Academic Journal
Di-His-Cu(II)-NTA spin labels for probing protein dynamics: Support from a combined crystallographic/EPR study.
| Τίτλος: | Di-His-Cu(II)-NTA spin labels for probing protein dynamics: Support from a combined crystallographic/EPR study. |
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| Συγγραφείς: | Ferraro G; Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte Sant'Angelo, via Cintia, 80126 Naples, Italy., Garribba E; Dipartimento di Medicina, Chirurgia e Farmacia, Università di Sassari, Viale San Pietro, 07100 Sassari, Italy., Merlino A; Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte Sant'Angelo, via Cintia, 80126 Naples, Italy. Electronic address: antonello.merlino@unina.it. |
| Πηγή: | Structure (London, England : 1993) [Structure] 2026 Apr 02; Vol. 34 (4), pp. 547-549. |
| Τύπος έκδοσης: | Journal Article; Comment |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2000- : Cambridge, Mass. : Cell Press Original Publication: London : Current Biology, c1993- |
| Ιατρικοί όροι (MeSH): | Muramidase*/chemistry , Muramidase*/metabolism , Copper*/chemistry , Histidine*/chemistry , Nitrilotriacetic Acid*/chemistry , Spin Labels*, Electron Spin Resonance Spectroscopy/methods ; Bacteriophage T4/enzymology ; Binding Sites ; Protein Conformation ; Crystallography, X-Ray ; Models, Molecular |
| Περίληψη: | In this issue of Structure, Besaw et al.1 report a well-designed study combining electron paramagnetic resonance measurements and structural analyses of di-histidine-Cu(II)-nitrilotriacetate binding sites in T4 lysozyme. The gained insights could have broad implications for the use of double electron-electron resonance spectroscopy in the elucidation of subtle protein conformational variations. (Copyright © 2026 Elsevier Inc. All rights reserved.) |
| Competing Interests: | Declaration of interests The authors declare no competing interests. |
| Substance Nomenclature: | EC 3.2.1.17 (Muramidase) 0 (Spin Labels) 789U1901C5 (Copper) 4QD397987E (Histidine) KA90006V9D (Nitrilotriacetic Acid) |
| Entry Date(s): | Date Created: 20260403 Date Completed: 20260714 Latest Revision: 20260714 |
| Update Code: | 20260714 |
| DOI: | 10.1016/j.str.2026.02.016 |
| PMID: | 41932316 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1878-4186 |
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| DOI: | 10.1016/j.str.2026.02.016 |