Academic Journal
Protocol for identifying and comparing neuronal ensembles using different algorithms within a graphical user interface.
| Τίτλος: | Protocol for identifying and comparing neuronal ensembles using different algorithms within a graphical user interface. |
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| Συγγραφείς: | Velazquez-Contreras R; Neurobiology Institute, UNAM, Juriquilla, Querétaro 76230, México. Electronic address: rivelco@comunidad.unam.mx., Carrillo-Reid L; Neurobiology Institute, UNAM, Juriquilla, Querétaro 76230, México. Electronic address: carrillo.reid@comunidad.unam.mx. |
| Πηγή: | STAR protocols [STAR Protoc] 2026 Jun 19; Vol. 7 (2), pp. 104443. Date of Electronic Publication: 2026 Mar 23. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Cell Press Country of Publication: United States NLM ID: 101769501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-1667 (Electronic) Linking ISSN: 26661667 NLM ISO Abbreviation: STAR Protoc Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: [Cambridge, MA] : Cell Press, [2020]- |
| Ιατρικοί όροι (MeSH): | Neurons*/physiology , Neurons*/cytology , Algorithms* , User-Computer Interface*, Microscopy, Fluorescence, Multiphoton/methods ; Animals ; Software |
| Περίληψη: | Neuronal ensembles are groups of neurons with coordinated activity that are related to a specific brain function. Here, we present a protocol to identify and compare neuronal ensembles from neuronal activity data obtained through two-photon microscopy or electrophysiological recordings using a unified graphical user interface (Ensembles Comparison and Recognition [ENCORE]). We describe steps for installing ENCORE, data loading, neuronal ensemble identification, inspecting results, and comparison of five different algorithms. We then detail procedures for evaluating functional relevance of identified neuronal ensembles. For complete details on the use and execution of this protocol, please refer to Carrillo-Reid.1. (Copyright © 2026 The Author(s). Published by Elsevier Inc. All rights reserved.) |
| Competing Interests: | Declaration of interests The authors declare no competing interests. |
| References: | Nat Commun. 2024 Apr 12;15(1):3192. (PMID: 38609354) J Neurosci Methods. 2013 Nov 15;220(2):149-66. (PMID: 23639919) PLoS One. 2021 Jul 30;16(7):e0251647. (PMID: 34329314) J Neurosci. 2015 Jun 10;35(23):8813-28. (PMID: 26063915) Curr Biol. 2017 Aug 21;27(16):2407-2419.e4. (PMID: 28781054) |
| Contributed Indexing: | Keywords: Behavior; Computer sciences; Neuroscience |
| Entry Date(s): | Date Created: 20260325 Date Completed: 20260623 Latest Revision: 20260813 |
| Update Code: | 20260813 |
| PubMed Central ID: | PMC13045672 |
| DOI: | 10.1016/j.xpro.2026.104443 |
| PMID: | 41880329 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 2666-1667 |
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| DOI: | 10.1016/j.xpro.2026.104443 |