthetic biology-driven plant-microbe engineering are the challenges examined in this review. Profound insight into these challenges will lead to a shift toward systems-level approaches that integrate multiomics analyses, predictive modeling, and framework-responsive genetic designs. To completely translate synthetic biology from the laboratory to the field, improved delivery methods, monitoring strategies, and harmonized regulatory frameworks should be encouraged. In addition, the development of robust and controllable microbial chassis should be emphasized.
(© 2026 The Author(s). Biotechnology and Bioengineering published by Wiley Periodicals LLC.)
References: Adamowicz, E. M., J. Flynn, R. C. Hunter, and W. R. Harcombe. 2018. “Cross‐Feeding Modulates Antibiotic Tolerance in Bacterial Communities.” ISME Journal 12, no. 11: 2723–2735.
Adeniji, A., J. Huang, S. Li, X. Lu, and R. Guo. 2025. “Hot Viewpoint on How Soil Texture, Soil Nutrient Availability, and Root Exudates Interact to Shape Microbial Dynamics and Plant Health.” Plant and Soil 511, no. 1: 69–90.
Afanador‐Barajas, L. N., Y. E. Navarro‐Noya, M. L. Luna‐Guido, and L. Dendooven. 2021. “Impact of a Bacterial Consortium on the Soil Bacterial Community Structure and Maize (Zea mays L.) Cultivation.” Scientific Reports 11, no. 1: 13092.
Afridi, M. S., S. Ali, W. C. Terra, B. Ali, M. A. Muneer, and G. Santoyo. 2024. “Harmonizing Traditional and Biotechnological Approaches to Engineer Crop Microbiomes: Enhancing Resilience Optimization.” Biocatalysis and Agricultural Biotechnology 62: 103433.
Aghdam, R., X. Tang, S. Shan, R. Lankau, and C. Solís‐Lemus. 2024. “Human Limits in Machine Learning: Prediction of Potato Yield and Disease Using Soil Microbiome Data.” BMC Bioinformatics 25, no. 1: 366.
Agoussar, A., J. Tremblay, and É. Yergeau. 2025. “Potential Mode of Action of Multispecies Inoculums on Wheat Growth Under Water Stress.” ISME Communications 5, no. 1: ycaf095.
Alamos, S., and P. M. Shih. 2022. “Synthetic Gene Circuits Take Root.” Science 377, no. 6607: 711–712. d.
Alnahhas, R. N., J. J. Winkle, A. J. Hirning, et al. 2019. “Spatiotemporal Dynamics of Synthetic Microbial Consortia in Microfluidic Devices.” ACS Synthetic Biology 8, no. 9: 2051–2058.
Ambaru, B., R. Manvitha, and R. Madas. 2025. “Synergistic Integration of Remote Sensing and Soil Metagenomics Data: Advancing Precision Agriculture Through Interdisciplinary Approaches.” Frontiers in Sustainable Food Systems 8: 1499973.
Amer, M. A., and S. M. Hamed. 2025. “Genomic Prediction of Phytase Potential and Stress Tolerance in Maize‐Associated Plant Growth‐Promoting Rhizobacterium Enterobacter cloacae Mz49.” AMB Express 15, no. 1: 180.
Ando, H., S. Lemire, D. P. Pires, and T. K. Lu. 2015. “Engineering Modular Viral Scaffolds for Targeted Bacterial Population Editing.” Cell Systems 1, no. 3: 187–196.
Anyshchenko, A., and J. Yarnold. 2021. “From ‘Mad Cow’ Crisis to Synthetic Biology: Challenges to EU Regulation of GMOs Beyond the European Context.” International Environmental Agreements: Politics, Law and Economics 21, no. 3: 391–404.
Armanhi, J. S. L., R. S. C. de Souza, B. B. Biazotti, J. E. C. T. Yassitepe, and P. Arruda. 2021. “Modulating Drought Stress Response of Maize by a Synthetic Bacterial Community.” Frontiers in Microbiology 12: 747541.
Avery, M. B., R. G. Dalton, and K. F. Emma. 2026. “Emerging Governance Considerations for the Deployment of Genetically Engineered Microbes.” Current Opinion in Microbiology 89: 102685.
Babalola, O. O., A. E. Fadiji, B. J. Enagbonma, E. T. Alori, M. S. Ayilara, and A. S. Ayangbenro. 2020. “The Nexus Between Plant and Plant Microbiome: Revelation of the Networking Strategies.” Frontiers in Microbiology 11: 548037.
Babalola, O. O., R. Molefe, and A. Amoo. 2021. “Revealing the Active Microbiome Connected With the Rhizosphere Soil of Maize Plants in Ventersdorp, South Africa.” Biodiversity Data Journal 9: e60245.
Bai, W., C. Li, W. Li, et al. 2024. “Machine Learning Assists Prediction of Genes Responsible for Plant Specialized Metabolite Biosynthesis by Integrating Multiomics Data.” BMC Genomics 25, no. 1: 418.
Bai, Y., X. Liu, and I. T. Baldwin. 2024. “Using Synthetic Biology to Understand the Function of Plant Specialized Metabolites.” Annual Review of Plant Biology 75, no. 1: 629–653.
Bandopadhyay, S., X. Li, A. W. Bowsher, R. L. Last, and A. Shade. 2024. “Disentangling Plant‐ and Environment‐Mediated Drivers of Active Rhizosphere Bacterial Community Dynamics During Short‐Term Drought.” Nature Communications 15, no. 1: 6347.
Bao, H., Y. Wang, H. Li, et al. 2025. “The Rhizobial Effector NopT Targets Nod Factor Receptors to Regulate Symbiosis in Lotus japonicus.” eLife 13: RP97196.
Becker, J. W., S. L. Hogle, K. Rosendo, and S. W. Chisholm. 2019. “Coculture and Biogeography of Prochlorococcus and SAR11.” ISME Journal 13, no. 6: 1506–1519.
Behrens, S., A. Kappler, and M. Obst. 2012. “Linking Environmental Processes to the In Situ Functioning of Microorganisms by High‐Resolution Secondary Ion Mass Spectrometry (NanoSIMS) and Scanning Transmission X‐Ray Microscopy (STXM).” Environmental Microbiology 14, no. 11: 2851–2869.
Benmrid, B., M. Idbella, G. Bonanomi, et al. 2025. “Drought‐Tolerant Rhizobacterial Consortia With Diverse Plant Growth Promoting Traits Enhance Wheat and Faba Bean Growth Under Water and Low‐P Availability Promising Multitraits.” BMC Microbiology 25, no. 1: 771.
Bibek, L., D. Okram Ricky, D. Rinjumoni, et al. 2025. “Plant–Microbe Interactions: PGPM as Microbial Inoculants/Biofertilizers for Sustaining Crop Productivity and Soil Fertility.” Current Research in Microbial Sciences 8: 100333.
Björklöf, K., R. Sen, and K. Jørgensen. 2003. “Maintenance and Impacts of an Inoculated mer/luc‐Tagged Pseudomonas fluorescens on Microbial Communities in Birch Rhizospheres Developed on Humus and Peat.” Microbial Ecology 45, no. 1: 39–52.
Blount, B. A., T. Weenink, and T. Ellis. 2012. “Construction of Synthetic Regulatory Networks in Yeast.” FEBS Letters 586, no. 15: 2112–2121.
Brophy, J. A. N., K. J. Magallon, L. Duan, et al. 2022. “Synthetic Genetic Circuits as a Means of Reprogramming Plant Roots.” Science 377, no. 6607: 747–751.
Brophy, J. A. N., A. J. Triassi, B. L. Adams, et al. 2018. “Engineered Integrative and Conjugative Elements for Efficient and Inducible DNA Transfer to Undomesticated Bacteria.” Nature Microbiology 3, no. 9: 1043–1053.
Bulgarelli, D., K. Schlaeppi, S. Spaepen, E. V. L. Van Themaat, and P. Schulze‐Lefert. 2013. “Structure and Functions of the Bacterial Microbiota of Plants.” Annual Review of Plant Biology 64, no. 1: 807–838.
Busato, S., M. Gordon, M. Chaudhari, et al. 2023. “Compositionality, Sparsity, Spurious Heterogeneity, and Other Data‐Driven Challenges for Machine Learning Algorithms Within Plant Microbiome Studies.” Current Opinion in Plant Biology 71: 102326.
Cadot, S., H. Guan, M. Bigalke, et al. 2021. “Specific and Conserved Patterns of Microbiota‐Structuring by Maize Benzoxazinoids in the Field.” Microbiome 9, no. 1: 103.
Cangioli, L., S. Tabacchioni, A. Visca, et al. 2024. “Genome Insights Into Beneficial Microbial Strains Composing SIMBA Microbial Consortia Applied as Biofertilizers for Maize, Wheat and Tomato.” Microorganisms 12, no. 12: 2562.
Carlström, C. I., C. M. Field, M. Bortfeld‐Miller, B. Müller, S. Sunagawa, and J. A. Vorholt. 2019. “Synthetic Microbiota Reveal Priority Effects and Keystone Strains in the Arabidopsis Phyllosphere.” Nature Ecology & Evolution 3, no. 10: 1445–1454.
