Academic Journal
Medication Adherence and Its Determinants Among Adults With Heart Failure: A Study in Selected Hospitals of North Shewa Zone, Oromia, Ethiopia (2024)-A Multicenter Institutional-Based Cross-Sectional Study.
| Title: | Medication Adherence and Its Determinants Among Adults With Heart Failure: A Study in Selected Hospitals of North Shewa Zone, Oromia, Ethiopia (2024)-A Multicenter Institutional-Based Cross-Sectional Study. |
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| Authors: | Mohammed AS; Department of Public Health, Kidus Petros Specialized Hospital, Addis Ababa, Ethiopia., Kemal WS; Department of Advanced Adult Health Nursing, Ras Desta Damtew Memory Hospital, Addis Ababa, Ethiopia., Kolbay AS; Department of Advanced Adult Health Nursing, Kidus Petros Specialized Hospital, Addis Ababa, Ethiopia., Yesuf MH; Department of Internal Medicine, Kidus Petros Specialized Hospital, Addis Ababa, Ethiopia., Abebe SS; Department of Internal Medicine, Kidus Petros Specialized Hospital, Addis Ababa, Ethiopia., Solomon B; Department of Clinical Trials, Kidus Petros Specialized Hospital, Addis Ababa, Ethiopia., Deress GM; Department of Anesthesia, College of Health Sciences, School of Medicine, Debre Tabor University, Ethiopia. |
| Source: | Advances in rehabilitation science and practice [Adv Rehabil Sci Pract] 2026 Mar 10; Vol. 15, pp. 27536351251391632. Date of Electronic Publication: 2026 Mar 10 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: SAGE Publications Country of Publication: England NLM ID: 9918540788406676 Publication Model: eCollection Cited Medium: Internet ISSN: 2753-6351 (Electronic) Linking ISSN: 27536351 NLM ISO Abbreviation: Adv Rehabil Sci Pract Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: [London] : SAGE Publications, [2023]- |
| Abstract: | Background: Effective management of heart failure (HF) critically relies on adherence to evidence-based pharmacotherapy. However, adherence remains suboptimal, contributing to preventable hospital readmissions, disease progression, and increased healthcare costs. This study assessed medication adherence and associated factors among adult HF patients in selected hospitals of North Shewa Zone, Oromia, Ethiopia. Methods: An institutional-based cross-sectional study was conducted among 327 adult HF patients selected via simple random sampling. The sample size was calculated using a single population proportion formula (P = .738, 95% confidence interval [CI], 5% margin of error) and adjusted for a 10% non-response rate. Medication adherence was measured using the Amharic version of the Morisky Medication Adherence Scale (MMAS-8). Data were entered and analyzed using SPSS version 26. Logistic regression identified factors associated with adherence, with statistical significance set at P < .05. Results: Out of 327 participants, 165 (50.5%) were female, with a mean age of 43 ± 17.6 years. Good medication adherence was observed in 146 participants (44.65%). Independent predictors of adherence included higher HF knowledge (AOR = 2.03; 95% CI = 1.13-3.66; P = .018), access to free medications (AOR = 1.78; 95% CI = 1.04-3.03; P = .034), and receiving education on medication adherence (AOR = 2.20; 95% CI = 1.22-3.97; P = .009). Conclusion and Recommendations: Less than half of HF patients demonstrated good medication adherence. Structured patient education, reliable access to medications, and improved HF knowledge were key determinants of adherence. Interventions targeting these factors are strongly recommended to enhance medication adherence and improve clinical outcomes among HF patients in North Shewa Zone. (© The Author(s) 2026.) |
| Competing Interests: | The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. |
| References: | Eur J Heart Fail. 2003 Jun;5(3):363-70. (PMID: 12798836) J Clin Hypertens (Greenwich). 2008 May;10(5):348-54. (PMID: 18453793) Am Heart J. 2009 Oct;158(4):644-52. (PMID: 19781426) |
| Contributed Indexing: | Keywords: Ethiopia; North Shewa Zone; Oromia; associated factors; determinants; heart failure; medication adherence |
| Entry Date(s): | Date Created: 20260313 Date Completed: 20260313 Latest Revision: 20260813 |
| Update Code: | 20260813 |
| PubMed Central ID: | PMC12976411 |
| DOI: | 10.1177/27536351251391632 |
| PMID: | 41822314 |
| Database: | MEDLINE |
| ISSN: | 2753-6351 |
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| DOI: | 10.1177/27536351251391632 |