Controlled-release herbicide spheres: co-crystallization of 2,4-dichlorophenoxyacetic acid with l-menthol via green oiling-out process for low leaching and high activity.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Controlled-release herbicide spheres: co-crystallization of 2,4-dichlorophenoxyacetic acid with l-menthol via green oiling-out process for low leaching and high activity.
Συγγραφείς: Zhang X; Information Science and Technology, Qingdao University of Science and Technology, Qingdao, China., Fang L; Information Science and Technology, Qingdao University of Science and Technology, Qingdao, China., Wang H; Information Science and Technology, Qingdao University of Science and Technology, Qingdao, China., Xiao Y; School of Plant Protection, Anhui Agricultural University, Hefei, China., Wang D; Information Science and Technology, Qingdao University of Science and Technology, Qingdao, China., Hao Z; Ping'an Community Hospital, Jinan, China., Gong J; School of Chemical Engineering and Technology, State Key Laboratory of Chemical Engineering, Tianjin University, Tianjin, China.
Πηγή: Pest management science [Pest Manag Sci] 2026 Oct; Vol. 82 (10), pp. 9764-9777. Date of Electronic Publication: 2026 Jun 12.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Published for SCI by Wiley Country of Publication: England NLM ID: 100898744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-4998 (Electronic) Linking ISSN: 1526498X NLM ISO Abbreviation: Pest Manag Sci Subsets: MEDLINE
Imprint Name(s): Original Publication: West Sussex, UK : Published for SCI by Wiley, c2000-
Ιατρικοί όροι (MeSH): 2,4-Dichlorophenoxyacetic Acid*/chemistry , Herbicides*/chemistry , Herbicides*/pharmacology , Menthol*/chemistry, Delayed-Action Preparations/chemistry ; Crystallization ; Weed Control
Περίληψη: Background: Excessive pesticide soil leaching (>99% loss) poses a critical environmental challenge. This study aimed to develop carrier free, slow release herbicide particles by integrating crystal engineering and spherical particle technology.
Results: A 2,4 dichlorophenoxyacetic acid-l menthol cocrystal was synthesized solvent free into spherical particles (D50 = 100-600 μm). These cocrystal particles reduced solubility by 21.6%, decreased dissolution rate by >50%, and reduced soil leaching by up to 93%, eliminating the need for carriers and avoiding secondary pollution. The release mechanism was governed by a multiscale diffusion limited process: enhanced hydrogen bonding networks elevated lattice energy, while solution mediated recrystallization transformed nanofibrous microstructures into diffusion restricting lamellar domains. Kinetic modeling indicated a transition from Fickian to hindered diffusion. Biological validation demonstrated superior weed control efficacy against chicory and shepherd's purse.
Conclusion: This integrated approach establishes a sustainable paradigm for precision agrochemical delivery by significantly reducing environmental leaching while maintaining high herbicidal activity. © 2026 Society of Chemical Industry.
(© 2026 Society of Chemical Industry.)
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Grant Information: the National Natural Science Foundation of China; the Shandong Province Higher Education Institutions Youth Innovation and Technology Support Program; the Shandong Provincial Natural Science Foundation
Contributed Indexing: Keywords: cocrystal engineering; diffusion‐limited release; oiling‐out crystallization; soil leaching mitigation; sustainable agrochemicals
Substance Nomenclature: 2577AQ9262 (2,4-Dichlorophenoxyacetic Acid)
0 (Herbicides)
1490-04-6 (Menthol)
0 (Delayed-Action Preparations)
Entry Date(s): Date Created: 20260613 Date Completed: 20260911 Latest Revision: 20260913
Update Code: 20260913
PubMed Central ID: PMC13569152
DOI: 10.1002/ps.71011
PMID: 42286805
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1526-4998
DOI:10.1002/ps.71011