Carter, S. R., M. Rodemeyer, M. S. Garfinkel, and R. M. Friedman. 2014. Synthetic Biology and the U.S. Biotechnology Regulatory System: Challenges and Options. J. Craig Venter Institute.
Casey, J. R., M. W. Lomas, J. Mandecki, and D. E. Walker. 2007. “Prochlorococcus Contributes to New Production in the Sargasso Sea Deep Chlorophyll Maximum.” Geophysical Research Letters 34, no. 10: L10604.
Cernava, T. 2024. “Coming of Age for Microbiome Gene Breeding in Plants.” Nature Communications 15, no. 1: 6623.
Chaudhary, D. K., A. Khulan, and J. Kim. 2019. “Development of a Novel Cultivation Technique for Uncultured Soil Bacteria.” Scientific Reports 9, no. 1: 6666.
Chauhan, J., S. Solanki, and M. Yadav. 2025. “Global Food Security and Sustainable Development: An Overview.” In Forage Crops in the Bioenergy Revolution, edited by R. K. Singhal, Indu, A. El Sabagh, and K. K. Dwivedi. Springer.
Chemla, Y., C. J. Sweeney, C. A. Wozniak, and C. A. Voigt. 2025. “Design and Regulation of Engineered Bacteria for Environmental Release.” Nature Microbiology 10, no. 2: 281–300.
Chen, Y., Y. Fu, Y. Xia, et al. 2024. “Trichoderma‐Secreted Anthranilic Acid Promotes Lateral Root Development via Auxin Signaling and Rbohf‐Induced Endodermal Cell Wall Remodeling.” Cell Reports 43, no. 4: 114030.
Chen, C., M. Wang, J. Zhu, et al. 2022. “Long‐Term Effect of Epigenetic Modification in Plant–Microbe Interactions: Modification of DNA Methylation Induced by Plant Growth‐Promoting Bacteria Mediates Promotion Process.” Microbiome 10, no. 1: 36.
Cheng, Y., X. Gao, H. He, X. Zhang, R. Wang, and J. Liu. 2022. “Dual RNA Sequencing Analysis of Bacillus amyloliquefaciens and Sclerotinia sclerotiorum During Infection of Soybean Seedlings by S. sclerotiorum Unveils Antagonistic Interactions.” Frontiers in Microbiology 13: 924313.
Chesneau, G., J. Herpell, R. Garrido‐Oter, and S. Hacquard. 2025. “From Synthetic Communities to Synthetic Ecosystems: Exploring Causalities in Plant–Microbe–Environment Interactions.” New Phytologist 245, no. 2: 496–502.
Clauer, P., A. X. Nou, T. Toth, et al. 2026. “Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications.” Chemical Reviews 126, no. 2: 895–1109.
Coker, J., K. Zhalnina, C. Marotz, et al. 2022. “A Reproducible and Tunable Synthetic Soil Microbial Community Provides New Insights Into Microbial Ecology.” mSystems 7, no. 6: e00951‐22.
Copeland, C., P. Schulze‐Lefert, and K. W. Ma. 2025. “Potential and Challenges for Application of Microbiomes in Agriculture.” Plant Cell 37, no. 8: koaf185.
Coutinho, R. M., T. Klauschies, and U. Gaedke. 2016. “Bimodal Trait Distributions With Large Variances Question the Reliability of Trait‐Based Aggregate Models.” Theoretical Ecology 9, no. 4: 389–408.
Coyte, K. Z., J. Schluter, and K. R. Foster. 2015. “The Ecology of the Microbiome: Networks, Competition, and Stability.” Science 350, no. 6261: 663–666.
Cui, Y., Y. Tao, Y. Luo, et al. 2025. “Harnessing Synthetic Microbial Communities for Sustainable Agriculture: Enhancing Soil Health and Crop Yields.” Critical Reviews in Environmental Science and Technology 55, no. 19: 1479–1505.
D'Souza, G., and C. Kost. 2016. “Experimental Evolution of Metabolic Dependency in Bacteria.” PLoS Genetics 12, no. 11: e1006364.
De la Vega‐Camarillo, E., J. Arreola‐Vargas, S. Antony‐Babu, S. K. Mathur, J. A. Santos, and W. B. Shim. 2025. “Machine Learning‐Guided Synthetic Microbial Communities Enable Functional and Sustainable Degradation of Persistent Environmental Pollutants.” Environmental Science & Technology 160, no. 18: 13500–13519.
De la Vega‐Camarillo, E., J. Sotelo‐Aguilar, B. Rios‐Galicia, et al. 2023. “Promotion of the Growth and Yield of Zea mays by Synthetic Microbial Communities From Jala Maize.” Frontiers in Microbiology 14: 1167839.
Deng, Z., J. Zhang, J. Li, and X. Zhang. 2021. “Application of Deep Learning in Plant–Microbiota Association Analysis.” Frontiers in Genetics 12: 697090.
Díaz‐García, L., S. Huang, C. Spröer, et al. 2021. “Dilution‐to‐Stimulation/Extinction Method: A Combination Enrichment Strategy to Develop a Minimal and Versatile Lignocellulolytic Bacterial Consortium.” Applied and Environmental Microbiology 87, no. 2: e02427‐02420.
Druckenbrod, D. L., H. H. Shugart, and I. Davies. 2005. “Spatial Pattern and Process in Forest Stands Within the Virginia Piedmont.” Journal of Vegetation Science 16, no. 1: 37–48.
Dubey, A., M. A. Malla, S. R. Vimal, A. Kumar, S. M. Prasad, and M. L. Khan. 2025. “Plant‐Microbiome Engineering: Synergistic Microbial Partners for Crop Health and Sustainability.” Plant Growth Regulation 105: 1825–1839.
Duhan, P., B. Gupta, M. Ahmed, and P. Bansal. 2025. “Gut Microbiome Engineering With Probiotics: Current Trends and Future Directions.” Discover Applied Sciences 7, no. 11: 1354.
Dukovski, I., D. Bajić, J. M. Chacón, et al. 2020. “Computation of Microbial Ecosystems in Time and Space (COMETS): An Open Source Collaborative Platform for Modeling Ecosystems Metabolism.” Preprint, arXiv: 200901734.
Dundas, C. M., and J. R. Dinneny. 2022. “Genetic Circuit Design in Rhizobacteria.” BioDesign Research 2022: 9858049.
Duraj‐Thatte, A. M., A. Manjula‐Basavanna, J. Rutledge, et al. 2021. “Programmable Microbial Ink for 3D Printing of Living Materials Produced From Genetically Engineered Protein Nanofibers.” Nature Communications 12, no. 1: 6600.
Durán, P., T. J. Ellis, T. Thiergart, J. Ågren, and S. Hacquard. 2022. “Climate Drives Rhizosphere Microbiome Variation and Divergent Selection Between Geographically Distant Arabidopsis Populations.” New Phytologist 236, no. 2: 608–621.
Efthimiadou, A., N. Katsenios, S. Chanioti, M. Giannoglou, N. Djordjevic, and G. Katsaros. 2020. “Effect of Foliar and Soil Application of Plant Growth Promoting Bacteria on Growth, Physiology, Yield and Seed Quality of Maize under Mediterranean Conditions.” Scientific Reports 10, no. 1: 21060.
Emmenegger, B., J. Massoni, C. M. Pestalozzi, M. Bortfeld‐Miller, B. A. Maier, and J. A. Vorholt. 2023. “Identifying Microbiota Community Patterns Important for Plant Protection Using Synthetic Communities and Machine Learning.” Nature Communications 14, no. 1: 7983.
Enagbonma, B. J., and O. O. Babalola. 2019. “Environmental Sustainability: A Review of Termite Mound Soil Material and Its Bacteria.” Sustainability 11, no. 14: 3847.
Enagbonma, B. J., A. E. Fadiji, A. S. Ayangbenro, and O. O. Babalola. 2023. “Communication Between Plants and Rhizosphere Microbiome: Exploring the Root Microbiome for Sustainable Agriculture.” Microorganisms 11, no. 8: 2003.
Enagbonma, B. J., A. E. Fadiji, and O. O. Babalola. 2024. “Anthropogenic Fertilization Influences a Shift in Barley Rhizosphere Microbial Communities.” PeerJ 12: e17303.
Enagbonma, B. J., E. E. Imade, O. P. Oyedoh, O. Osarenotor, O. O. Babalola, and D. M. Modise. 2025. “Future Directions in Rhizobacteria Research and Application.” Nile Journal of Engineering and Applied Science 3, no. 1: 16–22.
Endress, M.‐G., F. Dehghani, S. Blagodatsky, T. Reitz, S. Schlüter, and E. Blagodatskaya. 2024. “Spatial Substrate Heterogeneity Limits Microbial Growth as Revealed by the Joint Experimental Quantification and Modeling of Carbon and Heat Fluxes.” Soil Biology and Biochemistry 197: 109509.
English, M., L. L. Nalley, B. R. McFadden, A. Durand‐Morat, A. Adetoyinbo, and L. Madubanya. 2026. “Differentiating GM Technologies: South African Consumer Perceptions of Water Efficient Maize for Africa.” NPJ Sustainable Agriculture 4, no. 1: 34.
