Academic Journal
Tendencies in the association between fatigue and quality of life in terminally ill patients with cancer admitted to a palliative care unit.
| Title: | Tendencies in the association between fatigue and quality of life in terminally ill patients with cancer admitted to a palliative care unit. |
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| Authors: | Matsuda M; Graduate School of Health Sciences, Department of Nursing, Doctoral Program, Niigata Universityhttps://ror.org/04ww21r56, Niigata, Japan., Koyama Y; Graduate School of Health Sciences, Niigata University, Niigata, Japan., Seki N; Graduate School of Health Sciences, Niigata University, Niigata, Japan., Sakai S; Graduate School of Health Sciences, Niigata University, Niigata, Japan. |
| Source: | Palliative & supportive care [Palliat Support Care] 2026 Jun 09; Vol. 24, pp. e161. Date of Electronic Publication: 2026 Jun 09. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Cambridge University Press Country of Publication: England NLM ID: 101232529 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-9523 (Electronic) Linking ISSN: 14789515 NLM ISO Abbreviation: Palliat Support Care Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Cambridge : Cambridge University Press, c2003- |
| MeSH Terms: | Quality of Life*/psychology , Fatigue*/psychology , Fatigue*/etiology , Fatigue*/complications , Neoplasms*/psychology , Neoplasms*/complications , Palliative Care*/methods , Palliative Care*/psychology , Palliative Care*/standards , Terminally Ill*/psychology, Psychometrics/instrumentation ; Psychometrics/methods ; Humans ; Female ; Male ; Surveys and Questionnaires ; Aged ; Middle Aged ; Aged, 80 and over ; Adult |
| Abstract: | Background: Cancer-related fatigue (CRF) is a distressing symptom in terminally ill patients with cancer. While many studies have been conducted on the relationship between fatigue and quality of life (QOL) among patients undergoing treatment, only a few have been conducted to measure fatigue from multiple perspectives or clarify its impact on patients in advanced stages or those receiving palliative care. Objectives: To examine the impact of fatigue on QOL in terminally ill patients with cancer, using a questionnaire that measures CRF from 3 perspectives. Methods: CRF and QOL were measured using the Cancer Fatigue Scale (CFS) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 15 Palliative (EORTCQLQ-C15-PAL), respectively, and the correlation between them was evaluated. Web-based questionnaires were completed by patients receiving hospice and palliative care. Significance of Results: Twenty-nine participants provided valid responses. Median CFS and global health status/QOL scores were as follows: total fatigue 25.0, physical fatigue 11.0, affective fatigue 9.0, cognitive fatigue 5.0, and global health status/QOL 50.0. QOL showed significant correlations with total fatigue (rs = -0.44, p = 0.017, 95% CI: -0.70, -0.09) and physical fatigue (rs = -0.38, p = 0.038, 95% CI: -0.66, -0.02), but none with affective fatigue (rs = -0.02, p = 0.917, 95% CI: -0.38, 0.35) and cognitive fatigue (rs = -0.33, p = 0.074, 95% CI: -0.63, 0.03). Conclusions: Of the 3 aspects of fatigue, physical fatigue may be most closely related to QOL; however, its accurate assessment may depend on the scale used. Therefore, it is necessary to select an appropriate scale for patients with terminal cancer. |
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| Contributed Indexing: | Keywords: Cancer-related fatigue; assessment; physical fatigue; quality of life; terminal cancer |
| Entry Date(s): | Date Created: 20260609 Date Completed: 20260609 Latest Revision: 20260813 |
| Update Code: | 20260813 |
| PubMed Central ID: | PMC13280580 |
| DOI: | 10.1017/S1478951526102740 |
| PMID: | 42262215 |
| Database: | MEDLINE |
| ISSN: | 1478-9523 |
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| DOI: | 10.1017/S1478951526102740 |