Academic Journal
Safety Assessment of Salvia officinalis (Sage)-Derived Ingredients as Used in Cosmetics.
| Τίτλος: | Safety Assessment of Salvia officinalis (Sage)-Derived Ingredients as Used in Cosmetics. |
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| Συγγραφείς: | Raj PS; Cosmetic Ingredient Review Former Senior Scientific Analyst/Writer., Bergfeld WF; Expert Panel for Cosmetic Ingredient Safety Member., Belsito DV; Expert Panel for Cosmetic Ingredient Safety Member., Cohen DE; Expert Panel for Cosmetic Ingredient Safety Member., Klaassen CD; Expert Panel for Cosmetic Ingredient Safety Member., Liebler DC; Expert Panel for Cosmetic Ingredient Safety Former Member., Peterson LA; Expert Panel for Cosmetic Ingredient Safety Former Member., Rettie AE; Expert Panel for Cosmetic Ingredient Safety Member., Ross D; Expert Panel for Cosmetic Ingredient Safety Member., Shank RC; Expert Panel for Cosmetic Ingredient Safety Former Member., Slaga TJ; Expert Panel for Cosmetic Ingredient Safety Former Member., Snyder PW; Expert Panel for Cosmetic Ingredient Safety Member., Tilton SC; Expert Panel for Cosmetic Ingredient Safety Member., Fiume MM; Cosmetic Ingredient Review Senior Director., Heldreth B; Cosmetic Ingredient Review Executive Director. |
| Πηγή: | International journal of toxicology [Int J Toxicol] 2026 Feb; Vol. 45 (1_suppl), pp. 88S-105S. Date of Electronic Publication: 2026 Feb 28. |
| Τύπος έκδοσης: | Journal Article; Review |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Sage Publications Country of Publication: United States NLM ID: 9708436 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1092-874X (Electronic) Linking ISSN: 10915818 NLM ISO Abbreviation: Int J Toxicol Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2009- : Thousand Oaks, CA : Sage Publications Original Publication: Washington, DC : Taylor & Francis, c1997- |
| Ιατρικοί όροι (MeSH): | Salvia officinalis*/chemistry , Cosmetics*/chemistry , Cosmetics*/toxicity , Plant Extracts*/toxicity , Plant Extracts*/chemistry , Consumer Product Safety*, Animals ; Humans |
| Περίληψη: | The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 12 Salvia officinalis (Sage)-derived ingredients as used in cosmetic formulations. These ingredients are most commonly reported to function as skin conditioning agents and fragrance ingredients. Because final product formulations may contain multiple botanicals, each containing the same constituents of concern, formulators are advised to be aware of these constituents and to avoid reaching levels that may be hazardous to consumers. With Salvia officinalis (Sage)-derived ingredients, the Panel was concerned about certain terpenes as potential sensitizers. Industry should use current good manufacturing practices to minimize impurities. The Panel reviewed data relevant to the safety of these ingredients in cosmetic formulations, and concluded that 6 of the ingredients (those derived from the leaves and the oil) are safe in cosmetics in the present practices of use and concentrations described in this safety assessment when formulated to be non-sensitizing, and that the data are insufficient to make a determination of safety for the remaining 6 ingredients under the intended conditions of use in cosmetic formulations. |
| Competing Interests: | Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. |
| Contributed Indexing: | Keywords: Cosmetic Ingredient Review; Cosmetics; Expert Panel for Cosmetic Ingredient Safety; Safety; Salvia Officinalis (Sage) Extract; Salvia Officinalis (Sage) Flower/Leaf/Stem Extract; Salvia Officinalis (Sage) Flower/Leaf/Stem Juice; Salvia Officinalis (Sage) Flower/Leaf/Stem Water; Salvia Officinalis (Sage) Leaf; Salvia Officinalis (Sage) Leaf Extract; Salvia Officinalis (Sage) Leaf Oil; Salvia Officinalis (Sage) Leaf Powder; Salvia Officinalis (Sage) Leaf Water; Salvia Officinalis (Sage) Oil; Salvia Officinalis (Sage) Root Extract; Salvia Officinalis (Sage) Water |
| Substance Nomenclature: | 0 (Cosmetics) 0 (Plant Extracts) |
| Entry Date(s): | Date Created: 20260228 Date Completed: 20260709 Latest Revision: 20260723 |
| Update Code: | 20260723 |
| DOI: | 10.1177/10915818261425569 |
| PMID: | 41761900 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1092-874X |
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| DOI: | 10.1177/10915818261425569 |