Escoriza, M. F., J. M. Vanbriesen, S. Stewart, and J. Maier. 2006. “Studying Bacterial Metabolic States Using Raman Spectroscopy.” Applied Spectroscopy 60, no. 9: 971–976.
Eureka. 2025. “Regulatory Pathways for Synthetic Biology Streamlining. Unlock AI‐Driven, Actionable R&D Insights for Your Next Breakthrough.” Vol 2026. Patsnap Eureka Blog, September 19. https://eureka.patsnap.com/report‐regulatory‐pathways‐for‐synthetic‐biology‐streamlining?utm_source=chatgpt.com.
Fadiji, A. E., A. Adeniji, A. A. Lanrewaju, et al. 2025. “Key Challenges in Plant Microbiome Research in the Next Decade.” Microorganisms 13, no. 11: 2546.
Fagorzi, C., I. Passeri, L. Cangioli, F. Vaccaro, and A. Mengoni. 2023. “When Biodiversity Preservation Meets Biotechnology: The Challenge of Developing Synthetic Microbiota for Resilient Sustainable Crop Production.” Journal of Sustainable Agriculture and Environment 2, no. 1: 5–15.
Fatehi, L., and R. F. Hall. 2015. “Synthetic Biology in the FDA Realm: Toward Productive Oversight Assessment.” Food and Drug Law Journal 70: 339–369.
Faure, M., and M. Jiang. 2022. “Financial Security Mechanisms to Cover Biodiversity Damage Resulting From the Use of Genetically Modified Organisms.” Emory International Law Review 37: 561.
Ferioun, M., S. Bouhraoua, D. Belahcen, et al. 2024. “PGPR Consortia Enhance Growth and Yield in Barley Cultivars Subjected to Severe Drought Stress and Subsequent Recovery.” Rhizosphere 31: 100926.
Fitzpatrick, C. R., J. Copeland, P. W. Wang, D. S. Guttman, P. M. Kotanen, and M. T. J. Johnson. 2018. “Assembly and Ecological Function of the Root Microbiome Across Angiosperm Plant Species.” Proceedings of the National Academy of Sciences 115, no. 6: E1157–E1165.
Fonseca‐García, C., D. Pettinga, A. Wilson, et al. 2024. “Defined Synthetic Microbial Communities Colonize and Benefit Field‐Grown Sorghum.” ISME Journal 18, no. 1: wrae126.
Forry, S. P., S. L. Servetas, J. G. Kralj, et al. 2024. “Variability and Bias in Microbiome Metagenomic Sequencing: An Interlaboratory Study Comparing Experimental Protocols.” Scientific Reports 14, no. 1: 9785.
Francioli, D., I. D. Kampouris, T. Kuhl‐Nagel, et al. 2025. “Microbial Inoculants Modulate the Rhizosphere Microbiome, Alleviate Plant Stress Responses, and Enhance Maize Growth at Field Scale.” Genome Biology 26, no. 1: 148.
Fritts, R. K., A. L. McCully, and J. B. McKinlay. 2021. “Extracellular Metabolism Sets the Table for Microbial Cross‐Feeding.” Microbiology and Molecular Biology Reviews 85, no. 1. https://doi.org/10.1128/mmbr.00135‐20.
Fujiwara, F., K. Miyazawa, N. Nihei, and Y. Ichihashi. 2023. “Agroecosystem Engineering Extended From Plant–Microbe Interactions Revealed by Multiomics Data.” Bioscience, Biotechnology, and Biochemistry 87, no. 1: 21–27.
Gao, J.‐P., P. Xu, M. Wang, et al. 2021. “Nod Factor Receptor Complex Phosphorylates GmGEF2 to Stimulate ROP Signaling During Nodulation.” Current Biology 31, no. 16: 3538–3550.e5.
Garcia Arredondo, M., W. Kew, and R. Chu, et al. 2024. “Differential Exudation Creates Biogeochemically Distinct Microenvironments During Rhizosphere Evolution.” Environmental Science & Technology 58, no. 42: 18713–18722.
Ge, A.‐H., and E. Wang. 2025. “Exploring the Plant Microbiome: A Pathway to Climate‐Smart Crops.” Cell 188, no. 6: 1469–1485.
Getahun, S., H. Kefale, and Y. Gelaye. 2024. “Application of Precision Agriculture Technologies for Sustainable Crop Production and Environmental Sustainability: A Systematic Review.” Scientific World Journal 2024, no. 1: 2126734.
Gillett, D. L., M. Selinidis, T. Seamons, et al. 2025. “A Roadmap to Understanding and Anticipating Microbial Gene Transfer in Soil Communities.” Microbiology and Molecular Biology Reviews 89, no. 2: e00225‐00224.
Gilmore, S. P., T. S. Lankiewicz, S. E. Wilken, et al. 2019. “Top‐Down Enrichment Guides in Formation of Synthetic Microbial Consortia for Biomass Degradation.” ACS Synthetic Biology 8, no. 9: 2174–2185.
Ginatt, A. A., M. Berihu, E. Castel, et al. 2024. “A Metabolic Modeling‐Based Framework for Predicting Trophic Dependencies in Native Rhizobiomes of Crop Plants.” eLife 13: RP94558.
Giri, S., S. Waschina, C. Kaleta, and C. Kost. 2019. “Defining Division of Labor in Microbial Communities.” Journal of Molecular Biology 431, no. 23: 4712–4731.
Goicoechea, N. 2020. “Mycorrhizal Fungi as Bioprotectors of Crops Against Verticillium Wilt—A Hypothetical Scenario Under Changing Environmental Conditions.” Plants 9, no. 11: 1468.
Gonçalves, O. S., C. J. Creevey, and M. F. Santana. 2023. “Designing a Synthetic Microbial Community Through Genome Metabolic Modeling to Enhance Plant–Microbe Interaction.” Environmental Microbiome 18, no. 1: 81.
Goyal, A., L. S. Bittleston, G. E. Leventhal, L. Lu, and O. X. Cordero. 2022. “Interactions Between Strains Govern the Eco‐Evolutionary Dynamics of Microbial Communities.” eLife 11: e74987.
Groff‐Vindman, C. S., B. D. Trump, C. L. Cummings, et al. 2025. “The Convergence of AI and Synthetic Biology: The Looming Deluge.” npj Biomedical Innovations 2, no. 1: 20.
Guiziou, S., C. J. Maranas, J. C. Chu, and J. L. Nemhauser. 2023. “An Integrase Toolbox to Record Gene‐Expression During Plant Development.” Nature Communications 14, no. 1: 1844.
Guo, Y., Y. Zhao, and X. Tang, et al. 2021. “Deciphering Bacterial Social Traits via Diffusible Signal Factor (DSF)‐Mediated Public Goods in an Anammox Community.” Water Research 191: 116802.
Gupta, A., I. M. B. Reizman, C. R. Reisch, and K. L. J. Prather. 2017. “Dynamic Regulation of Metabolic Flux in Engineered Bacteria Using a Pathway‐Independent Quorum‐Sensing Circuit.” Nature Biotechnology 35, no. 3: 273–279.
Gutiérrez, C. F., N. Rodríguez‐Romero, S. Egan, E. Holmes, and J. Sanabria. 2022. “Exploiting the Potential of Bioreactors for Creating Spatial Organization in the Soil Microbiome: A Strategy for Increasing Sustainable Agricultural Practices.” Microorganisms 10, no. 7: 1464.
Habibi, L. N., T. Matsui, and T. S. T. Tanaka. 2024. “Critical Evaluation of the Effects of a Cross‐Validation Strategy and Machine Learning Optimization on the Prediction Accuracy and Transferability of a Soybean Yield Prediction Model Using UAV‐Based Remote Sensing.” Journal of Agriculture and Food Research 16: 101096.
Hammarlund, S. P., J. M. Chacón, and W. R. Harcombe. 2019. “A Shared Limiting Resource Leads to Competitive Exclusion in a Cross‐Feeding System.” Environmental Microbiology 21, no. 2: 759–771.
Hamza, R., A. Nadia, R. Sadia, et al. 2023. “Genetically Engineered Microorganisms for Environmental Remediation.” Chemosphere 310: 136751.
Han, L. 2024. “Optimizing Synthetic Microbial Communities for Sustainable Agriculture: Design, Functionality, and Field Performance.” Molecular Microbiology Research 14, no. 1: 31–38.
Han, S.‐W., and Y. Yoshikuni. 2022. “Microbiome Engineering for Sustainable Agriculture: Using Synthetic Biology to Enhance Nitrogen Metabolism in Plant‐Associated Microbes.” Current Opinion in Microbiology 68: 102172.
Hanif, M. S., M. Tayyab, E. H. Baillo, M. M. Islam, W. Islam, and X. Li. 2024. “Plant Microbiome Technology for Sustainable Agriculture.” Frontiers in Microbiology 15: 1500260.
Hannula, S. E., R. Heinen, M. Huberty, et al. 2021. “Persistence of Plant‐Mediated Microbial Soil Legacy Effects in Soil and Inside Roots.” Nature Communications 12, no. 1: 5686.
Harcombe, W. R., W. J. Riehl, I. Dukovski, et al. 2014. “Metabolic Resource Allocation in Individual Microbes Determines Ecosystem Interactions and Spatial Dynamics.” Cell Reports 7, no. 4: 1104–1115.
