Academic Journal
Neuroelectrophysiological effects of Wuqinxi exercise on reactive inhibition deficits in Parkinson's disease.
| Τίτλος: | Neuroelectrophysiological effects of Wuqinxi exercise on reactive inhibition deficits in Parkinson's disease. |
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| Συγγραφείς: | Wang Z; School of Sport and Health Science, Xi'an Physical Education University, Xi'an, China; School of Psychology, Shanghai University of Sport, Shanghai, China., Li Y; School of Psychology, Shanghai University of Sport, Shanghai, China; Department of Chinese Medicine Nursing, School of Nursing, Anhui University of Chinese Medicine, Hefei, China., Wei J; Henan University of Science and Technology Sports Institute, Luoyang, China., Song Y; School of Psychology, Shanghai University of Sport, Shanghai, China., Chen J; School of Psychology, Shanghai University of Sport, Shanghai, China., Tan X; Faculty of Health Sciences and Sports, Macao Polytechnic University, Rua de Luis Gonzaga Gomes, Macao Special Administrative Region of China., Zhang J; School of Psychology, Shanghai University of Sport, Shanghai, China. Electronic address: zhangjian@sus.edu.cn. |
| Πηγή: | Psychology of sport and exercise [Psychol Sport Exerc] 2026 Sep; Vol. 86, pp. 103162. Date of Electronic Publication: 2026 May 16. |
| Τύπος έκδοσης: | Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101088724 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5476 (Electronic) Linking ISSN: 18785476 NLM ISO Abbreviation: Psychol Sport Exerc Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: [Amsterdam ; New York : Elsevier |
| Ιατρικοί όροι (MeSH): | Parkinson Disease*/physiopathology , Parkinson Disease*/therapy , Parkinson Disease*/psychology , Motor Cortex*/physiopathology , Motor Cortex*/physiology , Exercise Therapy*/methods , Reactive Inhibition*, Reaction Time/physiology ; Dorsolateral Prefrontal Cortex/physiopathology ; Dorsolateral Prefrontal Cortex/physiology ; Humans ; Female ; Male ; Aged ; Transcranial Magnetic Stimulation ; Middle Aged |
| Περίληψη: | Objective: Motor inhibition deficits in Parkinson's disease (PD) are linked to functional alterations in the frontal-basal ganglia circuit, notably excessive interhemispheric inhibition from the right dorsolateral prefrontal cortex (DLPFC) onto the left primary motor cortex (M1). Although Wuqinxi-a traditional Chinese exercise-has been shown to ameliorate motor symptoms in PD, its potential to remediate motor inhibition impairments via modulation of cortical interhemispheric interactions remains unresolved. Methods: Forty-seven PD patients were randomly assigned to either a Wuqinxi group or a stretching control group for a 24-week intervention, completing 90mins sessions three times per week. We used dual-site paired-pulse transcranial magnetic stimulation (ppTMS) to combine stop-signal tasks to examine the electrophysiological and motor inhibition changes pre and post intervention. Results: Compared with pre-intervention measures, PD patients in the Wuqinxi group exhibited a significant reduction in interhemispheric inhibitory interaction between the right DLPFC and left M1, concomitant with a pronounced decrease in stop signal reaction time (SSRT). Conclusions: 24 weeks of Wuqinxi practice attenuate excessive interhemispheric inhibition from the right DLPFC to the left M1 in PD patients, thereby alleviating impaired reactive inhibition capacity. (Copyright © 2026 Elsevier Ltd. All rights reserved.) |
| Competing Interests: | Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| Contributed Indexing: | Keywords: Dorsolateral prefrontal cortex; Interhemispheric interaction; Motor inhibition; Primary motor cortex; Stop signal reaction time |
| Entry Date(s): | Date Created: 20260516 Date Completed: 20260722 Latest Revision: 20260903 |
| Update Code: | 20260904 |
| DOI: | 10.1016/j.psychsport.2026.103162 |
| PMID: | 42142853 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1878-5476 |
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| DOI: | 10.1016/j.psychsport.2026.103162 |