Academic Journal
Microencapsulation of Saskatoon berry polyphenols in inulin/galactooligosaccharide matrices: Effects on bioaccessibility, transepithelial transport, and bioactivity.
| Τίτλος: | Microencapsulation of Saskatoon berry polyphenols in inulin/galactooligosaccharide matrices: Effects on bioaccessibility, transepithelial transport, and bioactivity. |
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| Συγγραφείς: | Lachowicz-Wiśniewska S; Department of Nutrition and Food, University of Kalisz, Pl. W. Bogusławskiego 2, 62-800 Kalisz, Poland; Department of Biotechnology and Food Analysis, Wroclaw University of Economics and Business, Komandorska 118/120 street, 53-345 Wroclaw, Poland. Electronic address: s.lachowicz-wisniewska@uniwersytetkaliski.edu.pl., Miller A; Doctoral School, The Faculty of Medicine and Health Science, University of Kalisz, Pl. W. Bogusławskiego 2, 62-800 Kalisz, Poland. Electronic address: szd.6.2025@uniwersytetkaliski.edu.pl., Świeca M; Laboratory of Enzymology and Bioactive Additives, Department of Biochemistry and Food Chemistry, University of Life Sciences in Lublin, Skromna 8 street, 20-704 Lublin, Poland. Electronic address: michal.swieca@up.lublin.pl., Żurek N; Department of Food Technology and Human Nutrition, University of Rzeszów, Zelwerowicza 9 street, 35-601 Rzeszów, Poland. Electronic address: nzurek@ur.edu.pl., Kapusta I; Department of Food Technology and Human Nutrition, University of Rzeszów, Zelwerowicza 9 street, 35-601 Rzeszów, Poland. Electronic address: ikapusta@ur.edu.pl., Rybak K; Warsaw University of Life Sciences; Institute of Food Sciences; Department of Food Engineering, Nowoursynowska 166 street, 02-787 Warszawa, Poland. Electronic address: katarzyna_rybak@sggw.edu.pl., Sip A; Department of Biotechnology and Food Microbiology, Poznan University of Life Sciences, Wojska Polskiego 48 street, 60-627 Poznan, Poland. Electronic address: anna.sip@up.poznan.pl. |
| Πηγή: | Food chemistry [Food Chem] 2026 Sep 15; Vol. 523, pp. 150069. Date of Electronic Publication: 2026 Jun 17. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE |
| Imprint Name(s): | Publication: Barking : Elsevier Applied Science Publishers Original Publication: Barking, Eng., Applied Science Publishers. |
| Ιατρικοί όροι (MeSH): | Inulin*/chemistry , Inulin*/metabolism , Polyphenols*/chemistry , Polyphenols*/metabolism , Polyphenols*/pharmacology , Fruit*/chemistry , Fruit*/metabolism , Oligosaccharides*/chemistry , Oligosaccharides*/metabolism , Plant Extracts*/chemistry , Plant Extracts*/metabolism , Drug Compounding*/methods , Ananas*/chemistry , Ananas*/metabolism, Prebiotics/analysis ; Antioxidants/chemistry ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Humans ; Caco-2 Cells ; Biological Transport ; Digestion ; Biological Availability |
| Περίληψη: | Polyphenols from Saskatoon berry are promising functional ingredients, yet their value depends on stability during processing, digestion, and transepithelial transfer. This study evaluated freeze-dried inulin (INU) and inulin/galactooligosaccharide (INU/GOS) matrices as carriers for purified Saskatoon berry phenolics. Powders containing 5-25% GOS were characterized by SEM, simulated gastrointestinal digestion, Caco-2 transport, antioxidant and anti-inflammatory assays, prebiotic testing, and cytocompatibility assessment. Initial phenolic retention remained high (88.5-92.7%). Digestion markedly reshaped the profile: apparent total polyphenol bioaccessibility reached 106.2-122.6%, anthocyanins were the least stable fraction, and phenolic acids together with selected flavonols dominated the post-digestive pool. Transepithelial transfer was selective; INU90:GOS10 showed the most favorable overall transfer profile, whereas INU80:GOS20 yielded the highest absolute phenolic content after transport. GOS-containing systems improved selected antioxidant, anti-inflammatory, and prebiotic responses, while pure inulin showed the highest cytocompatibility. Overall, carrier composition modulated the post-digestive functionality of Saskatoon berry polyphenols. (Copyright © 2026 Elsevier Ltd. All rights reserved.) |
| Competing Interests: | Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| Contributed Indexing: | Keywords: Bioaccessibility; Galactooligosaccharides; Inulin; Microencapsulation; Polyphenols; Saskatoon berry; Transepithelial transport; Transport efficiency |
| Substance Nomenclature: | 9005-80-5 (Inulin) 0 (Polyphenols) 0 (Oligosaccharides) 0 (Plant Extracts) 0 (Prebiotics) 0 (Antioxidants) |
| Entry Date(s): | Date Created: 20260622 Date Completed: 20260807 Latest Revision: 20260807 |
| Update Code: | 20260807 |
| DOI: | 10.1016/j.foodchem.2026.150069 |
| PMID: | 42330646 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1873-7072 |
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| DOI: | 10.1016/j.foodchem.2026.150069 |