Academic Journal

A meta-analysis of cognitive behavioral therapy for substance use disorder: Treatment effects by comparator type and consumption and psychosocial outcomes.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: A meta-analysis of cognitive behavioral therapy for substance use disorder: Treatment effects by comparator type and consumption and psychosocial outcomes.
Συγγραφείς: Magill M; Brown University, Center for Alcohol and Addiction Studies, Providence, RI, USA. Electronic address: molly_magill@brown.edu., Nichols LM; Brown University, Center for Alcohol and Addiction Studies, Providence, RI, USA., Kiluk BD; Yale School of Medicine, New Haven, CT, USA., Alton E; Brown University, Center for Alcohol and Addiction Studies, Providence, RI, USA., Tartak O; Brown University, Center for Alcohol and Addiction Studies, Providence, RI, USA., Ray LA; University of California at Los Angeles, Los Angeles, CA, USA.
Πηγή: Behaviour research and therapy [Behav Res Ther] 2026 Aug; Vol. 203, pp. 105101. Date of Electronic Publication: 2026 Jun 24.
Τύπος έκδοσης: Journal Article; Meta-Analysis; Systematic Review
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Elsevier Science Country of Publication: England NLM ID: 0372477 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-622X (Electronic) Linking ISSN: 00057967 NLM ISO Abbreviation: Behav Res Ther Subsets: MEDLINE
Imprint Name(s): Publication: Oxford : Elsevier Science
Original Publication: Oxford [etc.]
Ιατρικοί όροι (MeSH): Cognitive Behavioral Therapy*/methods , Substance-Related Disorders*/therapy , Substance-Related Disorders*/psychology, Humans ; Treatment Outcome ; Randomized Controlled Trials as Topic ; Quality of Life
Περίληψη: Objective: This meta-analysis examines cognitive-behavioral therapy (CBT) for substance use disorders (SUD).
Method: A comprehensive literature search was conducted through June of 2025. All available outcomes were extracted and grouped into thirteen categories (e.g., abstinence, quantity of use, cognitive changes, quality of life), and into two broader outcome classes (i.e., consumption; psychosocial). Robust variance estimation accounted for clustering of effect sizes at the study level.
Results: The sample included 52 randomized clinical trials (54 study sites; k = 68 publications; 887 effect sizes; N = 9442 participants). CBT was efficacious based on overall between-group pooled estimates, but sub-group analyses suggested effect variability by comparator type. Specifically, CBT did not outperform other evidence-based treatments but did outperform usual care or minimal treatment for consumption outcomes (g = 0.14: 95% CI = 0.01, 0.26, I2 = 61.8%; k = 28, keffectsize(es) = 182). When CBT was tested as an addition to usual care, it showed significant effects for consumption outcomes (g = 0.44: 95% CI = 0.01, 0.88, p = .048; I2 = 87.6%; k = 16, kes = 55) and psychosocial functioning (g = 0.56: 95% CI = 0.08, 1.03, I2 = 93.8%; k = 14, kes = 69). Within condition (i.e., change from baseline) effects were significant, positive, medium-sized, and heterogeneous.
Conclusions: CBT for SUD shows clinical benefit primarily for consumption outcomes, and when tested against non-evidence-based comparators. Residual heterogeneity in effect estimates also suggests effect sizes may vary by study design and population factors.
(Copyright © 2026 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:Molly Magill reports financial support and article publishing charges were provided by National Institute on Alcohol Abuse and Alcoholism. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Grant Information: R01 AA029703 United States AA NIAAA NIH HHS
Contributed Indexing: Keywords: Alcohol treatment; Cognitive-behavioral; Functional outcomes; Substance use treatment; Systematic review
Entry Date(s): Date Created: 20260626 Date Completed: 20260707 Latest Revision: 20260726
Update Code: 20260726
DOI: 10.1016/j.brat.2026.105101
PMID: 42361733
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1873-622X
DOI:10.1016/j.brat.2026.105101