Haskett, T. L., P. Paramasivan, M. D. Mendes, et al. 2022. “Engineered Plant Control of Associative Nitrogen Fixation.” Proceedings of the National Academy of Sciences 119, no. 16: e2117465119.
Herath Dissanayakalage, S. S., J. Kaur, T. Li, A. M. Dimech, and T. I. Sawbridge. 2025. “Seed‐Derived Synthetic Microbial Communities (SynComs) From Medicago Wild Relatives Modulate Early Plant Microbiome Assembly and Phenotypic Traits in Lucerne (Medicago sativa L.).” Microorganisms 13, no. 9: 2114.
Hernández‐García, J. A., J. S. Bernal, S. Antony‐Babu, L. Villa‐Tanaca, C. Hernández‐Rodríguez, and E. Dela‐Vega‐Camarillo. 2025. “Teosinte‐Derived SynCom and Precision Biofertilization Modulate the Maize Microbiome, Enhancing Growth, Yield, and Soil Functionality in a Mexican Field.” Frontiers in Microbiology 16: 1534327.
Hett, J., T. F. Döring, A. Bevivino, and D. Neuhoff. 2023. “Impact of Microbial Consortia on Organic Maize in a Temperate Climate Varies With Environment but Not With Fertilization.” European Journal of Agronomy 144: 126743.
Huang, W. E., K. Stoecker, R. Griffiths, et al. 2007. “Raman‐FISH: Combining Stable‐Isotope Raman Spectroscopy and Fluorescence In Situ Hybridization for the Single Cell Analysis of Identity and Function.” Environmental Microbiology 9, no. 8: 1878–1889.
Huang, X., J. Wang, K. Dumack, et al. 2024. “Temperature‐Dependent Trophic Associations Modulate Soil Bacterial Communities Along Latitudinal Gradients.” ISME Journal 18, no. 1: 1751–7362.
Iliäœić, R. M., R. N. Pivić, Z. S. Dinić, D. S. Latković, S. A. Vlajić, and D. L. Jošić. 2017. “The Enhancement of Soybean Growth and Yield in a Field Trial Through Introduction of Mixtures of Bradyrhizobium japonicum, Bacillus sp. and Pseudomonas chlororaphis.” Notulae Scientia Biologicae 9, no. 2: 274–279.
Ishizawa, H., M. Tada, M. Kuroda, D. Inoue, H. Futamata, and M. Ike. 2020. “Synthetic Bacterial Community of Duckweed: A Simple and Stable System to Study Plant–Microbe Interactions.” Microbes and Environments 35, no. 4: ME20112.
Jabborova, D., A. Kannepalli, K. Davranov, et al. 2021. “Coinoculation of Rhizobacteria Promotes Growth, Yield, and Nutrient Contents in Soybean and Improves Soil Enzymes and Nutrients Under Drought Conditions.” Scientific Reports 11, no. 1: 22081.
Jain, A., S. Sarsaiya, R. Singh, Q. Gong, Q. Wu, and J. Shi. 2024. “Omics Approaches in Understanding the Benefits of Plant–Microbe Interactions.” Frontiers in Microbiology 15: 1391059.
Jiang, Y., R. Wu, W. Zhang, F. Xin, and M. Jiang. 2023. “Construction of Stable Microbial Consortia for Effective Biochemical Synthesis.” Trends in Biotechnology 41, no. 11: 1430–1441.
Jochum, M. D., K. L. McWilliams, E. A. Pierson, and Y.‐K. Jo. 2019. “Host‐Mediated Microbiome Engineering (HMME) of Drought Tolerance in the Wheat Rhizosphere.” PLoS One 14, no. 12: e0225933.
Joint, I., K. Tait, M. E. Callow, et al. 2002. “Cell‐to‐Cell Communication Across the Prokaryote‐Eukaryote Boundary.” Science 298, no. 5596: 1207.
Karimi, M. A., M. Paryan, G. Behrouzian Fard, H. Sadeghian, H. Zarrinfar, and M. Hosseini Bafghi. 2026. “Challenges and Opportunities in the Application of CRISPR‐Cas9: A Review on Genomic Editing and Therapeutic Potentials.” Medical Principles and Practice 35, no. 1: 1–17.
Karkaria, B. D., A. J. H. Fedorec, and C. P. Barnes. 2021. “Automated Design of Synthetic Microbial Communities.” Nature Communications 12, no. 1: 672.
Kaur, S., E. Egidi, Z. Qiu, et al. 2022. “Synthetic Community Improves Crop Performance and Alters Rhizosphere Microbial Communities.” Journal of Sustainable Agriculture and Environment 1, no. 2: 118–131.
Kawasaki, A., P. G. Dennis, C. Forstner, et al. 2021. “Manipulating Exudate Composition From Root Apices Shapes the Microbiome Throughout the Root System.” Plant Physiology 187, no. 4: 2279–2295.
Keiblinger, K. M., S. Fuchs, S. Zechmeister‐Boltenstern, and K. Riedel. 2016. “Soil and Leaf Litter Metaproteomics—A Brief Guideline From Sampling to Understanding.” FEMS Microbiology Ecology 92, no. 11: fiw180.
Khaledi, F., H. Balouchi, M. Movahhedi Dehnavi, and A. Salehi. 2025. “Enhancing Maize Yield, Water Use Efficiency, and Zn Content Under Drought Stress by Applying Zn‐Solubilising Bacteria.” Agricultural Water Management 308: 109313.
Kim, H. J., J. Q. Boedicker, J. W. Choi, and R. F. Ismagilov. 2008. “Defined Spatial Structure Stabilizes a Synthetic Multispecies Bacterial Community.” Proceedings of the National Academy of Sciences 105, no. 47: 18188–18193.
Kim, H., J. Lee, Y. Cho, H. Kim, H. Kim, and B. H. Sung. 2025. “Governing Synthetic Biology: A Coevolutionary Framework for Sustainable Innovation.” Journal of Microbiology and Biotechnology 35: e2508001.
Kobae, Y., H. Kameoka, Y. Sugimura, et al. 2018. “Strigolactone Biosynthesis Genes of Rice Are Required for the Punctual Entry of Arbuscular Mycorrhizal Fungi Into the Roots.” Plant and Cell Physiology 59, no. 3: 544–553.
Kong, W., D. R. Meldgin, J. J. Collins, and T. Lu. 2018. “Designing Microbial Consortia With Defined Social Interactions.” Nature Chemical Biology 14, no. 8: 821–829.
König, S., H.‐J. Vogel, H. Harms, and A. Worrich. 2020. “Physical, Chemical and Biological Effects on Soil Bacterial Dynamics in Microscale Models.” Frontiers in Ecology and Evolution 8: 53.
Krause, S., X. Le Roux, P. A. Niklaus, et al. 2014. “Trait‐Based Approaches for Understanding Microbial Biodiversity and Ecosystem Functioning.” Frontiers in Microbiology 5: 251.
Krieger, A. G., J. Zhang, and X. N. Lin. 2021. “Temperature Regulation as a Tool to Program Synthetic Microbial Community Composition.” Biotechnology and Bioengineering 118, no. 3: 1381–1392.
Kumar, R., P. Swapnil, M. Meena, S. Selpair, and B. G. Yadav. 2022. “Plant Growth‐Promoting Rhizobacteria (PGPR): Approaches to Alleviate Abiotic Stresses for Enhancement of Growth and Development of Medicinal Plants.” Sustainability 14, no. 23: 15514.
Kurt, P. O. 2025. “Field‐Based Evaluation of Multistrain PGPR to Improve Zea mays Yield and Soil Nutrient Dynamics in Semiarid of Türkiye.” Scientific Reports 15, no. 1: 22553.
Kwan, B. D., B. Seligmann, T.‐D. Nguyen, J. Franke, and T.‐T. T. Dang. 2023. “Leveraging Synthetic Biology and Metabolic Engineering to Overcome Obstacles in Plant Pathway Elucidation.” Current Opinion in Plant Biology 71: 102330.
Lau, S. E., W. F. A. Teo, E. Y. Teoh, and B. C. Tan. 2022. “Microbiome Engineering and Plant Biostimulants for Sustainable Crop Improvement and Mitigation of Biotic and Abiotic Stresses.” Discover Food 2, no. 1: 9.
Lee, J. A., A. C. Baugh, N. J. Shevalier, B. Strand, S. Stolyar, and C. J. Marx. 2021. “Cross‐Feeding of a Toxic Metabolite in a Synthetic Lignocellulose‐Degrading Microbial Community.” Microorganisms 9, no. 2: 321.
Levy, A., J. M. Conway, J. L. Dangl, and T. Woyke. 2018. “Elucidating Bacterial Gene Functions in the Plant Microbiome.” Cell Host & Microbe 24, no. 4: 475–485.
Li, H., X. Cui, Y. Sun, P. Zheng, L. Wang, and X. Shi. 2025. “Advances in Microbial Remediation of Heavy Metal‐Contaminated Soils: Mechanisms, Synergistic Technologies, Field Applications and Future Perspectives.” Toxics 13, no. 12: 1069.
