Academic Journal
Green-Synthesized Zinc Oxide Nanoparticles from Selenicereus grandiflorus Exhibit Potent Nematicidal Activity Against Meloidogyne incognita.
| Τίτλος: | Green-Synthesized Zinc Oxide Nanoparticles from Selenicereus grandiflorus Exhibit Potent Nematicidal Activity Against Meloidogyne incognita. |
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| Συγγραφείς: | Ahmad S; Institute of Biotechnology and Genetic Engineering, The University of Agriculture Peshawar, Peshawar, Pakistan., Ahmad MA; Institute of Biotechnology and Genetic Engineering, The University of Agriculture Peshawar, Peshawar, Pakistan. mianafaq@aup.edu.pk., Ahmad N; Institute of Biotechnology and Genetic Engineering, The University of Agriculture Peshawar, Peshawar, Pakistan., Umer F; Institute of Biotechnology and Genetic Engineering, The University of Agriculture Peshawar, Peshawar, Pakistan., Munir I; Institute of Biotechnology and Genetic Engineering, The University of Agriculture Peshawar, Peshawar, Pakistan., Islam MS; Department of Chemical Engineering, Bangladesh University of Engineering and Technology, Dhaka, 1000, Bangladesh.; Department of Textile Engineering, Daffodil International University, Dhaka, 1341, Bangladesh., Ahmad G; Institute of Biotechnology and Genetic Engineering, The University of Agriculture Peshawar, Peshawar, Pakistan., Ijaz M; Institute of Integrative Biosciences IIB, CECOS University Peshawar, Peshawar, Pakistan., Ditta A; School of Biological Sciences, The University of Western Australia, Perth, WA, 6009, Australia., Iqbal R; Department of Agronomy, Faculty of Agriculture and Environment, The Islamia University of Bahawalpur Pakistan, Bahawalpur, 63100, Pakistan. rashid.iqbal@iub.edu.pk.; Department of Life Sciences, Western Caspian University, Baku, Azerbaijan. rashid.iqbal@iub.edu.pk., Aldahmash B; Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia., Rady A; Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia. ahabdo@ksu.edu.sa. |
| Πηγή: | Current microbiology [Curr Microbiol] 2026 Jun 20; Vol. 83 (8). Date of Electronic Publication: 2026 Jun 20. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Springer International Country of Publication: United States NLM ID: 7808448 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0991 (Electronic) Linking ISSN: 03438651 NLM ISO Abbreviation: Curr Microbiol Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: New York, Springer International. |
| Ιατρικοί όροι (MeSH): | Zinc Oxide*/pharmacology , Zinc Oxide*/chemistry , Tylenchoidea*/drug effects , Antinematodal Agents*/pharmacology , Antinematodal Agents*/chemistry , Nanoparticles*/chemistry, Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Metal Nanoparticles/chemistry ; Animals ; Green Chemistry Technology ; X-Ray Diffraction |
| Περίληψη: | Meloidogyne incognita is a highly destructive plant-parasitic nematode responsible for significant yield losses in a wide range of vegetable crops. The present study investigated the phytochemical profile of Selenicereus grandiflorus and its application in the green synthesis of zinc oxide nanoparticles (ZnO NPs), followed by evaluation of their nematicidal activity against M. incognita. ZnO NPs were synthesized using S. grandiflorus plant extract and characterized using UV-visible spectroscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX), confirming the formation of crystalline ZnO nanoparticles. The synthesized ZnO NPs exhibited a characteristic UV-Vis absorption peak at 336 nm, confirming their formation within the expected range. XRD analysis revealed a highly crystalline structure with an average crystallite size of 10.48 nm, while SEM and TEM observations showed predominantly irregular and spherical morphologies with an average particle size of 24.3 nm. Qualitative phytochemical screening revealed the presence of bioactive constituents, including phenolics, flavonoids, alkaloids, and saponins, which likely contributed to nanoparticle synthesis and bioactivity. Both the crude plant extract and the synthesized ZnO NPs exhibited significant nematicidal effects; however, ZnO NPs demonstrated markedly enhanced efficacy. Exposure to ZnO NPs resulted in a concentration- and time-dependent increase in juvenile mortality, reaching 88.5%, 96.3%, and 99.0% at 24, 48, and 72 h, respectively, at 1000 µg/mL, and 25.83%, 33.5%, and 87.83% at 100 µg/mL. Due to elevated control mortality (> 20%) at 48-72 h, lethal concentration values were calculated using Abbott-corrected 24 h data, yielding LC₅₀ and LC₉₀ values of 354.9 µg/mL (95% CI: 287.0-438.8) and 1410.6 µg/mL (95% CI: 980.8-2029.0), respectively. These findings demonstrate that S. grandiflorus-mediated ZnO NPs possess strong nematicidal activity at sub-phytotoxic concentrations, highlighting their potential as an eco-friendly nanobiotechnological approach for managing plant-parasitic nematodes in sustainable agriculture. (© 2026. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.) |
| Competing Interests: | Declarations. Competing interests: The authors declare no competing interests. Consent for Publication: Not applicable. Ethics Approval and Consent to Participate: This study does not include human or animal subjects. Collection of Plant Material: The plant Selenicereus grandiflorus was cultivated by the University of Agriculture, Peshawar, Pakistan, in the Medicinal Plants Herbarium. The herbarium is located in the Center of the University of Peshawar and the Agriculture University Peshawar Khyber Pakhtunkhwa, Pakistan. Statement on guidelines: All experimental studies and materials used in this research were conducted in accordance with the institutional research ethics policies of The University of Agriculture, Peshawar, Pakistan. As the study did not involve vertebrate animals or human participants, no additional ethical approval was required. |
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| Substance Nomenclature: | SOI2LOH54Z (Zinc Oxide) 0 (Antinematodal Agents) 0 (Plant Extracts) |
| Entry Date(s): | Date Created: 20260620 Date Completed: 20260620 Latest Revision: 20260723 |
| Update Code: | 20260723 |
| DOI: | 10.1007/s00284-026-05032-8 |
| PMID: | 42322390 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1432-0991 |
|---|---|
| DOI: | 10.1007/s00284-026-05032-8 |