Academic Journal

Refusal of Hospital-Based Oral Cancer Treatment Driven by Health Beliefs in Pakistan: A Qualitative Study.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Refusal of Hospital-Based Oral Cancer Treatment Driven by Health Beliefs in Pakistan: A Qualitative Study.
Συγγραφείς: Amanat MU; Department of Oral Diagnostic Sciences, Faculty of Dentistry, Prince of Songkla University, Hat Yai, Songkhla, Thailand., Sriplung H; Department of Epidemiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand., Wichaidit W; Department of Epidemiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand., Naorungroj S; Department of Conservative Dentistry and Research Center of Excellence for Oral Health, Faculty of Dentistry, Prince of Songkla University, Hat Yai, Songkhla, Thailand. Electronic address: supawadee.n@psu.ac.th., Kerdpon D; Department of Oral Diagnostic Sciences, Faculty of Dentistry, Prince of Songkla University, Hat Yai, Songkhla, Thailand. Electronic address: duangporn.ke@gmail.com.
Πηγή: International dental journal [Int Dent J] 2026 Oct; Vol. 76 (5), pp. 109701. Date of Electronic Publication: 2026 Jun 27.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: England NLM ID: 0374714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-595X (Electronic) Linking ISSN: 00206539 NLM ISO Abbreviation: Int Dent J Subsets: MEDLINE
Imprint Name(s): Publication: 2021- : London : Elsevier
Original Publication: London : FDI World Dental
Ιατρικοί όροι (MeSH): Treatment Refusal*/psychology , Mouth Neoplasms*/therapy , Mouth Neoplasms*/psychology , Health Knowledge, Attitudes, Practice* , Attitude to Health*, Humans ; Pakistan ; Female ; Qualitative Research ; Male ; Middle Aged ; Adult ; Interviews as Topic ; Decision Making
Περίληψη: Objectives: Hospital-based treatment refusal among oral cancer (OC) patients remains poorly understood. No qualitative studies have examined this phenomenon specifically in OC. This study aimed to explore the beliefs and attitudes underlying treatment refusal among OC patients in Pakistan.
Methods: We conducted a theory-informed qualitative case study guided by the Health Belief Model (HBM) using purposive criterion sampling. Semistructured interviews were conducted with eight OC patients who refused hospital-based treatment, eight family members involved in decision-making, and three oral surgeons. Interviews were audio-recorded, transcribed verbatim, translated into English, and analysed using inductive thematic analysis. Emergent themes were subsequently interpreted in relation to HBM constructs using abductive, theory-informed pattern matching. Methodological rigour was enhanced through data source triangulation and member checking.
Results: From the 19 in-depth interviews, we identified seven interconnected themes underlying treatment refusal: perceived susceptibility, perceived severity, perceived benefits, perceived barriers, self-efficacy, cues to action, and religious beliefs. Treatment refusal was shaped by fatalistic perceptions of cancer incurability, intense fears of treatment-related harm, and substantial financial, access, and role-related constraints. Strong family influence and trust in traditional and complementary medicine further reinforced these decisions. Religious interpretations functioned bidirectionally, reinforcing acceptance of divine destiny and legitimizing nonbiomedical healing pathways, while in some cases also supporting treatment-seeking through religious doctrine.
Conclusion: Refusal of hospital-based OC treatment reflects a culturally embedded decision-making process shaped by interacting sociocultural, religious, and structural factors. The findings support the applicability of the HBM in this context and inform the development of culturally responsive, communication-focused interventions in oral oncology.
Clinical Relevance: Recognition of belief-driven treatment refusal can help clinicians tailor communication, address fears of treatment harm, and engage family and religious influences to improve acceptance of hospital-based OC care.
(Copyright © 2026 The Authors. Published by Elsevier Inc. All rights reserved.)
Competing Interests: Conflict of interest The authors have no conflicts of interest relevant to this article.
References: J Eval Clin Pract. 2011 Apr;17(2):268-74. (PMID: 20874835)
Public Health. 2014 Mar;128(3):268-73. (PMID: 24529635)
J Dent Sci. 2026 Apr 01;21(2):838-844. (PMID: 42688971)
J Altern Complement Med. 2009 May;15(5):545-50. (PMID: 19422284)
Health Educ Behav. 2018 Jun;45(3):435-443. (PMID: 29025281)
Int J Qual Health Care. 2007 Dec;19(6):349-57. (PMID: 17872937)
Can Oncol Nurs J. 2022 Apr 1;32(2):198-205. (PMID: 35582248)
Oral Oncol. 2021 Jan;112:105044. (PMID: 33130545)
Curr Oncol. 2023 Aug 22;30(9):7789-7801. (PMID: 37754480)
Int J Hypertens. 2018 Jun 19;2018:4701097. (PMID: 30018819)
Int Dent J. 2025 Dec;75(6):103946. (PMID: 41075462)
Biomed Res Int. 2020 Apr 21;2020:1850541. (PMID: 32382530)
Health Psychol Rev. 2014;8(3):253-69. (PMID: 25053213)
Clin Otolaryngol. 2018 Feb;43(1):164-171. (PMID: 28627802)
Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Sep;132(3):312-319. (PMID: 34284963)
Psychooncology. 2021 Apr;30(4):511-519. (PMID: 33205560)
Acta Otorhinolaryngol Ital. 2021 Feb;41(1):18-23. (PMID: 33746218)
Head Neck. 2020 Jan;42(1):33-42. (PMID: 31584746)
Int J Radiat Oncol Biol Phys. 2014 Jul 15;89(4):756-64. (PMID: 24803037)
Laryngoscope. 2018 Mar;128(3):664-669. (PMID: 28865100)
J Formos Med Assoc. 2020 Jan;119(1 Pt 3):392-398. (PMID: 31280909)
J Dent Sci. 2026 Jan;21(1):78-87. (PMID: 41585165)
Qual Health Res. 2016 Nov;26(13):1753-1760. (PMID: 26613970)
J Pastoral Care Counsel. 2018 Sep;72(3):180-189. (PMID: 30231824)
BMC Palliat Care. 2023 Feb 7;22(1):10. (PMID: 36750817)
Contributed Indexing: Keywords: Case study; Health Belief Model; Oral cancer; Pakistan; Treatment refusal
Entry Date(s): Date Created: 20260628 Date Completed: 20260916 Latest Revision: 20260926
Update Code: 20260926
PubMed Central ID: PMC13329492
DOI: 10.1016/j.identj.2026.109701
PMID: 42365791
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1875-595X
DOI:10.1016/j.identj.2026.109701