Li, Q., Y. Xing, X. Fu, et al. 2021. “Biochemical Mechanisms of Rhizospheric Bacillus subtilis‐Facilitated Phytoextraction by Alfalfa Under Cadmium Stress–Microbial Diversity and Metabolomics Analyses.” Ecotoxicology and Environmental Safety 212: 112016.
Li, M., R. Yang, Q. Bai, et al. 2026. “Manipulating Root‐Associated Microbiomes to Boost Drought Resistance in Dryland Winter Wheat With Streptomyces pactum Act12.” BMC Microbiology 26, no. 1: 249.
Li, E., H. Zhang, H. Jiang, et al. 2021. “Experimental‐Evolution‐Driven Identification of Arabidopsis Rhizosphere Competence Genes in Pseudomonas protegens.” mBio 12, no. 3: 10.
Liang, Y., A. Ma, and G. Zhuang. 2022. “Construction of Environmental Synthetic Microbial Consortia: Based on Engineering and Ecological Principles.” Frontiers in Microbiology 13: 829717.
Liang, X., S. Yu, Y. Ju, Y. Wang, and D. Yin. 2025. “Integrated Management Practices Foster Soil Health, Productivity, and Agroecosystem Resilience.” Agronomy 15, no. 8: 1816.
Liao, C., T. Wang, S. Maslov, and J. B. Xavier. 2020. “Modeling Microbial Cross‐Feeding at Intermediate Scale Portrays Community Dynamics and Species Coexistence.” PLoS Computational Biology 16, no. 8: e1008135.
Liu, Y., L. Cao, H. Tan, and R. Zhang. 2017. “Surface Display of ACC Deaminase on Endophytic Enterobacteriaceae Strains to Increase Saline Resistance of Host Rice Sprouts by Regulating Plant Ethylene Synthesis.” Microbial Cell Factories 16, no. 1: 214.
Liu, Y., B. Jia, Y. Ren, et al. 2025. “Bacterial Social Interactions in Synthetic Bacillus Consortia Enhance Plant Growth.” iMeta 4: e70053.
Liu, Y., D. Patko, I. Engelhardt, et al. 2021. “Plant–Environment Microscopy Tracks Interactions of Bacillus subtilis With Plant Roots Across the Entire Rhizosphere.” Proceedings of the National Academy of Sciences 118, no. 48: e2109176118.
Lloyd, J. P., F. Ly, P. Gong, et al. 2022. “Synthetic Memory Circuits for Stable Cell Reprogramming in Plants.” Nature Biotechnology 40, no. 12: 1862–1872.
Lloyd, K. G., A. D. Steen, J. Ladau, J. Yin, and L. Crosby. 2018. “Phylogenetically Novel Uncultured Microbial Cells Dominate Earth Microbiomes.” mSystems 3, no. 5: 10–1128.
Ma, Y., H. Wang, Y. Kang, and T. Wen. 2025. “Small Molecule Metabolites Drive Plant Rhizosphere Microbial Community Assembly Patterns.” Frontiers in Microbiology 16: 1503537.
Macedo, G., A. K. Olesen, L. Maccario, et al. 2022. “Horizontal Gene Transfer of an incp1 Plasmid to Soil Bacterial Community Introduced by Escherichia coli Through Manure Amendment in Soil Microcosms.” Environmental Science & Technology 56, no. 16: 11398–11408.
Magaisa, A., E. Ngadze, T. P. Mamphogoro, M. P. Moyo, and C. N. Kamutando. 2025. “Exploring the Role of Rhizobacteria in Sorghum Bicolor Adaptation to Combined Drought and Heat Stress.” Microorganisms 13, no. 11: 2454.
Mallick, H., S. Ma, E. A. Franzosa, T. Vatanen, X. C. Morgan, and C. Huttenhower. 2017. “Experimental Design and Quantitative Analysis of Microbial Community Multiomics.” Genome Biology 18, no. 1: 228.
Mandel, G. N., and G. E. Marchant. 2014. “The Living Regulatory Challenges of Synthetic Biology.” Iowa Law Review 100: 155.
Marchand, N., and C. H. Collins. 2016. “Synthetic Quorum Sensing and Cell–Cell Communication in Gram‐Positive Bacillus megaterium.” ACS Synthetic Biology 5, no. 7: 597–606.
Marden, E., D. Kulkarni, E. M. McMahon, M. S. Rowand, and K. Verzijden. 2023. “Regulatory Frameworks Applicable to Food Products of Genome Editing and Synthetic Biology in the United States, Canada, and the European Union.” In Genomics and the Global Bioeconomy, 255–285. Elsevier.
Martiny, J. B. H., S. E. Jones, J. T. Lennon, and A. C. Martiny. 2015. “Microbiomes in Light of Traits: A Phylogenetic Perspective.” Science 350, no. 6261: aac9323.
Massalha, H., E. Korenblum, S. Malitsky, O. H. Shapiro, and A. Aharoni. 2017. “Live Imaging of Root–Bacteria Interactions in a Microfluidics Setup.” Proceedings of the National Academy of Sciences 114, no. 17: 4549–4554.
Mataigne, A., N. Vannier, P. Vandenkoornhuyse, and S. Hacquard. 2022. “Multigenome Metabolic Modeling Predicts Functional Interdependencies in the Arabidopsis Root Microbiome.” Microbiome 10, no. 1: 217.
Mavrodi, O. V., J. R. McWilliams, J. O. Peter, et al. 2021. “Root Exudates Alter the Expression of Diverse Metabolic, Transport, Regulatory, and Stress Response Genes in Rhizosphere Pseudomonas.” Frontiers in Microbiology 12: 651282.
Mazumder, M., H. Tikariha, S. Mayalagu, et al. 2026. “An Ecology‐Driven Microbial Consortium Enhances Plant Growth and Immunity While Sustaining Rhizospheric Microbial Balance.” Plant Communications 7, no. 3: 101665.
Mažylytė, R., J. Kailiuvienė, E. Mažonienė, et al. 2024. “The Coinoculation Effect on Triticum aestivum Growth With Synthetic Microbial Communities (SynComs) and Their Potential in Agrobiotechnology.” Plants 13, no. 12: 1716.
McCarty, N. S., and R. Ledesma‐Amaro. 2019. “Synthetic Biology Tools to Engineer Microbial Communities for Biotechnology.” Trends in Biotechnology 37, no. 2: 181–197.
McNaughton, A. D., E. L. Bredeweg, J. Manzer, et al. 2021. “Bayesian Inference for Integrating Yarrowia lipolytica Multiomics Datasets With Metabolic Modeling.” ACS Synthetic Biology 10, no. 11: 2968–2981.
Md Mukhtar, H., I. Saimon, A. Md. Imran, and R. Mehdi. 2025. “Assessing the Potential and Limitations of Organic Farming for Sustainable Agriculture in Bangladesh.” Environmental Challenges 21: 101346.
Meroz, N., N. Tovi, Y. Sorokin, and J. Friedman. 2021. “Community Composition of Microbial Microcosms Follows Simple Assembly Rules at Evolutionary Timescales.” Nature Communications 12, no. 1: 2891.
Miccio, L., V. Marchesano, M. Mugnano, S. Grilli, and P. Ferraro. 2016. “Light Induced DEP for Immobilizing and Orienting Escherichia coli Bacteria.” Optics and Lasers in Engineering 76: 34–39.
Miller, K., A. L. Eggenberger, K. Lee, et al. 2021. “An Improved Biolistic Delivery and Analysis Method for Evaluation of DNA and CRISPR–Cas Delivery Efficacy in Plant Tissue.” Scientific Reports 11, no. 1: 7695.
Miller, E. T., and C. A. Klausmeier. 2017. “Evolutionary Stability of Coexistence Due to the Storage Effect in a Two‐Season Model.” Theoretical Ecology 10, no. 1: 91–103.
Molefe, R. R., A. E. Amoo, and O. O. Babalola. 2023. “Communication Between Plant Roots and the Soil Microbiome; Involvement in Plant Growth and Development.” Symbiosis 90, no. 3: 231–239.
Molina‐Romero, D., S. Juárez‐Sánchez, B. Venegas, et al. 2021. “A Bacterial Consortium Interacts With Different Varieties of Maize, Promotes the Plant Growth, and Reduces the Application of Chemical Fertilizer Under Field Conditions.” Frontiers in Sustainable Food Systems 4: 616757.
Momeni, B., L. Xie, and W. Shou. 2017. “Lotka‐Volterra Pairwise Modeling Fails to Capture Diverse Pairwise Microbial Interactions.” eLife 6: e25051.
Monohon, S. J., D. K. Manter, and J. M. Vivanco. 2021. “Conditioned Soils Reveal Plant‐Selected Microbial Communities That Impact Plant Drought Response.” Scientific Reports 11, no. 1: 21153.
Montoya, M., D. Durán‐Wendt, D. Garrido‐Sanz, et al. 2025. “Functional Characterization of a Synthetic Bacterial Community (SynCom) and Its Impact on Gene Expression and Growth Promotion in Tomato.” Agronomy 15, no. 8: 1794.
Mulaudzi, M. S., L. P. Nephali, and F. Tugizimana. 2025. “AI‐Integrated Metabolomics Maps Functional Divergence of Microbial Consortia in Field‐Grown Maize.” Plant Cell Reports 44, no. 10: 211.
