Academic Journal
Advances in the application of photobiomodulation technology in spinal cord injury rehabilitation.
| Τίτλος: | Advances in the application of photobiomodulation technology in spinal cord injury rehabilitation. |
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| Συγγραφείς: | Yang L; Department of Rehabilitation Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian 106011, China; College of Health-Preservation and Wellness, Dalian Medical University, Dalian 106044, China., Liu J; Department of Rehabilitation Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian 106011, China; College of Health-Preservation and Wellness, Dalian Medical University, Dalian 106044, China., Qiao Q; Department of Rehabilitation Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian 106011, China; College of Health-Preservation and Wellness, Dalian Medical University, Dalian 106044, China., Zhou J; Department of Rehabilitation Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian 106011, China., Zhang Z; Department of Rehabilitation Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian 106011, China., Gao Y; Department of Rehabilitation Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian 106011, China. Electronic address: z1590868@sina.cn., Liu Y; Department of Rehabilitation Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian 106011, China; College of Health-Preservation and Wellness, Dalian Medical University, Dalian 106044, China. Electronic address: fuwa52008@126.com. |
| Πηγή: | Experimental neurology [Exp Neurol] 2026 Oct; Vol. 404, pp. 115869. Date of Electronic Publication: 2026 Jun 15. |
| Τύπος έκδοσης: | Journal Article; Review |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Academic Press Country of Publication: United States NLM ID: 0370712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2430 (Electronic) Linking ISSN: 00144886 NLM ISO Abbreviation: Exp Neurol Subsets: MEDLINE |
| Imprint Name(s): | Publication: Orlando Fl : Academic Press Original Publication: New York. |
| Ιατρικοί όροι (MeSH): | Spinal Cord Injuries*/rehabilitation , Spinal Cord Injuries*/physiopathology , Low-Level Light Therapy*/methods , Low-Level Light Therapy*/trends , Recovery of Function*/physiology, Nerve Regeneration/physiology ; Humans ; Animals ; Red Light |
| Περίληψη: | Spinal cord injury (SCI) is a severe central nervous system trauma that often leads to irreversible motor, sensory, and autonomic dysfunction, posing significant challenges to both patients' quality of life and the public healthcare system. Photobiomodulation (PBM), a non-invasive, low-risk physical therapy technique, activates intracellular photoacceptors with specific wavelengths of light (primarily near-infrared and red light). By regulating pathways involved in oxidative stress, inflammation, and neural repair, PBM offers a novel approach to SCI rehabilitation. This paper systematically reviews the mechanisms of PBM and summarizes the evidence for its application in the recovery of motor, sensory, and reproductive functions, as well as in autonomic dysfunction following SCI. What's more, it analyzes the efficacy and safety of PBM in combination with other interventions and outlines future research priorities in this field, aiming to guide the clinical translation and application of PBM in SCI rehabilitation. (Copyright © 2026. Published by Elsevier Inc.) |
| Competing Interests: | Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:(Yong Liu reports financial support was provided by Dalian Association of Science and Technology. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.) |
| Contributed Indexing: | Keywords: Functional recovery; Neural regeneration; Neural repair; Photobiomodulation; Spinal cord injury |
| Entry Date(s): | Date Created: 20260615 Date Completed: 20260715 Latest Revision: 20260715 |
| Update Code: | 20260715 |
| DOI: | 10.1016/j.expneurol.2026.115869 |
| PMID: | 42297204 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1090-2430 |
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| DOI: | 10.1016/j.expneurol.2026.115869 |