Academic Journal
Cognitive Rehabilitation After Stroke: A Case Series Testing a New Method to Transfer Gains to Daily Life.
| Title: | Cognitive Rehabilitation After Stroke: A Case Series Testing a New Method to Transfer Gains to Daily Life. |
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| Authors: | Uswatte G; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Physical Therapy, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Taub E; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., McKay S; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Mitchell BS; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Neurology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Blake JA; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Knight A; Department of Neurology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Biney F; Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Iosipchuk O; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Mark VW; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Neurology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Lin C; Department of Neurology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Birmingham Veterans Affairs Medical Center, Birmingham, AL, USA., Zhou X; Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Ball K; Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Ophthalmology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Neurobiology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA. |
| Source: | Restorative neurology and neuroscience [Restor Neurol Neurosci] 2026 Aug; Vol. 44 (3), pp. 360-373. Date of Electronic Publication: 2026 Mar 17. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: IOS Press Country of Publication: United States NLM ID: 9005499 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3627 (Electronic) Linking ISSN: 09226028 NLM ISO Abbreviation: Restor Neurol Neurosci Subsets: MEDLINE |
| Imprint Name(s): | Publication: Amsterdam : IOS Press Original Publication: Amsterdam : Elsevier Science Publishers BV, c1989- |
| MeSH Terms: | Activities of Daily Living*/psychology , Stroke Rehabilitation*/methods , Stroke*/complications , Stroke*/psychology , Cognitive Dysfunction*/rehabilitation , Cognitive Dysfunction*/etiology , Transfer, Psychology*/physiology , Cognition Disorders*/rehabilitation , Cognition Disorders*/etiology , Cognitive Behavioral Therapy*/methods, Constraint Induced Movement Therapy/methods ; Humans ; Female ; Male ; Cognitive Training ; Aged ; Middle Aged ; Neuropsychological Tests ; Processing Speed ; Pilot Projects ; Treatment Outcome |
| Abstract: | This case-series piloted a novel cognitive rehabilitation approach, i.e., Constraint-Induced Cognitive Therapy (CICT), for improving Instrumental Activities of Daily Living (IADL) in stroke survivors with chronic, mild-to-moderate, cognitive impairment. Four consecutively sampled stroke survivors (mean chronicity=18 months, SD = 10) with mild (n = 3) or moderate (n = 1) cognitive impairment received 35 h of CICT. CICT combined two empirically supported approaches: Speed of Processing Training (SOPT) and behavior change techniques from Constraint-Induced Movement Therapy (CIMT) adapted to transfer gains from in-lab cognitive training to daily life. The latter featured IADL training following shaping principles and a suite of behavioral techniques, called the Transfer Package, to promote participation in cognitively-based functional activities outside of the lab. Outcome measures assessed cognitive processing speed (Useful Field of View, UFOV) and IADL performance outside the treatment setting (Canadian Occupational Performance Measure, COPM). All three participants with valid UFOV data displayed meaningful improvements after treatment in cognitive processing speed (M = 64%, SD = 40, d'=1.6). All three with COPM data reported meaningful improvements in satisfaction with IADL performance (M = 2.87, SD = 1.5, d'=1.9). Values of d' ≥ 0.57 are large. Per structured interviews developed for this study, the IADL improvements present after treatment lasted for at least a year. These promising findings warrant further study. |
| Competing Interests: | Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article, except for Karlene Ball, whose disclosure is below. |
| Contributed Indexing: | Keywords: IADL; cognitive dysfunction; cognitive training; functional status; processing speed |
| Entry Date(s): | Date Created: 20260317 Date Completed: 20260723 Latest Revision: 20260723 |
| Update Code: | 20260723 |
| DOI: | 10.1177/09226028261418261 |
| PMID: | 41841502 |
| Database: | MEDLINE |
| ISSN: | 1878-3627 |
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| DOI: | 10.1177/09226028261418261 |