Nezhad, A. S. 2014. “Microfluidic Platforms for Plant Cells Studies.” Lab on a Chip 14, no. 17: 3262–3274.
Niehaus, L., I. Boland, M. Liu, et al. 2019. “Microbial Coexistence Through Chemical‐Mediated Interactions.” Nature Communications 10, no. 1: 2052.
Novak, V., P. F. Andeer, B. P. Bowen, et al. 2024. “Reproducible Growth of Brachypodium in EcoFAB 2.0 Reveals That Nitrogen Form and Starvation Modulate Root Exudation.” Science Advances 10, no. 1: eadg7888.
Oliveira, E. M., R. Wittwer, M. Hartmann, T. Keller, N. Buchmann, and M. G. A. van der Heijden. 2024. “Effects of Conventional, Organic and Conservation Agriculture on Soil Physical Properties, Root Growth and Microbial Habitats in a Long‐Term Field Experiment.” Geoderma 447: 116927.
Orozco‐Mosqueda, M. C., J. Duan, M. DiBernardo, et al. 2019. “The Production of ACC Deaminase and Trehalose by the Plant Growth Promoting Bacterium Pseudomonas sp. UW4 Synergistically Protect Tomato Plants Against Salt Stress.” Frontiers in Microbiology 10: 1392–13102.
Oteino, N., R. D. Lally, S. Kiwanuka, et al. 2015. “Plant Growth Promotion Induced by Phosphate Solubilizing Endophytic Pseudomonas Isolates.” Frontiers in Microbiology 6: 745.
Palmer, A. G., A. C. Senechal, A. Mukherjee, J.‐M. Ané, and H. E. Blackwell. 2014. “Plant Responses to Bacterial n‐Acyl L‐Homoserine Lactones Are Dependent on Enzymatic Degradation to L‐Homoserine.” ACS Chemical Biology 9, no. 8: 1834–1845.
Pande, S., H. Merker, K. Bohl, et al. 2014. “Fitness and Stability of Obligate Cross‐Feeding Interactions That Emerge Upon Gene Loss in Bacteria.” ISME Journal 8, no. 5: 953–962.
Pandin, C., D. Le Coq, A. Canette, S. Aymerich, and R. Briandet. 2017. “Should the Biofilm Mode of Life Be Taken Into Consideration for Microbial Biocontrol Agents?.” Microbial Biotechnology 10, no. 4: 719–734.
Pankievicz, V. C. S., P.‐M. Delaux, V. Infante, et al. 2022. “Nitrogen Fixation and Mucilage Production on Maize Aerial Roots Is Controlled by Aerial Root Development and Border Cell Functions.” Frontiers in Plant Science 13: 977056.
Park, S. Y., D. Yang, S. H. Ha, and S. Y. Lee. 2018. “Metabolic Engineering of Microorganisms for the Production of Natural Compounds.” Advanced Biosystems 2, no. 1: 1700190.
Parker, M. T., and A. M. Kunjapur. 2020. “Deployment of Engineered Microbes: Contributions to the Bioeconomy and Considerations for Biosecurity.” Health Security 18, no. 4: 278–296.
Ploll, U., M. Arato, J. Börner, and M. Hartmann. 2022. “Sustainable Innovations: A Qualitative Study on Farmers' Perceptions Driving the Diffusion of Beneficial Soil Microbes in Germany and the UK.” Sustainability 14, no. 10: 5749.
Portal‐Gonzalez, N., W. Wang, W. He, and R. Santos‐Bermudez. 2025. “Engineering Plant Holobionts for Climate‐Resilient Agriculture.” ISME Journal 19, no. 1: wraf158.
Prajapati, C. S., N. K. Priya, S. Bishnoi, et al. 2025. “The Role of Participatory Approaches in Modern Agricultural Extension: Bridging Knowledge Gaps for Sustainable Farming Practices.” Journal of Experimental Agriculture International 47, no. 2: 204–222.
Priyanka, S. Srivastava, and S. Sharma. 2022. “Metabolomic Insight Into the Synergistic Mechanism of Action of a Bacterial Consortium in Plant Growth Promotion.” Journal of Bioscience and Bioengineering 134, no. 5: 399–406.
Proctor, L. M., J. Dore, E. Maguin, K. Wannerberger, and C. Vincent. 2025. “A Global Partnership to Advance the Microbiome in Human, Plant, Animal, and Planetary Health.” Lancet Microbe 6, no. 8: 101120.
Ragland, C. J., K. Y. Shih, and J. R. Dinneny. 2024. “Choreographing Root Architecture and Rhizosphere Interactions Through Synthetic Biology.” Nature Communications 15, no. 1: 1370.
Recorbet, G., C. Steinberg, and G. Faurie. 1992. “Survival in Soil of Genetically Engineered Escherichia coli as Related to Inoculum Density, Predation and Competition.” FEMS Microbiology Ecology 101, no. 4: 251–260.
Rodriguez, J., M. Cordaillat‐Simmons, B. Pot, and C. Druart. 2025. “The Regulatory Framework for Microbiome‐Based Therapies: Insights Into European Regulatory Developments.” npj Biofilms and Microbiomes 11, no. 1: 53.
Rodríguez‐Salazar, J., R. Suã¡rez, J. Caballero‐Mellado, and G. Iturriaga. 2009. “Trehalose Accumulation in Azospirillum brasilense Improves Drought Tolerance and Biomass in Maize Plants.” FEMS Microbiology Letters 296, no. 1: 52–59.
Rostamian, A., P. Moaveni, S. MehdiSadeghi, H. Mozafari, and F. Rajabzadeh. 2023. “Effective Drought Mitigation by Rhizobacteria Consortium in Wheat Field Trials.” Rhizosphere 25: 100653.
Rotaru, A.‐E., P. M. Shrestha, F. Liu, et al. 2014. “Direct Interspecies Electron Transfer Between Geobacter metallireducens and Methanosarcina barkeri.” Applied and Environmental Microbiology 80, no. 15: 4599–4605.
Rotoni, C., M. F. A. Leite, L. C. Wong, et al. 2024. “Cultivar Governs Plant Response to Inoculation With Single Isolates and the Microbiome Associated With Arbuscular Mycorrhizal Fungi.” Applied Soil Ecology 197: 105347.
Rubin, B. E., S. Diamond, B. F. Cress, et al. 2022. “Species‐ and Site‐Specific Genome Editing in Complex Bacterial Communities.” Nature Microbiology 7, no. 1: 34–47.
Ruffolo, J. A., S. Nayfach, J. Gallagher, et al. 2025. “Design of Highly Functional Genome Editors by Modelling CRISPR–Cas Sequences.” Nature 645, no. 8080: 518–525.
Rupal, B. S., E. A. Garcia, C. Ayranci, and A. J. Qureshi. 2019. “3D Printed 3d‐Microfluidics: Recent Developments and Design Challenges.” Journal of Integrated Design and Process Science 22, no. 1: 5–20.
Ryu, M.‐H., J. Zhang, T. Toth, et al. 2020. “Control of Nitrogen Fixation in Bacteria That Associate With Cereals.” Nature Microbiology 5, no. 2: 314–330.
Salvatori, N., A. Giorgio, O. Muller, U. Rascher, and A. Peressotti. 2021. “A Low‐Cost Automated Growth Chamber System for Continuous Measurements of Gas Exchange at Canopy Scale in Dynamic Conditions.” Plant Methods 17, no. 1: 69.
Schenk, P. M., M. Batool, H. Mirzaee, and A. Abbott. 2024. “Customized Plant Growth Promotion With Soil‐ and Cultivar‐Compatible Microbial Biofertilizers.” Agronomy 14, no. 9: 1915.
Schmitz, L., Z. Yan, M. Schneijderberg, et al. 2022. “Synthetic Bacterial Community Derived From a Desert Rhizosphere Confers Salt Stress Resilience to Tomato in the Presence of a Soil Microbiome.” ISME Journal 16, no. 8: 1907–1920.
Schnabel, T., and E. Sattely. 2021a. “Engineering Posttranslational Regulation of Glutamine Synthetase for Controllable Ammonia Production in the Plant Symbiont Azospirillum brasilense.” Applied and Environmental Microbiology 87, no. 14: e00582‐00521.
Schnabel, T., and E. Sattely. 2021b. “Improved Stability of Engineered Ammonia Production in the Plant‐Symbiont Azospirillum brasilense.” ACS Synthetic Biology 10, no. 11: 2982–2996.
Sedlmayer, F., D. Hell, M. Müller, D. Ausländer, and M. Fussenegger. 2018. “Designer Cells Programming Quorum‐Sensing Interference With Microbes.” Nature Communications 9, no. 1: 1822.
Serrano, K., M. Bezrutczyk, D. Goudeau, et al. 2024. “Spatial Cotranscriptomics Reveals Discrete Stages of the Arbuscular Mycorrhizal Symbiosis.” Nature Plants 10, no. 4: 673–688.
Sharma, A., and P. Bora. 2025. “Engineering Synthetic Microbial Communities to Restructure the Phytobiome for Plant Health and Productivity.” World Journal of Microbiology and Biotechnology 41, no. 7: 228.
