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Pharmacology of Vitamin E.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Pharmacology of Vitamin E.
Συγγραφείς: Traber MG; Linus Pauling Institute, Oregon State University, Corvallis, Oregon, USA.; College of Health, Oregon State University, Corvallis, Oregon, USA.
Πηγή: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2026 Apr; Vol. 138 (4), pp. e70225.
Τύπος έκδοσης: Journal Article; Review
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print Cited Medium: Internet ISSN: 1742-7843 (Electronic) Linking ISSN: 17427835 NLM ISO Abbreviation: Basic Clin Pharmacol Toxicol Subsets: MEDLINE
Imprint Name(s): Publication: <2005-> : Oxford : Blackwell
Original Publication: Copenhagen, Denmark : Oxford, UK : Nordic Pharmacological Society Distributed by Blackwell Munksgaard, 2004-
Ιατρικοί όροι (MeSH): alpha-Tocopherol*/pharmacokinetics , alpha-Tocopherol*/pharmacology , alpha-Tocopherol*/metabolism , Vitamin E*/pharmacology , Vitamin E*/pharmacokinetics , Vitamin E*/metabolism, Humans ; Animals
Περίληψη: The mechanisms for the preferential α-tocopherol retention in the human body fall under the usual pharmacologic categories of absorption, disposition, metabolism and catabolism and excretion (ADME). Kinetic studies using α-tocopherol labelled with either radioactive or stable isotopes have been instrumental in our understanding of vitamin E trafficking and status. Additionally, different types of mathematical modelling have yielded novel information. Therefore, I will address each of these topics, what is currently known and not known, emphasizing what has been recently discovered and how the various mechanisms impact clinical disorders.
(© 2026 Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society). Published by John Wiley & Sons Ltd.)
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Contributed Indexing: Keywords: absorption; alpha‐tocopherol; distribution; excretion; metabolism; tocochromanols
Substance Nomenclature: H4N855PNZ1 (alpha-Tocopherol)
1406-18-4 (Vitamin E)
Entry Date(s): Date Created: 20260319 Date Completed: 20260711 Latest Revision: 20260711
Update Code: 20260711
DOI: 10.1111/bcpt.70225
PMID: 41854488
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1742-7843
DOI:10.1111/bcpt.70225