Academic Journal
Intelligent logic-gate-integrated capillary fluorescence imprinted microarray sensor for rapid simultaneous detection of multiple endocrine disrupting compounds.
| Τίτλος: | Intelligent logic-gate-integrated capillary fluorescence imprinted microarray sensor for rapid simultaneous detection of multiple endocrine disrupting compounds. |
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| Συγγραφείς: | Ma A; School of Pharmaceutical Sciences, Jishou University, Hunan, 416000, PR China; Key Laboratory of Medicinal Resources Chemistry and Pharmacology in Wuling Mountainous of Hunan Province College, Jishou University, Jishou, 416000, PR China., Liao Z; School of Pharmaceutical Sciences, Jishou University, Hunan, 416000, PR China; Key Laboratory of Medicinal Resources Chemistry and Pharmacology in Wuling Mountainous of Hunan Province College, Jishou University, Jishou, 416000, PR China., Wang R; School of Pharmaceutical Sciences, Jishou University, Hunan, 416000, PR China; Key Laboratory of Medicinal Resources Chemistry and Pharmacology in Wuling Mountainous of Hunan Province College, Jishou University, Jishou, 416000, PR China., Wu Q; School of Pharmaceutical Sciences, Jishou University, Hunan, 416000, PR China., Wu J; College of Chemistry and Chemical Engineering, Jishou University, Hunan, 416000, PR China., Zhao K; College of Chemistry and Chemical Engineering, Jishou University, Hunan, 416000, PR China., Yang Z; College of Chemistry and Chemical Engineering, Jishou University, Hunan, 416000, PR China., Zhang Z; School of Pharmaceutical Sciences, Jishou University, Hunan, 416000, PR China; College of Chemistry and Chemical Engineering, Jishou University, Hunan, 416000, PR China; Key Laboratory of Medicinal Resources Chemistry and Pharmacology in Wuling Mountainous of Hunan Province College, Jishou University, Jishou, 416000, PR China. Electronic address: zhaohuizhang77@163.com. |
| Πηγή: | Talanta [Talanta] 2026 Dec 01; Vol. 310, pp. 130147. Date of Electronic Publication: 2026 Jun 12. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2984816R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3573 (Electronic) Linking ISSN: 00399140 NLM ISO Abbreviation: Talanta Subsets: MEDLINE |
| Imprint Name(s): | Publication: Amsterdam : Elsevier Original Publication: Oxford : Pergamon Press |
| Ιατρικοί όροι (MeSH): | Endocrine Disruptors*/analysis , Microarray Analysis*/methods, Benzhydryl Compounds/analysis ; Phenols/analysis ; Dibutyl Phthalate/analysis ; Food Contamination/analysis ; Bisphenol A Compounds ; Fluorescence ; Spectrometry, Fluorescence ; Molecular Imprinting |
| Περίληψη: | Endocrine disrupting compounds (EDCs) extensively distributed in the environment have imposed severe hazards on ecological systems and human health owing to their persistence, bioaccumulation, and toxicity. Herein, a capillary fluorescence imprinted microarray sensor integrated with intelligent logic gate was constructed to achieve the rapid visual identification and quantification of three EDCs involving dibutyl phthalate (DBP), bisphenol A (BPA), triphenyl phosphate (TPHP), and their mixtures. Three molecularly imprinted polymers were respectively controllably modified onto a capillary inner surface with static gas-driven coating approach to obtain a golden-hoop-type microarray sensor, generating specific fluorescence responses and distinguishable color variations toward the three target EDCs. By integrating fluorescence sensing with one-step image analysis, the capillary fluorescence microarray sensor achieved a rapid response toward DBP, BPA, and TPHP within 3.5 min, with favorable sensitivities of 0.65, 7.2, and 4.6 nM, respectively. Furthermore, this capillary fluorescence microarray sensor successfully recognized DBP, BPA and TPHP in spiked biological and food matrices. The proposed multi-segment microarray sensing strategy combined with intelligent logic gates achieves the improvement in anti-interference ability, detection intelligence and practicability, providing a promising strategy for the on-site simultaneous rapid detection of multiple EDCs with a microvolume (50 μL/time) in real samples. (Copyright © 2026 Elsevier B.V. All rights reserved.) |
| Competing Interests: | Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| Contributed Indexing: | Keywords: Endocrine disrupting compounds; Fluorescence capillary; Imprinted; Microarray sensor; One-click image processing |
| Substance Nomenclature: | 0 (Endocrine Disruptors) 0 (Bisphenol A Compounds) MLT3645I99 (bisphenol A) 0 (Benzhydryl Compounds) 0 (Phenols) 2286E5R2KE (Dibutyl Phthalate) |
| Entry Date(s): | Date Created: 20260615 Date Completed: 20260818 Latest Revision: 20260818 |
| Update Code: | 20260818 |
| DOI: | 10.1016/j.talanta.2026.130147 |
| PMID: | 42296872 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1873-3573 |
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| DOI: | 10.1016/j.talanta.2026.130147 |