Shayanthan, A., P. A. C. Ordoñez, and I. J. Oresnik. 2022. “The Role of Synthetic Microbial Communities (SynCom) in Sustainable Agriculture.” Frontiers in Agronomy 4: 896307.
Shekhawat, K., K. Fröhlich, G. X. García‐Ramírez, M. A. Trapp, and H. Hirt. 2022. “Ethylene: A Master Regulator of Plant–Microbe Interactions Under Abiotic Stresses.” Cells 12, no. 1: 31.
Shipar, S. I. 2025. Exploring the Role of Bacterial Synthetic Communities (SynComs) in Alfalfa Plant Resilience Under Drought Stress. University of Zagreb.
Shittu, O. E., B. J. Enagbonma, and O. O. Babalola. 2025. “Deciphering the Influence of Fertilization Systems on the Allium ampeloprasum Rhizosphere Microbial Diversity and Community Structure Through a Shotgun Metagenomics Profiling Approach.” Environmental Microbiome 20, no. 1: 126.
Shukla, V., and M. Barberon. 2021. “Building and Breaking of a Barrier: Suberin Plasticity and Function in the Endodermis.” Current Opinion in Plant Biology 64: 102153.
Shulse, C. N., M. Chovatia, C. Agosto, et al. 2019. “Engineered Root Bacteria Release Plant‐Available Phosphate From Phytate.” Applied and Environmental Microbiology 85, no. 18: e01210–e01219.
Silva‐Andrade, C., S. Hernández, P. Saa, E. Perez‐Rueda, D. Garrido, and A. J. Martin. 2025. “A Machine‐Learning Approach for Predicting Butyrate Production by Microbial Consortia Using Metabolic Network Information.” PeerJ 13: e19296.
Singh, N. K., K. Sachan, G. Ranjitha G., et al. 2024. “Building Soil Health and Fertility Through Organic Amendments and Practices: A Review.” Asian Journal of Soil Science and Plant Nutrition 10, no. 1: 175–197.
Singla, P. 2021. “Plant Synthetic Biology: A Paradigm Shift Targeting Stress Mitigation, Reduction of Ecological Footprints and Sustainable Transformation in Agriculture.” In Plant Stress Biology: Strategies and Trends, 435–489. Springer.
Smanski, M. J., S. Bhatia, D. Zhao, et al. 2014. “Functional Optimization of Gene Clusters by Combinatorial Design and Assembly.” Nature Biotechnology 32, no. 12: 1241–1249.
Smith, N. W., P. R. Shorten, E. Altermann, N. C. Roy, and W. C. McNabb. 2019. “The Classification and Evolution of Bacterial Cross‐Feeding.” Frontiers in Ecology and Evolution 7: 153.
Somaly, S., H. Meta, I. Sokra, and R. Lika. 2026. “Synthetic Biology Platforms for Sustainable Bioproduction: Advances, Challenges, and Industrial Prospects.” Journal of Agriculture and Technology 2, no. 1: 167–182.
Song, Y., Q. Chen, S. Luo, et al. 2026. “Ecology‐Guided Bacillus SynCom From a Rice–Duckweed Core Reveals Division of Labor for Concurrent Growth Promotion and Sheath Blight Suppression.” Microbiome 14, no. 1: 80.
Song, M., X. Zhang, J. Yang, et al. 2022. “Arabidopsis Plants Engineered for High Root Sugar Secretion Enhance the Diversity of Soil Microorganisms.” Biotechnology Journal 17, no. 11: 2100638.
Staehelin, C., J. Granado, J. Müller, et al. 1994. “Perception of Rhizobium Nodulation Factors by Tomato Cells and Inactivation by Root Chitinases.” Proceedings of the National Academy of Sciences 91, no. 6: 2196–2200.
Steinberg, M. S. 2007. “Differential Adhesion in Morphogenesis: A Modern View.” Current Opinion in Genetics & Development 17, no. 4: 281–286.
Stringlis, I. A., R. De Jonge, and M. J. Pieterse. 2019. “The Age of Coumarins in Plant–Microbe Interactions.” Plant and Cell Physiology 60, no. 7: 1405–1419.
Tabassum, N., H. I. Ahmed, S. Parween, et al. 2024. “Host Genotype, Soil Composition, and Geo‐Climatic Factors Shape the Fonio Seed Microbiome.” Microbiome 12, no. 1: 11.
Tan, C., M. T. Kalhoro, Y. Faqir, J. Ma, M. D. Osei, and G. Khaliq. 2022. “Climate‐Resilient Microbial Biotechnology: A Perspective on Sustainable Agriculture.” Sustainability 14, no. 9: 5574.
Tariq, A., S. Guo, F. Farhat, and X. Shen. 2025. “Engineering Synthetic Microbial Communities: Diversity and Applications in Soil for Plant Resilience.” Agronomy 15, no. 3: 513.
Tas, H., L. Grozinger, R. Stoof, V. de Lorenzo, and Á. Goñi‐Moreno. 2021. “Contextual Dependencies Expand the Reusability of Genetic Inverters.” Nature Communications 12, no. 1: 355.
Te Molder, D., W. Poncheewin, P. J. Schaap, and J. J. Koehorst. 2021. “Machine Learning Approaches to Predict the Plant‐Associated Phenotype of Xanthomonas Strains.” BMC Genomics 22, no. 1: 848.
Tecon, R., S. Mitri, D. Ciccarese, D. Or, J. R. van der Meer, and D. R. Johnson. 2019. “Bridging the Holistic‐Reductionist Divide in Microbial Ecology.” mSystems 4, no. 1: 00265–00218.
Then, C., K. Kawall, and N. Valenzuela. 2020. “Spatiotemporal Controllability and Environmental Risk Assessment of Genetically Engineered Gene Drive Organisms From the Perspective of European Union Genetically Modified Organism Regulation.” Integrated Environmental Assessment and Management 16, no. 5: 555–568.
Thingujam, D., S. Gouli, S. P. Cooray, et al. 2025. “Climate‐Resilient Crops: Integrating AI, Multiomics, and Advanced Phenotyping to Address Global Agricultural and Societal Challenges.” Plants 14, no. 17: 2699.
Thoenen, L., M. Kreuzer, C. Pestalozzi, et al. 2024. “The Lactonase BxdA Mediates Metabolic Specialisation of Maize Root Bacteria to Benzoxazinoids.” Nature Communications 15, no. 1: 6535.
Thorpe, C., W. Luo, Q. Ji, et al. 2025. “Enhancing Biolistic Plant Transformation and Genome Editing With a Flow Guiding Barrel.” Nature Communications 16, no. 1: 5624.
Timofeeva, A. M., M. R. Galyamova, and S. E. Sedykh. 2023. “Plant Growth‐Promoting Bacteria of Soil: Designing of Consortia Beneficial for Crop Production.” Microorganisms 11, no. 12: 2864.
Triadó‐Margarit, X., J. A. Capitán, M. Menéndez‐Serra, et al. 2019. “A Randomized Trait Community Clustering Approach to Unveil Consistent Environmental Thresholds in Community Assembly.” ISME Journal 13, no. 11: 2681–2689.
Tripathi, S. K., S. Chakrobortty, A. Tyagi, et al. 2025. “The Role of Plant–Microbe Partnerships in Ecosystem Functionality.” In Climate Change and Soil Microorganisms for Environmental Sustainability, edited by M. Saraf, D. Goswami, D. K. Maheshwari, Vol. 28, 127–151. Springer Nature Singapore.
Ullah, F., S. Ali, M. Siraj, M. S. Akhtar, and W. Zaman. 2025. “Plant Microbiomes Alleviate Abiotic Stress‐Associated Damage in Crops and Enhance Climate‐Resilient Agriculture.” Plants 14, no. 12: 1890.
Vallespir Lowery, N., and T. Ursell. 2019. “Structured Environments Fundamentally Alter Dynamics and Stability of Ecological Communities.” Proceedings of the National Academy of Sciences 116, no. 2: 379–388.
Van der Ent, S., B. W. M. Verhagen, R. Van Doorn, et al. 2008. “MYB72 Is Required in Early Signaling Steps of Rhizobacteria‐Induced Systemic Resistance in Arabidopsis.” Plant Physiology 146, no. 3: 1293–1304.
Vegh, P., S. Donovan, S. Rosser, G. Stracquadanio, and R. Fragkoudis. 2024. “Biofoundry‐Scale DNA Assembly Validation Using Cost‐Effective High‐Throughput Long‐Read Sequencing.” ACS Synthetic Biology 13, no. 2: 683–686.
Veličković, D., T. Winkler, V. Balasubramanian, et al. 2024. “RhizoMAP: A Comprehensive, Nondestructive, and Sensitive Platform for Metabolic Imaging of the Rhizosphere.” Plant Methods 20, no. 1: 117.
Vesa, I., and C. Vlad. 2008. “Assisted Decisions in Farming Management Based on Methods of Operations Research‐Linear Multiobject Programming.” Agricultura ‐ Revistă de Scedilla˜tiintcedilla˜ă scedilla˜i Practică Agricolă 67–68, no. 3/4: 74–82.
