Academic Journal
Prevalence and determinants of parental refusal of human papillomavirus vaccination in Morocco: A multicenter cross-sectional study.
| Τίτλος: | Prevalence and determinants of parental refusal of human papillomavirus vaccination in Morocco: A multicenter cross-sectional study. |
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| Συγγραφείς: | Essayagh T; Hassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et ingénierie biomédicales, biophysique et santé, Settat, Morocco., Essayagh M; Office National de Sécurité Sanitaire des produits Alimentaires, Meknès, Morocco., Nmila K; Hassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et ingénierie biomédicales, biophysique et santé, Settat, Morocco., Slibani H; Hassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et ingénierie biomédicales, biophysique et santé, Settat, Morocco., Hachimi SE; Hassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et ingénierie biomédicales, biophysique et santé, Settat, Morocco., Boukhari ME; Hassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et ingénierie biomédicales, biophysique et santé, Settat, Morocco., Lemriss H; Hassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et ingénierie biomédicales, biophysique et santé, Settat, Morocco., Lemriss S; Laboratoire of Research and Medical Analysis of Gendarmerie Royale, Department of Biosafety, Rabat, Morocco., Zadran R; National Infectious Diseases Hospital Laboratory, Kabul, Afghanistan., Tigaidi H; University of Kordofan, Faculty of Public and environmental Health, Elobeid, Sudan., Essayagh S; Hassan First University of Settat, Faculté des Sciences et Techniques, Laboratoire Agroalimentaire et Santé, Settat, Morocco. |
| Πηγή: | PloS one [PLoS One] 2026 May 06; Vol. 21 (5), pp. e0348586. Date of Electronic Publication: 2026 May 06 (Print Publication: 2026). |
| Τύπος έκδοσης: | Journal Article; Multicenter Study |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: San Francisco, CA : Public Library of Science |
| Ιατρικοί όροι (MeSH): | Papillomavirus Vaccines*/administration & dosage , Parents*/psychology , Papillomavirus Infections*/prevention & control , Human Papillomavirus Viruses*/immunology , Vaccination*/psychology , Vaccination Refusal*/statistics & numerical data , Vaccination Refusal*/psychology , Uterine Cervical Neoplasms*/prevention & control , Uterine Cervical Neoplasms*/virology, Morocco/epidemiology ; Humans ; Female ; Cross-Sectional Studies ; Adult ; Adolescent ; Health Knowledge, Attitudes, Practice ; Prevalence ; Child ; Middle Aged ; Risk Factors |
| Περίληψη: | Introduction: Vaccination against the human papillomavirus (HPV) is an effective way to avert cervical cancer. However, acceptance in Morocco remains inadequate. The aim of this study was to measure the prevalence of parental HPV vaccine refusal and the risk factors associated with it. Methods: Between 3 March and 30 September 2025, a multicenter cross-sectional survey was conducted among Moroccan parents of girls aged 11-14 who attended health facilities. The study looked at sociodemographic factors, knowledge regarding HPV and cervical cancer, and vaccination attitudes. A multivariate logistic regression analysis was used to identify risk factors for vaccination refusal. Results: The research included 1,444 participants with an average age of 37.7 ± 6.6 years. Of them, 415 refused HPV vaccination for their daughters, resulting in a prevalence of 28.7%. Vaccine refusal was substantially related to higher educational levels, lower income, less faith in the healthcare system, less knowledge about cervical cancer and its symptoms, and insufficient information regarding the HPV vaccine as seen by the media. Refusal was also associated with a poor perception of the seriousness of HPV infection, fear of vaccinating daughters, noncompliance with past vaccination schedules, difficulties accessing health centers, and a lack of recommendations from healthcare professionals. In contrast, refusal was inversely associated with parents who were uninformed of the proper number of vaccination doses or uninformed regarding the availability of the HPV vaccine at health centers or who feared the vaccine may cause an adverse reaction. Conclusion: Parental refusal of HPV vaccination is still a substantial obstacle. To increase acceptability and enhance cervical cancer prevention in Morocco, it is critical to expand communication strategy, boost public knowledge, and assure active participation of healthcare professionals. (Copyright: © 2026 Essayagh et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.) |
| Competing Interests: | The authors have declared that no competing interests exist. |
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| Substance Nomenclature: | 0 (Papillomavirus Vaccines) |
| Entry Date(s): | Date Created: 20260506 Date Completed: 20260716 Latest Revision: 20260825 |
| Update Code: | 20260825 |
| PubMed Central ID: | PMC13148701 |
| DOI: | 10.1371/journal.pone.0348586 |
| PMID: | 42090367 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0348586 |