Academic Journal
Technologies in clinical neurophysiology for brain-body interfacing: IFCN handbook chapter.
| Τίτλος: | Technologies in clinical neurophysiology for brain-body interfacing: IFCN handbook chapter. |
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| Συγγραφείς: | Cimolato A; Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Wien, Austria; Comprehensive Center for Artificial Intelligence in Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Wien, Austria., Sparapani A; Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Wien, Austria; Comprehensive Center for Artificial Intelligence in Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Wien, Austria., Raspopovic S; Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Wien, Austria; Comprehensive Center for Artificial Intelligence in Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Wien, Austria. Electronic address: stanisa.raspopovic@meduniwien.ac.at. |
| Πηγή: | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology [Clin Neurophysiol] 2026 Oct; Vol. 190, pp. 2111913. Date of Electronic Publication: 2026 May 03. |
| Τύπος έκδοσης: | Journal Article; Review |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 100883319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8952 (Electronic) Linking ISSN: 13882457 NLM ISO Abbreviation: Clin Neurophysiol Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Amsterdam : Elsevier, c1999- |
| Ιατρικοί όροι (MeSH): | Brain*/physiology , Neurophysiology*/methods , Brain-Computer Interfaces*, Humans ; Animals |
| Περίληψη: | Interfacing the brain with the body represents a central challenge in contemporary clinical neurophysiology. Neurological injuries such as stroke, spinal cord injury, and limb loss disrupt the bidirectional flow of information between central and peripheral circuits, impairing voluntary movement, sensation, and embodiment. Clinical neurophysiology provides the quantitative and methodological foundation necessary to understand and modulate this communication. By characterizing neural signals across cortical, spinal, and peripheral levels, it establishes the principles required to decode and stimulate the nervous system. Traditionally focused on diagnostic assessment through electrophysiological techniques, clinical neurophysiology provides the conceptual and technical basis for active brain-body interfacing. Within this framework, interfacing encompasses both "reading" and "writing" neural information. Decoding refers to the extraction of meaningful variables (e.g., movement intention) from neural activity. Actuation refers to the targeted delivery of electrical stimulation or mechanical assistance to modulate neural circuits or generate movement and sensation. This chapter reviews neurophysiology-based strategies across multiple neuroanatomical levels and how integrating decoding and actuation into closed-loop architectures enables the re-establishment of bidirectional information flow. By coupling neural control with functional feedback, these systems enhance control precision, support embodiment, and engage activity-dependent plasticity, providing a mechanistically grounded strategy for modulating disrupted neural communication. (Copyright © 2026 The Authors. Published by Elsevier B.V. All rights reserved.) |
| Competing Interests: | Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| Contributed Indexing: | Keywords: Brain-body interface; Closed-loop control; Cortical; Decoding; Electrical stimulation; Neurophysiology; Neuroprosthetics; Peripheral nerve; Sensory feedback; Spinal |
| Entry Date(s): | Date Created: 20260511 Date Completed: 20260812 Latest Revision: 20260812 |
| Update Code: | 20260813 |
| DOI: | 10.1016/j.clinph.2026.2111913 |
| PMID: | 42115034 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1872-8952 |
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| DOI: | 10.1016/j.clinph.2026.2111913 |