Academic Journal
Use of sodium thiosulfate in prevention of aki in oncologic patient that underwent hipec (Hyperthermic Intraperitoneal Chemotherapy) with Cisplatin: a Case Report.
| Τίτλος: | Use of sodium thiosulfate in prevention of aki in oncologic patient that underwent hipec (Hyperthermic Intraperitoneal Chemotherapy) with Cisplatin: a Case Report. |
|---|---|
| Συγγραφείς: | Sanda VC; Department of Emergency Medicine, Critical Care Medicine and Trauma, Sapienza University, Rome, Italy., Ranieri VM; IRCCS Azienda Ospedaliero Universitaria di Bologna, University Hospital Sant'Orsola-Malpighi, Respiratory and Critical Care Unit, Bologna, Italy., Miccini M; Department of Surgery, Sapienza University of Rome, Rome, Italy., Biacchi D; Department of Surgery, Sapienza University of Rome, Rome, Italy., Crocetti D; Department of Surgery, Sapienza University of Rome, Rome, Italy., Guerra C; Department of Anesthesiology and Palliative Care, Sapienza University, Rome, Italy., Fanello G; UOC Gastroenterologia ed Endoscopia Digestiva, Azienda Ospedaliera 'San Giovanni-Addolorata', 00184 Rome, Italy., Accarpio F; Department of Surgery, Sapienza University of Rome, Rome, Italy., Cavallaro G; Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University, Rome, Italy., Spalice E; Department of Surgery, Sapienza University of Rome, Rome, Italy., Gazzanelli S; Department of Anesthesiology and Palliative Care, Sapienza University, Rome, Italy. |
| Πηγή: | La Clinica terapeutica [Clin Ter] 2026 May-Jun; Vol. 177 (3), pp. 385-387. |
| Τύπος έκδοσης: | Case Reports; Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Societa Editrice Universo Country of Publication: Italy NLM ID: 0372604 Publication Model: Print Cited Medium: Internet ISSN: 1972-6007 (Electronic) Linking ISSN: 00099074 NLM ISO Abbreviation: Clin Ter Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Roma : Societa Editrice Universo |
| Ιατρικοί όροι (MeSH): | Cisplatin*/administration & dosage , Cisplatin*/therapeutic use , Cisplatin*/adverse effects , Thiosulfates*/therapeutic use , Hyperthermic Intraperitoneal Chemotherapy*/adverse effects , Ovarian Neoplasms*/drug therapy , Ovarian Neoplasms*/therapy , Antineoplastic Agents*/administration & dosage , Antineoplastic Agents*/therapeutic use , Antineoplastic Agents*/adverse effects , Acute Kidney Injury*/prevention & control , Acute Kidney Injury*/chemically induced , Adenocarcinoma*/drug therapy , Adenocarcinoma*/therapy, Humans ; Female ; Aged ; Combined Modality Therapy |
| Περίληψη: | Abstract: Ovarian cancer is among the most common cancers diagnosed in women. It is the eighth most common cause of cancer death, with five-year survival rates below 45%. It is fundamental to have weapons and strategies to treat this type of cancer. Cisplatin is a well-known anticancer molecule that works by damaging the DNA of cancer cells. It is used in a variety of tumors such as testicular, bladder, lung and mostly in ovarian cancer. We present a case report of a 72-year-old woman diagnosed with ovarian adenocarcinoma. She underwent surgery in another hospital, and the uterus, both ovaries and the left kidney were removed, as it was infiltrated by the cancer. HIPEC is a technique that permits delivery of the anticancer drug directly to its active site. It has been demonstrated that cytoreduction + HIPEC with cisplatin has a better outcome in terms of recurrence-free survival. |
| Contributed Indexing: | Keywords: Cisplatin; Cytoreduction; HIPEC; Ovarian Cancer; Sodium Thiosulfate |
| Substance Nomenclature: | Q20Q21Q62J (Cisplatin) 0 (Thiosulfates) HX1032V43M (sodium thiosulfate) 0 (Antineoplastic Agents) |
| Entry Date(s): | Date Created: 20260428 Date Completed: 20260716 Latest Revision: 20260716 |
| Update Code: | 20260716 |
| DOI: | 10.7417/CT.2026.2019 |
| PMID: | 42047121 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1972-6007 |
|---|---|
| DOI: | 10.7417/CT.2026.2019 |