Academic Journal
Safety Assessment of Radish Root - Derived Ingredients as Used in Cosmetics.
| Title: | Safety Assessment of Radish Root - Derived Ingredients as Used in Cosmetics. |
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| Authors: | Raj PS; Cosmetic Ingredient Review Former Senior Scientific Analyst/Writer., Bergfeld WF; Expert Panel for Cosmetic Ingredient Safety Member., Belsito DV; Expert Panel for Cosmetic Ingredient Safety Member., Cohen DE; Expert Panel for Cosmetic Ingredient Safety Former Member., Klaassen CD; Expert Panel for Cosmetic Ingredient Safety Member., Liebler DC; Expert Panel for Cosmetic Ingredient Safety Former Member., Peterson LA; Expert Panel for Cosmetic Ingredient Safety Former Member., Rettie AE; Expert Panel for Cosmetic Ingredient Safety Member., Ross D; Expert Panel for Cosmetic Ingredient Safety Member., Shank RC; Expert Panel for Cosmetic Ingredient Safety Former Member., Slaga TJ; Expert Panel for Cosmetic Ingredient Safety Former Member., Snyder PW; Expert Panel for Cosmetic Ingredient Safety Member., Tilton SC; Expert Panel for Cosmetic Ingredient Safety Member., Fiume MM; Cosmetic Ingredient Review Senior Director., Heldreth B; Cosmetic Ingredient Review Executive Director. |
| Source: | International journal of toxicology [Int J Toxicol] 2026 Jul-Aug; Vol. 45 (2_suppl), pp. 112S-123S. Date of Electronic Publication: 2026 Jul 01. |
| Publication Type: | Journal Article; Review |
| Language: | English |
| Journal Info: | Publisher: Sage Publications Country of Publication: United States NLM ID: 9708436 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1092-874X (Electronic) Linking ISSN: 10915818 NLM ISO Abbreviation: Int J Toxicol Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2009- : Thousand Oaks, CA : Sage Publications Original Publication: Washington, DC : Taylor & Francis, c1997- |
| MeSH Terms: | Raphanus*/chemistry , Cosmetics*/chemistry , Cosmetics*/toxicity , Plant Roots*/chemistry , Plant Extracts*/toxicity , Consumer Product Safety*, Animals ; Humans |
| Abstract: | The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 7 radish root-derived ingredients, most of which are reported to function as hair and skin conditioning agents in cosmetic products. Because final product formulations may contain multiple botanicals, each containing similar constituents of concern, formulators are advised to be aware of these constituents and to avoid reaching levels that may be hazardous to consumers. With radish root-derived ingredients, the Panel was concerned about the presence of anthocyanins and isothiocyanates in cosmetics. Industry should use current good manufacturing practices to minimize impurities that could be present in botanical ingredients. The Panel reviewed the available data and concluded that these ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-sensitizing. |
| Competing Interests: | Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. |
| Contributed Indexing: | Keywords: Cosmetic Ingredient Review; Cosmetics; Expert Panel for Cosmetic Ingredient Safety; Lactobacillus/Radish Root Ferment Extract Filtrate; Lactobacillus/Radish Root Ferment Filtrate; Leuconostoc/Radish Root Ferment Filtrate; Leuconostoc/Radish Root Ferment Lysate Filtrate; Raphanus Sativus (Radish) Root Extract; Raphanus Sativus (Radish) Root Juice; Raphanus Sativus (Radish) Root Powder; Safety |
| Substance Nomenclature: | 0 (Cosmetics) 0 (Plant Extracts) |
| Entry Date(s): | Date Created: 20260701 Date Completed: 20260726 Latest Revision: 20260803 |
| Update Code: | 20260803 |
| DOI: | 10.1177/10915818261455269 |
| PMID: | 42381443 |
| Database: | MEDLINE |
| ISSN: | 1092-874X |
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| DOI: | 10.1177/10915818261455269 |