Von Wintersdorff, C. J. H., J. Penders, J. M. Van Niekerk, et al. 2016. “Dissemination of Antimicrobial Resistance in Microbial Ecosystems Through Horizontal Gene Transfer.” Frontiers in Microbiology 7: 173.
Wagh, J., K. Chanchal, S. Sonal, B. Praveena, G. Archana, and G. N. Kumar. 2016. “Inoculation of Genetically Modified Endophytic Herbaspirillum seropedicae Z67 Endowed With Gluconic and 2‐Ketogluconic Acid Secretion, Confers Beneficial Effects on Rice (Oriza sativa) Plants.” Plant and Soil 409, no. 1: 51–64.
Wanapaisan, P., N. Laothamteep, F. Vejarano, et al. 2018. “Synergistic Degradation of Pyrene by Five Culturable Bacteria in a Mangrove Sediment‐Derived Bacterial Consortium.” Journal of Hazardous Materials 342: 561–570.
Wang, Y., H. Liu, Z. Shen, et al. 2022. “Richness and Antagonistic Effects Coaffect Plant Growth Promotion by Synthetic Microbial Consortia.” Applied Soil Ecology 170: 104300.
Wang, W., Y. Xia, P. Zhang, et al. 2025b. “Narrow‐Spectrum Resource‐Utilizing Bacteria Drive the Stability of Synthetic Communities Through Enhancing Metabolic Interactions.” Nature Communications 16, no. 1: 6088.
Wang, C., C. Zhang, Z. Xie, et al. 2025a. “Engineered Silicate‐Solubilizing Bacterial Community Alleviates Nutrient Stress in Field‐Grown Maize by Enhancing Silicon Uptake and Optimizing Rhizosphere Microecology.” Field Crops Research 326: 109827.
Wankhade, A., E. Wilkinson, D. W. Britt, and A. Kaundal. 2025. “A Review of Plant–Microbe Interactions in the Rhizosphere and the Role of Root Exudates in Microbiome Engineering.” Applied Sciences 15, no. 13: 7127.
Wilbert, S. A., J. L. M. Welch, and G. G. Borisy. 2020. “Spatial Ecology of the Human Tongue Dorsum Microbiome.” Cell Reports 30, no. 12: 4003–4015.e3.
Williamson, J., A. C. Matthews, and B. Raymond. 2023. “Competition and Coassociation, but Not Phosphorous Availability, Shape the Benefits of Phosphate‐Solubilizing Root Bacteria for Maize (Zea mays).” Access Microbiology 5, no. 12: 000543.
Wrighton, K. C., B. C. Thomas, I. Sharon, et al. 2012. “Fermentation, Hydrogen, and Sulfur Metabolism in Multiple Uncultivated Bacterial Phyla.” Science 337, no. 6102: 1661–1665.
Wu, S., J. Liu, C. Liu, A. Yang, and J. Qiao. 2020. “Quorum Sensing for Population‐Level Control of Bacteria and Potential Therapeutic Applications.” Cellular and Molecular Life Sciences 77, no. 7: 1319–1343.
Xie, B.‐B., M. Li, K. Anantharaman, and N. V. Ravin. 2021. The Uncultured Microorganisms: Novel Technologies and Applications, Vol 12. Frontiers Media SA.
Xiong, R., X. He, N. Gao, et al. 2024. “Soil pH Amendment Alters the Abundance, Diversity, and Composition of Microbial Communities in Two Contrasting Agricultural Soils.” Microbiology Spectrum 12, no. 8: e04165‐04123.
Xu, P. 2021. “Dynamics of Microbial Competition, Commensalism, and Cooperation and Its Implications for Coculture and Microbiome Engineering.” Biotechnology and Bioengineering 118, no. 1: 199–209.
Xu, X., C. Dinesen, A. Pioppi, Á. T. Kovács, and C. N. Lozano‐Andrade. 2025. “Composing a Microbial Symphony: Synthetic Communities for Promoting Plant Growth.” Trends in Microbiology 33, no. 7: 738–751.
Xu, J., X.‐L. Li, and L. Luo. 2012. “Effects of Engineered Sinorhizobium meliloti on Cytokinin Synthesis and Tolerance of Alfalfa to Extreme Drought Stress.” Applied and Environmental Microbiology 78, no. 22: 8056–8061.
Xu, C., and H. Yu. 2021. “Insights Into Constructing a Stable and Efficient Microbial Consortium.” Chinese Journal of Chemical Engineering 30: 112–120.
Yadav, A., M. Chen, S. M. Acharya, et al. 2025. “A Stable 15‐Member Bacterial SynCom Promotes Brachypodium Growth Under Drought Stress.” Frontiers in Microbiology 16: 1649750.
Yamazaki, S., M. Nakayasu, K. Kanai, et al. 2025. “From Model to Field: Predictive Design of Microbial Communities for Resilient Crop Performance.” Preprint, bioRxiv: 2025.2010. 2021.683643.
Yang, X., Q. Li, Y. Zhang, et al. 2026. “Construction of Drought‐Resistant Microbial Consortium and Effect on Alfalfa Growth Under Drought Stress.” Plants 15, no. 5: 744.
Ye, X., K. Qin, A. R. Fernie, and Y. Zhang. 2025. “Prospects for Synthetic Biology in 21st Century Agriculture.” Journal of Genetics and Genomics 52, no. 8: 967–986.
Yee, M. O., P. Kim, Y. Li, A. K. Singh, T. R. Northen, and R. Chakraborty. 2021. “Specialized Plant Growth Chamber Designs to Study Complex Rhizosphere Interactions.” Frontiers in Microbiology 12: 625752.
Yin, C., C. H. Hagerty, and T. C. Paulitz. 2022. “Synthetic Microbial Consortia Derived From Rhizosphere Soil Protect Wheat Against a Soilborne Fungal Pathogen.” Frontiers in Microbiology 13: 908981.
Youseif, S. H., F. H. Abd El‐Megeed, E. A. Humm, et al. 2021. “Comparative Analysis of the Cultured and Total Bacterial Community in the Wheat Rhizosphere Microbiome Using Culture‐Dependent and Culture‐Independent Approaches.” Microbiology Spectrum 9, no. 2: e0067821.
Yurgel, S. N., N. Ajeethan, and A. Smertenko. 2022. “Response of Plant‐Associated Microbiome to Plant Root Colonization by Exogenous Bacterial Endophyte in Perennial Crops.” Frontiers in Microbiology 13: 863946.
Yusuf, A., M. Li, S.‐Y. Zhang, et al. 2025. “Harnessing Plant–Microbe Interactions: Strategies for Enhancing Resilience and Nutrient Acquisition for Sustainable Agriculture.” Frontiers in Plant Science 16: 1503730.
Zafar‐ul‐Hye, M., S. Danish, M. Abbas, M. Ahmad, and T. M. Munir. 2019. “ACCDeaminase Producing PGPR Bacillus amyloliquefaciens and Agrobacterium fabrum Along With Biochar Improve Wheat Productivity Under Drought Stress.” Agronomy 9, no. 7: 343.
Zhalnina, K., K. B. Louie, Z. Hao, et al. 2018. “Dynamic Root Exudate Chemistry and Microbial Substrate Preferences Drive Patterns in Rhizosphere Microbial Community Assembly.” Nature Microbiology 3, no. 4: 470–480.
Zhan, C. 2024. “Long‐Term Ecological Impacts of Engineered Synthetic Microbial Communities (SynComs) in Agricultural Systems.” International Journal of Molecular Ecology and Conservation 14, no. 4: 144–154.
Zhang, Z., T. E. P. Kimkes, and M. Heinemann. 2019. “Manipulating Rod‐Shaped Bacteria With Optical Tweezers.” Scientific Reports 9, no. 1: 19086.
Zhao, G., T. Yang, Z. Chen, and W. Zhang. 2025. “Phosphorus‐Dependent Shifts in Acquisition Strategies Revealed by Integrated Transcriptomics and Metabolomics in Soybean Roots.” BMC Plant Biology 25, no. 1: 1753.
Zhao, C., A. Yaschenko, J. M. Alonso, and A. N. Stepanova. 2021. “Leveraging Synthetic Biology Approaches in Plant Hormone Research.” Current Opinion in Plant Biology 60: 101998.
Zhong, V., B. N. Archibald, and J. A. N. Brophy. 2023. “Transcriptional and Posttranscriptional Controls for Tuning Gene Expression in Plants.” Current Opinion in Plant Biology 71: 102315.
Ziemba, C., Y. Shabtai, M. Piatkovsky, and M. Herzberg. 2016. “Cellulose Effects on Morphology and Elasticity of Vibrio fischeri Biofilms.” npj Biofilms and Microbiomes 2, no. 1: 1.
Zuroff, T. R., and W. R. Curtis. 2012. “Developing Symbiotic Consortia for Lignocellulosic Biofuel Production.” Applied Microbiology and Biotechnology 93, no. 4: 1423–1435.
Contributed Indexing: Keywords: compliance; ecosafety; host–microbe compatibility; microbial consortia; multiomics
Entry Date(s): Date Created: 20260712 Latest Revision: 20260712
Update Code: 20260713
DOI: 10.1002/bit.70291
PMID: 42437522
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1097-0290
DOI:10.1002/bit.70291