Academic Journal
Exploring Demographic Differences in Postintubation Analgesia by Racial Group, Sex, and Age.
| Τίτλος: | Exploring Demographic Differences in Postintubation Analgesia by Racial Group, Sex, and Age. |
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| Συγγραφείς: | AuBuchon KE; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia. Electronic address: kea87@georgetown.edu., Amaru A; School of Medicine, Georgetown University, Washington, District of Columbia., Cepero TQ; School of Medicine, Georgetown University, Washington, District of Columbia., Creed S; School of Medicine, Georgetown University, Washington, District of Columbia., Caputo J; School of Medicine, Georgetown University, Washington, District of Columbia., Cogan A; School of Medicine, Georgetown University, Washington, District of Columbia., Verwiel C; School of Medicine, Georgetown University, Washington, District of Columbia., Kim V; School of Medicine, Georgetown University, Washington, District of Columbia., Zhang R; Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University, Washington, District of Columbia., Ahn J; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia; Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University, Washington, District of Columbia., Arem H; MedStar Health Research Institute, Washington, District of Columbia., McCabe P; MedStar Washington Hospital Center, Washington, District of Columbia., Goyal M; School of Medicine, Georgetown University, Washington, District of Columbia; MedStar Washington Hospital Center, Washington, District of Columbia. |
| Πηγή: | The Journal of emergency medicine [J Emerg Med] 2026 May; Vol. 84, pp. 69-81. Date of Electronic Publication: 2025 Nov 26. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Country of Publication: United States NLM ID: 8412174 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0736-4679 (Print) Linking ISSN: 07364679 NLM ISO Abbreviation: J Emerg Med Subsets: MEDLINE |
| Imprint Name(s): | Publication: <2010>- : New York : Elsevier Original Publication: New York : Pergamon Press, c1983- |
| Ιατρικοί όροι (MeSH): | Analgesia*/methods , Analgesia*/statistics & numerical data , Analgesia*/standards , Demography*/statistics & numerical data , Demography*/methods , Intubation, Intratracheal*/methods , Intubation, Intratracheal*/adverse effects , Pain Management*/methods , Pain Management*/statistics & numerical data , Pain Management*/standards , Racial Groups*/statistics & numerical data , Racial Groups*/ethnology, Analgesics, Opioid/therapeutic use ; Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Age Factors ; Retrospective Studies ; Sex Factors ; White ; Black or African American |
| Περίληψη: | Background: After rapid sequence intubation (post-RSI), patients require analgesia to ensure adequate pain management; however, extant research suggests that in other medical procedures, there are demographic differences in analgesic prescribing. Objectives: We examined potential sociodemographic differences in post-RSI opioid prescribing across a Med-Atlantic healthcare system. We hypothesized that Black (vs. White), female (vs. male), and older (vs. younger) patients would receive lower opioid doses post-RSI. Methods: We conducted a retrospective chart review of all intubated adults (analytic n = 1211; 65.81% Black; 46.05% Female; Age Median = 61.00 [60.00, 63.00]) in 2019. We extracted demographics (sex, racial group, age), comorbidities, and opioid dose in Milligram Morphine Equivalent (MME). As only 29.4% of patients received an opioid, we tested our hypotheses with a zero-inflated Poisson model. Results: Increasing age was associated with a significantly lower likelihood of receiving an opioid (odds ratios [OR] = 0.81, p = 0.021) and lower MME doses when they received an opioid (rate ratio [RR] = 0.87, p < 0.001). Black (vs. White) patients had significantly higher odds of receiving an opioid (OR = 1.66, p = 0.010), but lower MME doses (RR = 0.71, p < 0.001). Sex did not significantly influence opioid prescribing likelihood, but if they received an opioid, female patients received lower MME than male patients (RR = 0.90, p = 0.018). Conclusion: Our data revealed significant racialized, sex-, and age-based disparities and inequities in opioid prescribing postintubation. Future work is needed to examine best practices in age-related post-RSI opioid recommendations and establish standardized practices that promote equitable analgesia for all patients. (Copyright © 2025 The Author(s). Published by Elsevier Inc. All rights reserved.) |
| Competing Interests: | Declaration of competing interest KA was supported by NCI T32 Grant# T32CA261787. Other authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this article. All authors contributed to the manuscript’s drafting. |
| Grant Information: | T32 CA261787 United States CA NCI NIH HHS |
| Contributed Indexing: | Keywords: opioid disparities; postintubation analgesia; postintubation sedation; rapid-sequence intubation |
| Substance Nomenclature: | 0 (Analgesics, Opioid) |
| Entry Date(s): | Date Created: 20260403 Date Completed: 20260714 Latest Revision: 20260715 |
| Update Code: | 20260716 |
| PubMed Central ID: | PMC13081784 |
| DOI: | 10.1016/j.jemermed.2025.11.007 |
| PMID: | 41932269 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 0736-4679 |
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| DOI: | 10.1016/j.jemermed.2025.11.007 |