Academic Journal
Polyethyleneimine-based magnetic molecularly imprinted polymer for selective enrichment and highly sensitive determination of gallic acid in tea.
| Τίτλος: | Polyethyleneimine-based magnetic molecularly imprinted polymer for selective enrichment and highly sensitive determination of gallic acid in tea. |
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| Συγγραφείς: | Tang X; Department of Analytical Chemistry, China Pharmaceutical University, Nanjing 210009, China., Dube WDG; Department of Analytical Chemistry, China Pharmaceutical University, Nanjing 210009, China., Machoko WT; Department of Analytical Chemistry, China Pharmaceutical University, Nanjing 210009, China., Wang Y; Department of Analytical Chemistry, China Pharmaceutical University, Nanjing 210009, China., Wang D; Department of Analytical Chemistry, China Pharmaceutical University, Nanjing 210009, China., Tarannum N; Department of Chemistry, Chaudhary Charan Singh University, Meerut 250005, India., Fizir M; Laboratoire de Valorisation des Substances Naturelles, Université de Khemis Miliana, Algeria., Baldé ES; Institut de Recherche et de Développement des Plantes Médicinales et Alimentaires de Guinée, Dubréka, BP 6411 Conakry, Guinea., He H; Department of Analytical Chemistry, China Pharmaceutical University, Nanjing 210009, China; Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education, 24 Tongjia Lane, Nanjing 210009, China; Key Laboratory of Biomedical Functional Materials, China Pharmaceutical University, Nanjing 210009, China., Xiao D; Department of Analytical Chemistry, China Pharmaceutical University, Nanjing 210009, China; Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education, 24 Tongjia Lane, Nanjing 210009, China; Key Laboratory of Biomedical Functional Materials, China Pharmaceutical University, Nanjing 210009, China. Electronic address: xiao49562001@163.com., Dramou P; Department of Analytical Chemistry, China Pharmaceutical University, Nanjing 210009, China; Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education, 24 Tongjia Lane, Nanjing 210009, China; Key Laboratory of Biomedical Functional Materials, China Pharmaceutical University, Nanjing 210009, China. Electronic address: pierred@cpu.edu.cn. |
| Πηγή: | Food chemistry [Food Chem] 2026 Jun 15; Vol. 514, pp. 149143. Date of Electronic Publication: 2026 Apr 04. |
| Τύπος έκδοσης: | Journal Article; Evaluation Study |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE |
| Imprint Name(s): | Publication: Barking : Elsevier Applied Science Publishers Original Publication: Barking, Eng., Applied Science Publishers. |
| Ιατρικοί όροι (MeSH): | Solid Phase Extraction*/methods , Solid Phase Extraction*/instrumentation , Molecularly Imprinted Polymers*/chemistry , Molecularly Imprinted Polymers*/chemical synthesis , Polyethyleneimine*/chemistry , Gallic Acid*/isolation & purification , Gallic Acid*/analysis , Gallic Acid*/chemistry , Tea*/chemistry, Molecular Imprinting/methods ; Magnetics/methods ; Chromatography, High Pressure Liquid/methods ; Polymers/chemistry ; Adsorption |
| Περίληψη: | A polyethyleneimine-functionalized magnetic molecularly imprinted polymer (MHNT-PEI@MIP) was developed for selective enrichment and detection of gallic acid (GA) in complex tea matrices. Halloysite nanotubes provided a low-cost, high-surface-area substrate with abundant hydroxyl groups for polyethyleneimine (PEI) grafting, creating amine-rich active sites. Surface molecular imprinting with 4-vinylpyridine produced GA-specific recognition cavities. Comprehensive characterization confirmed a uniform core-shell structure, mesoporous features, and superparamagnetic behavior. Coupled with magnetic solid-phase extraction (MSPE) and HPLC, the method enabledpreconcentration of GA, achieving a limit of detection of 0.21 μg mL-1, a limit of quantification of 0.65 μg mL-1, recoveries of 95-103%, and high reproducibility. MHNT-PEI@MIP exhibited high adsorption capacity (139.7 mg g-1), pseudo-second-order kinetics, Langmuir-type isotherm behavior, and an imprinting factor of 4.12, demonstrating selectivity over structural analogues. This work provides a durable, low-cost technique integrating strong molecular recognition, high adsorption, and magnetic separability for efficient polyphenol analysis in complex food systems. (Copyright © 2026 Elsevier Ltd. All rights reserved.) |
| Competing Interests: | Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| Contributed Indexing: | Keywords: Gallic acid determination; Halloysite nanotubes; Magnetic solid-phase extraction (MSPE); Molecularly imprinted polymers |
| Substance Nomenclature: | 0 (Molecularly Imprinted Polymers) 9002-98-6 (Polyethyleneimine) 632XD903SP (Gallic Acid) 0 (Tea) 0 (Polymers) |
| Entry Date(s): | Date Created: 20260408 Date Completed: 20260714 Latest Revision: 20260714 |
| Update Code: | 20260715 |
| DOI: | 10.1016/j.foodchem.2026.149143 |
| PMID: | 41950704 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1873-7072 |
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| DOI: | 10.1016/j.foodchem.2026.149143 |