Academic Journal
Reference Values for Pulse Oximetry Testing in Permanent Teeth: A Systematic Review and Meta-Analysis.
| Τίτλος: | Reference Values for Pulse Oximetry Testing in Permanent Teeth: A Systematic Review and Meta-Analysis. |
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| Συγγραφείς: | Tietz L; School of Dentistry, Federal University of Rio Grande Do Sul (UFRGS), Porto Alegre, RS, Brazil., Weissheimer T; School of Dentistry, Federal University of Rio Grande Do Sul (UFRGS), Porto Alegre, RS, Brazil., Rösing CK; School of Dentistry, Federal University of Rio Grande Do Sul (UFRGS), Porto Alegre, RS, Brazil., Só MVR; School of Dentistry, Federal University of Rio Grande Do Sul (UFRGS), Porto Alegre, RS, Brazil. |
| Πηγή: | International endodontic journal [Int Endod J] 2026 Aug; Vol. 59 (8), pp. 1557-1585. Date of Electronic Publication: 2026 Apr 08. |
| Τύπος έκδοσης: | Journal Article; Systematic Review; Meta-Analysis |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8004996 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2591 (Electronic) Linking ISSN: 01432885 NLM ISO Abbreviation: Int Endod J Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Oxford, Blackwell Scientific Publications. |
| Ιατρικοί όροι (MeSH): | Dental Pulp*/metabolism , Dentition, Permanent* , Oximetry*, Humans ; Oxygen ; Oxygen Saturation ; Reference Values |
| Περίληψη: | Background: Pulse oximetry is an accurate diagnostic method for assessing the condition of the dental pulp; however, the normal oxygen saturation levels for each tooth type are yet to be clearly defined. Objectives: This systematic review and meta-analysis aims to answer the question: What are the reference values for pulse oximetry testing in permanent teeth with healthy pulps and complete root formation? Method: The present review followed the PRISMA recommendations. Systematic searches were conducted in the Cochrane Library, Embase, PubMed, Scopus and OpenGrey electronic databases, for studies published until September 2025, without any restrictions on the year or language of publication. The following descriptors were combined in each database: 'Endodontics', 'Dental Pulp', 'Pulse Oximetry', 'Oximeter', 'Oxygen Saturation', 'Pulp Oxygen Saturation'. Only clinical studies were included. Two independent authors were responsible for study selection and data extraction. In cases of disagreement, a third author was responsible for the final decision. The risk of bias of the included studies was assessed using the ROBINS-I tool, RoB 2.0, JBI Critical Appraisal Checklist for Analytical Cross-Sectional Studies, or QUADAS-2, depending on the study design. Results: The initial screening of databases yielded 1772 studies, with 322 duplicates excluded. From the 1450 eligible papers, 55 met the inclusion criteria and were selected for full-text reading, resulting in the selection of 35 studies. Five additional studies were included from reference lists of the selected papers. Therefore, a total of 40 studies were included in the present review. Meta-analyses of the oxygen saturation values for each maxillary and mandibular tooth type were conducted using a random-effects model. A total of 3537 teeth from twenty studies were analysed. The highest mean random-effect measure of pulp oxygen saturation was 91.73% (95% CI, 90.33%-93.13%) in mandibular incisors, and the lowest was 86.26% (95% CI, 81.90%-90.62%) in maxillary lateral incisors. Conclusion: Based on the available evidence, reference values for pulp oxygen saturation in permanent teeth with complete root development and healthy pulps ranged from 86.26% to 91.73%. These findings support the clinical relevance of establishing preliminary reference values for pulp oximetry and highlight the need for further standardisation before routine clinical implementation. Trail Registration: This study was registered in the PROSPERO database: CRD42023437995. (© 2026 The Author(s). International Endodontic Journal published by John Wiley & Sons Ltd on behalf of British Endodontic Society.) |
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| Contributed Indexing: | Keywords: dental pulp; diagnosis; endodontics; meta‐analysis; oxygen saturation; pulse oximetry |
| Substance Nomenclature: | S88TT14065 (Oxygen) |
| Entry Date(s): | Date Created: 20260408 Date Completed: 20260716 Latest Revision: 20261013 |
| Update Code: | 20261014 |
| PubMed Central ID: | PMC13373073 |
| DOI: | 10.1111/iej.70156 |
| PMID: | 41947706 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1365-2591 |
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| DOI: | 10.1111/iej.70156 |