Academic Journal
Sporosarcina pasteurii urease gene expression regulation mechanism overcomes urease inhibition by hydrocarbons.
| Title: | Sporosarcina pasteurii urease gene expression regulation mechanism overcomes urease inhibition by hydrocarbons. |
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| Authors: | Comadran-Casas C; James Watt School of Engineering, College of Science and Engineering, Department of Infrastructure and Environment, the University of Glasgow, Glasgow, UK. Electronic address: Carla.ComadranCasas@glasgow.ac.uk., Cholet F; James Watt School of Engineering, College of Science and Engineering, Department of Infrastructure and Environment, the University of Glasgow, Glasgow, UK., Ogundero A; James Watt School of Engineering, College of Science and Engineering, Department of Infrastructure and Environment, the University of Glasgow, Glasgow, UK., Poursat BAJ; James Watt School of Engineering, College of Science and Engineering, Department of Infrastructure and Environment, the University of Glasgow, Glasgow, UK., Smith CJ; James Watt School of Engineering, College of Science and Engineering, Department of Infrastructure and Environment, the University of Glasgow, Glasgow, UK., Sloan WT; James Watt School of Engineering, College of Science and Engineering, Department of Infrastructure and Environment, the University of Glasgow, Glasgow, UK., Bass AM; School of Geographical & Earth Sciences, College of Science and Engineering, University of Glasgow, Glasgow, UK., MacDonald J; School of Geographical & Earth Sciences, College of Science and Engineering, University of Glasgow, Glasgow, UK., Unluer C; Department of Civil Engineering and Management, University of Manchester, Manchester, UK., Gauchotte-Lindsay C; James Watt School of Engineering, College of Science and Engineering, Department of Infrastructure and Environment, the University of Glasgow, Glasgow, UK. |
| Source: | Journal of hazardous materials [J Hazard Mater] 2026 Jun 15; Vol. 511, pp. 142148. Date of Electronic Publication: 2026 Apr 21. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9422688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3336 (Electronic) Linking ISSN: 03043894 NLM ISO Abbreviation: J Hazard Mater Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Amsterdam : Elsevier |
| MeSH Terms: | Sporosarcina*/genetics , Sporosarcina*/drug effects , Sporosarcina*/enzymology , Sporosarcina*/growth & development , Urease*/genetics , Urease*/antagonists & inhibitors , Urease*/metabolism , Hydrocarbons*/pharmacology , Hydrocarbons*/toxicity , Gene Expression Regulation, Bacterial*/drug effects , Gene Expression Regulation, Enzymologic*/drug effects |
| Abstract: | Hydrocarbons have been shown to both inhibit and enhance soil bacterial ureolysis. This suggests that indigenous ureolytic communities may perform better in the presence of contaminants than in their absence, pointing to an unresolved adaptation mechanism. In this study we conducted a molecular investigation on ureC gene expression of model Microbial-Induced Calcite Precipitation (MICP) bacterium Sporosarcina pasteurii during growth under increasing concentrations of hydrocarbon water extracts obtained from a coal tar polluted soil to ensure environmental relevance. Results indicated S. pasteurii ability to carry out ureolysis from low initial cell concentration (OD (Copyright © 2026 The Authors. Published by Elsevier B.V. All rights reserved.) |
| Competing Interests: | Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Carla Comadran Casas reports financial support was provided by UK Research and Innovation Natural Environment Research Council. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| Contributed Indexing: | Keywords: Hydrocarbons; Microbial-induced calcite precipitation; Soil; Sporosarcina pasteurii; Urea hydrolysis; ureC gene expression |
| Substance Nomenclature: | EC 3.5.1.5 (Urease) 0 (Hydrocarbons) |
| SCR Organism: | Sporosarcina pasteurii |
| Entry Date(s): | Date Created: 20260505 Date Completed: 20260716 Latest Revision: 20260716 |
| Update Code: | 20260716 |
| DOI: | 10.1016/j.jhazmat.2026.142148 |
| PMID: | 42085786 |
| Database: | MEDLINE |
| ISSN: | 1873-3336 |
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| DOI: | 10.1016/j.jhazmat.2026.142148 |