Evaluation of a Point-of-Care Viscoelastic Coagulation Monitor (VCM Vet) and Thromboelastography (TEG) in Bonobos (Pan paniscus).

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Evaluation of a Point-of-Care Viscoelastic Coagulation Monitor (VCM Vet) and Thromboelastography (TEG) in Bonobos (Pan paniscus).
Συγγραφείς: Roeder MM; North Carolina Zoo, Asheboro, North Carolina, USA.; College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA., Bapodra-Villaverde P; Columbus Zoo and Aquarium, Powell, Ohio, USA., Mumm LE; North Carolina Zoo, Asheboro, North Carolina, USA.; College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.; Saint Louis Zoo, St. Louis, Missouri, USA., Lynch AM; College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA., Culbreth LR; College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA., Cabot ML; North Carolina Zoo, Asheboro, North Carolina, USA.; College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA., Georoff TA; North Carolina Zoo, Asheboro, North Carolina, USA.; College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA., Minter LJ; North Carolina Zoo, Asheboro, North Carolina, USA.; College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.
Πηγή: Journal of medical primatology [J Med Primatol] 2026 Aug; Vol. 55 (4), pp. e70094.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Wiley Country of Publication: Denmark NLM ID: 0320626 Publication Model: Print Cited Medium: Internet ISSN: 1600-0684 (Electronic) Linking ISSN: 00472565 NLM ISO Abbreviation: J Med Primatol Subsets: MEDLINE
Imprint Name(s): Publication: Copenhagen : Wiley
Original Publication: Basel, New York, Karger.
Ιατρικοί όροι (MeSH): Thrombelastography*/veterinary , Thrombelastography*/instrumentation , Pan paniscus*/blood , Point-of-Care Systems* , Blood Coagulation*, Blood Coagulation Tests/veterinary ; Blood Coagulation Tests/instrumentation ; Animals ; Female ; Male
Περίληψη: Introduction: Bonobos (Pan paniscus) are endangered and uncommon in managed care. Prothrombotic and hypofibrinolytic states are encountered with cardiovascular disease, ischemic stroke, and neoplasia.
Materials and Methods: Twelve bonobos from one institution were evaluated during anesthetized exams. Samples were analyzed on a VCM Vet analyzer, obtaining results within 1 h.
Results: VCM parameters (median [IQR]) reflected clot formation: clot time 300 s [265-332], clot formation time 97 s [82-107], α-angle 65° [63-69]; clot strength: maximum clot formation 50 units [47-52], amplitude 10 min 40 units [35-44], and amplitude 20 min 47 units [43-51]; and clot lysis: index 30 min 99.97% [99.95-100.00] and index 45 min 98.10% [97.50-99.20]. VCM was compared to thromboelastography and coagulation testing.
Discussion: Bonobos were hypercoagulable when compared to canine reference intervals, consistent with chimpanzees. Bonobos medicated for hypertension in this study were hypocoagulable compared to normotensive individuals.
(© 2026 The Author(s). Journal of Medical Primatology published by John Wiley & Sons Ltd.)
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Contributed Indexing: Keywords: bonobo; hypertension; pan; viscoelastic coagulation monitoring
Entry Date(s): Date Created: 20260618 Date Completed: 20260618 Latest Revision: 20260926
Update Code: 20260926
PubMed Central ID: PMC13276012
DOI: 10.1111/jmp.70094
PMID: 42310866
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1600-0684
DOI:10.1111/jmp.70094