Rectal versus groin screening for multidrug-resistant organisms: pathogen-specific diagnostic yield in a tertiary-care hospital.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος:	Rectal versus groin screening for multidrug-resistant organisms: pathogen-specific diagnostic yield in a tertiary-care hospital.
Συγγραφείς:	Myrou A; 1st Propaedeutic Department of Internal Medicine, School of Medicine, Aristotle University of Thessaloniki, AHEPA University General Hospital, Thessaloniki, Greece., Metallidis S; 1st Department of Internal Medicine, School of Medicine, Aristotle University of Thessaloniki, AHEPA University General Hospital, Thessaloniki, Greece., Savopoulos C; 1st Propaedeutic Department of Internal Medicine, School of Medicine, Aristotle University of Thessaloniki, AHEPA University General Hospital, Thessaloniki, Greece.
Πηγή:	Infection control and hospital epidemiology [Infect Control Hosp Epidemiol] 2026 Aug; Vol. 47 (8), pp. 774-777. Date of Electronic Publication: 2026 Jun 18.
Τύπος έκδοσης:	Journal Article; Observational Study
Γλώσσα:	English
Στοιχεία περιοδικού:	Publisher: Cambridge University Press Country of Publication: United States NLM ID: 8804099 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-6834 (Electronic) Linking ISSN: 0899823X NLM ISO Abbreviation: Infect Control Hosp Epidemiol Subsets: MEDLINE
Imprint Name(s):	Publication: Jan. 2015- : Cambridge : Cambridge University Press Original Publication: [Thorofare, N.J. ] : SLACK Inc., c1988-
Ιατρικοί όροι (MeSH):	Groin/microbiology , Rectum/microbiology , Mass Screening/methods , Cross Infection/diagnosis , Cross Infection/microbiology , Drug Resistance, Multiple, Bacterial, Vancomycin-Resistant Enterococci/isolation & purification ; Greece/epidemiology ; Klebsiella pneumoniae/isolation & purification ; Candida auris/isolation & purification ; Pseudomonas aeruginosa/isolation & purification ; Humans ; Tertiary Care Centers ; Prospective Studies
Περίληψη:	Objective: To evaluate the pathogen-specific diagnostic yield of rectal and groin screening sites in a hospital-based multidrug-resistant organism (MDRO) surveillance program. Design: Prospective observational surveillance study. Setting: Tertiary academic hospital in Northern Greece. Patients: Hospitalized patients undergoing active MDRO screening based on predefined infection prevention and control criteria. Methods: A pathogen-focused analysis was conducted using data from a prospective MDRO surveillance program between October 2024 and January 2025. Screening swabs were obtained from the rectum and groin. Target organisms included multidrug-resistant (MDR) Klebsiella pneumoniae, Pseudomonas aeruginosa, vancomycin-resistant enterococci (VRE), Candida auris, and Acinetobacter spp. Pathogen-specific detection yields were calculated for each anatomical site. Results: Among 1,206 screening swabs, 308 (25.5%) were positive for at least one MDRO. Rectal swabs detected 95.8% of Klebsiella pneumoniae (K. pneumoniae) (92/96), 100% of VRE (59/59), and 66.7% of Pseudomonas aeruginosa (46/69). In contrast, 88.9% of Candida auris cases (24/27) were identified exclusively from groin swabs. Reliance on rectal screening alone would have missed nearly 90% of Candida auris carriers, whereas groin-only screening would have failed to detect most K. pneumoniae and all VRE carriers. Conclusions: Anatomical site selection critically influences MDRO surveillance sensitivity. Rectal screening is optimal for MDROs colonizing the gastrointestinal tract, whereas groin sampling is essential for detecting Candida auris. Pathogen-targeted, site-specific surveillance strategies may substantially improve detection efficiency and optimize infection prevention efforts in high-prevalence hospital settings.
Entry Date(s):	Date Created: 20260618 Date Completed: 20260727 Latest Revision: 20260727
Update Code:	20260727
DOI:	10.1017/ice.2026.10489
PMID:	42310987
Βάση Δεδομένων:	MEDLINE

Περιγραφή
ISSN:	1559-6834
DOI:	10.1017/ice.2026.10489