Caries in primary teeth and caries in permanent teeth: association and effect modifiers.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Caries in primary teeth and caries in permanent teeth: association and effect modifiers.
Συγγραφείς: Wu S; Applied Oral Sciences and Community Dental Care, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China., Lo ECM; Applied Oral Sciences and Community Dental Care, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China., Chu CH; Restorative Dental Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China., Wong MCM; Applied Oral Sciences and Community Dental Care, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China. Electronic address: mcmwong@hku.hk.
Πηγή: International dental journal [Int Dent J] 2026 Jun; Vol. 76 (3), pp. 109462. Date of Electronic Publication: 2026 Feb 27.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: England NLM ID: 0374714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-595X (Electronic) Linking ISSN: 00206539 NLM ISO Abbreviation: Int Dent J Subsets: MEDLINE
Imprint Name(s): Publication: 2021- : London : Elsevier
Original Publication: London : FDI World Dental
Ιατρικοί όροι (MeSH): Dental Caries*/epidemiology , Tooth, Deciduous* , Dentition, Permanent*, Hong Kong/epidemiology ; Humans ; Male ; Child ; Retrospective Studies ; Female ; DMF Index ; Incidence ; Risk Factors
Περίληψη: Objectives: To investigate the relationship between caries in primary teeth and caries in permanent teeth among primary school students, and to identify potential effect modifiers of this relationship.
Methods: This retrospective cohort study utilized real-world caries examination data from the School Dental Care Service (SDCS) provided by the Hong Kong SAR government. Primary school students in grades 3 (P3) or 4 (P4) who participated in the SDCS were recruited from school dental clinics. The exposure was defined as any caries experience in primary teeth in Grade 1. To account for potential confounding factors, the marginal structural model with overlap weight was applied to estimate the average treatment effect for the overlap population.
Results: Among 825 children (mean [SD] age in P1: 6.2 [0.3]; boys 54.7%) without caries in permanent teeth (DMFT = 0) in P1, the incidence of caries experience in permanent teeth (DMFT > 0) increased to 5.7% and 10.5% in P2 and P3, respectively. Among those with caries experience in primary teeth (dmft > 0, n = 443), 15.4% had caries experience in permanent teeth in P3 compared to only 4.9% among those without (n = 382; adjusted risk ratio 2.8 [95% CI: 1.7-4.8; P < .001]; adjusted risk difference 9.6% [95% CI: 5.4-13.8; P < .001]). Sex and only-child status significantly modified this relationship, with stronger associations observed in boys and non-only children.
Conclusions: Caries in primary teeth increased the risk of developing caries in permanent teeth. This association was modified by sex and only-child status.
Clinical Significance: Controlling caries in primary teeth is essential for preventing caries in permanent teeth. Risk-stratified interventions targeting boys and non-only children may optimize preventive outcomes and resource allocation in oral health promotion programs.
(Copyright © 2026 The Authors. Published by Elsevier Inc. All rights reserved.)
Competing Interests: Conflict of interest None disclosed.
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Contributed Indexing: Keywords: Caries; Causal inference; Dental public health; Early childhood caries; Electronic dental records; Preventive dentistry
Entry Date(s): Date Created: 20260228 Date Completed: 20260709 Latest Revision: 20260813
Update Code: 20260813
PubMed Central ID: PMC12962149
DOI: 10.1016/j.identj.2026.109462
PMID: 41762791
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1875-595X
DOI:10.1016/j.identj.2026.109462