Academic Journal
Whole Blood Viscosity Is a Predictor of Sac Shrinkage after Endovascular Aneurysm Repair.
| Τίτλος: | Whole Blood Viscosity Is a Predictor of Sac Shrinkage after Endovascular Aneurysm Repair. |
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| Συγγραφείς: | Yoshino S; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Morisaki K; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. Electronic address: morisaki.koichi.533@m.kyushu-u.ac.jp., Ito D; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Nakanishi M; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Fujioka Y; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Ueno K; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Kinoshita G; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Inoue K; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Yoshizumi T; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. |
| Πηγή: | Journal of vascular and interventional radiology : JVIR [J Vasc Interv Radiol] 2026 Jul; Vol. 37 (7), pp. 108759. Date of Electronic Publication: 2026 Mar 25. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Society of Cardiovascular and Interventional Radiology Country of Publication: United States NLM ID: 9203369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-7732 (Electronic) Linking ISSN: 10510443 NLM ISO Abbreviation: J Vasc Interv Radiol Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Reston, Va. : Society of Cardiovascular and Interventional Radiology, c1990- |
| Ιατρικοί όροι (MeSH): | Endovascular Aneurysm Repair*/adverse effects , Endovascular Aneurysm Repair*/mortality , Endoleak*/etiology , Endoleak*/therapy , Endoleak*/diagnostic imaging , Endoleak*/blood , Aortic Aneurysm, Abdominal*/surgery , Aortic Aneurysm, Abdominal*/diagnostic imaging , Aortic Aneurysm, Abdominal*/blood , Aortic Aneurysm, Abdominal*/mortality , Blood Vessel Prosthesis Implantation*/adverse effects , Blood Vessel Prosthesis Implantation*/mortality , Endovascular Procedures*/adverse effects , Blood Viscosity*, Humans ; Retrospective Studies ; Female ; Time Factors ; Risk Factors ; Male ; Aged ; Treatment Outcome ; Risk Assessment ; Predictive Value of Tests ; Aged, 80 and over |
| Περίληψη: | Purpose: To elucidate the influence of whole blood viscosity (WBV) on sac shrinkage as well as Type 2 endoleaks (T2ELs), reinterventions, and prognosis after endovascular aneurysm repair (EVAR). Materials and Methods: This was a single-center retrospective cohort study. Patients who underwent elective index EVAR between 2007 and 2022 and had postoperative follow-up of ≥1 year were reviewed. WBV was estimated using de Simone formula. The primary endpoint was sac shrinkage (≥5 mm decrease) after EVAR, and the secondary endpoints were the incidence of T2EL, reinterventions for sac expansion, and overall survival. Using receiver operating characteristics analysis, a cutoff value of WBV for sac shrinkage was determined. Results: Of 286 patients, sac shrinkage occurred in 154 (53.8%). Multivariate analysis revealed that WBV level, absence of hostile neck anatomy, and presence of circumferential thrombus were predictors of sac shrinkage. The cutoff value of WBV for sac shrinkage was 44.0 cP. The study cohort was divided into 2 groups: a high-WBV group (WBV ≥ 44.0 cP) and a low-WBV group (WBV < 44.0 cP). The high-WBV group showed a higher sac shrinkage rate (P < .001), lower incidence of T2EL (P = .021), fewer reintervention for sac expansion (P = .038), and higher overall survival (P = .023) than the low-WBV group. Conclusions: WBV is a positive predictor of sac shrinkage, and elevated WBV is associated with durable success, including a low incidence of T2EL and reintervention for sac expansion after EVAR, without a detrimental effect on prognosis. (Copyright © 2026 SIR. Published by Elsevier Inc. All rights reserved.) |
| Entry Date(s): | Date Created: 20260327 Date Completed: 20260624 Latest Revision: 20260922 |
| Update Code: | 20260923 |
| DOI: | 10.1016/j.jvir.2026.108759 |
| PMID: | 41895655 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1535-7732 |
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| DOI: | 10.1016/j.jvir.2026.108759 |