Trends in Alcohol-Related Deaths in the United States Over 55 Years: 1968-2023.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος:	Trends in Alcohol-Related Deaths in the United States Over 55 Years: 1968-2023.
Συγγραφείς:	Zulfiqar M; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan., Uddin MS; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan., Abbas F; Department of Medicine, Fatima Memorial Hospital, Lahore, Pakistan., Sajjad A; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan., Uddin A; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan., Shah SAA; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan., Fonarow GC; Ahmanson-UCLA Cardiomyopathy Center, Ronald Reagan-UCLA Medical Center, Los Angeles, California, USA., Waqas SA; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan., Yokolo H; Department of Research, Medical Research Circle (MedReC), Goma, Democratic Republic of the Congo., Qureshi S; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Πηγή:	Alcohol, clinical & experimental research [Alcohol Clin Exp Res (Hoboken)] 2026 Jul; Vol. 50 (7), pp. e70321.
Τύπος έκδοσης:	Journal Article
Γλώσσα:	English
Στοιχεία περιοδικού:	Publisher: Wiley Periodicals Country of Publication: United States NLM ID: 9918609780906676 Publication Model: Print Cited Medium: Internet ISSN: 2993-7175 (Electronic) Linking ISSN: 29937175 NLM ISO Abbreviation: Alcohol Clin Exp Res (Hoboken) Subsets: MEDLINE
Imprint Name(s):	Original Publication: Hoboken, NJ : Wiley Periodicals, [2023]-
Ιατρικοί όροι (MeSH):	Alcohol Drinking/mortality , Alcohol Drinking/trends , Alcohol-Related Disorders*/mortality, United States/epidemiology ; Mortality/trends ; Humans ; Male ; Female ; Middle Aged ; Aged ; Adult
Περίληψη:	Background: Alcohol consumption is a leading cause of preventable mortality worldwide. We examined long-term trends in alcohol-related deaths in the United States over 55 years (1968-2023) and analyzed demographic disparities. Methods: Using CDC WONDER data, we identified alcohol-related deaths among adults aged ≥ 25 years. Age-adjusted mortality rates (AAMRs) per 100,000 population were calculated, and joinpoint regression analyzed temporal trends by sex, race, age, and geographic region. Results: From 1968 to 2023, 1,321,804 alcohol-related deaths occurred. AAMRs increased from 13.1 to 19.3 (AAPC: 0.7, p < 0.001), with a sharp acceleration during 2018-2021 (APC: 14.1) followed by a decline during 2021-2023 (APC: -6.9). Males consistently had higher mortality than females, though the gender gap narrowed. A striking racial inversion occurred: mortality among Black individuals declined from 27.7 to 13.5 (AAPC: -1.4), while mortality among White individuals increased from 11.3 to 21.1 (AAPC: 1.1) with older adults (65+) showing the steepest long-term increase (AAPC: 1.4). Regionally, the Midwest experienced the greatest rise in mortality (AAPC: 1.4), while the Northeast remained stable. Conclusions: Alcohol-related mortality has increased substantially over 55 years, with profound demographic shifts including a complete racial disparity inversion and narrowing gender gap. Recent declines (2021-2023) offer cautious optimism, but sustained, targeted interventions are needed for high-risk populations. (© 2026 Research Society on Alcohol.)
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Contributed Indexing:	Keywords: CDC WONDER; age‐adjusted mortality rate; alcohol; gender disparities; health disparities; mortality trends; racial disparities
Entry Date(s):	Date Created: 20260710 Date Completed: 20260710 Latest Revision: 20260726
Update Code:	20260726
PubMed Central ID:	PMC13353243
DOI:	10.1111/acer.70321
PMID:	42429647
Βάση Δεδομένων:	MEDLINE

Περιγραφή
ISSN:	2993-7175
DOI:	10.1111/acer.70321