Academic Journal
Unraveling posttranscriptional regulatory networks in phage infection.
| Title: | Unraveling posttranscriptional regulatory networks in phage infection. |
|---|---|
| Authors: | Velasco Gomariz M; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), Würzburg 97080, Germany., Hör J; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), Würzburg 97080, Germany; Institute of Molecular Infection Biology, University of Würzburg, Würzburg 97080, Germany. Electronic address: jens.hoer@helmholtz-hiri.de. |
| Source: | Trends in microbiology [Trends Microbiol] 2026 Mar; Vol. 34 (3), pp. 230-231. Date of Electronic Publication: 2026 Feb 26. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Elsevier Trends Journals Country of Publication: England NLM ID: 9310916 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4380 (Electronic) Linking ISSN: 0966842X NLM ISO Abbreviation: Trends Microbiol Subsets: MEDLINE |
| Imprint Name(s): | Publication: Cambridge : Elsevier Trends Journals Original Publication: Cambridge, UK : Elsevier Trends Journals, c1993- |
| MeSH Terms: | Bacteriophage lambda*/genetics , Bacteriophage lambda*/physiology , Gene Regulatory Networks* , Gene Expression Regulation, Viral*, Host Factor 1 Protein/genetics ; Host Factor 1 Protein/metabolism ; Regulon |
| Abstract: | Phages employ sophisticated transcriptional regulatory networks to optimize replication. Recently, Silverman et al. used RIL-seq (RNA interaction by ligation and sequencing) to reveal an additional layer of regulation and uncovered the Hfq-mediated posttranscriptional regulon of the model phage lambda. (Copyright © 2026 The Author(s). Published by Elsevier Ltd.. All rights reserved.) |
| Competing Interests: | Declaration of interests None declared. |
| Contributed Indexing: | Keywords: RIL-seq; gene regulation; phage biology; phage lambda; posttranscriptional regulation; sRNA |
| Substance Nomenclature: | 0 (Host Factor 1 Protein) |
| Entry Date(s): | Date Created: 20260227 Date Completed: 20260710 Latest Revision: 20260710 |
| Update Code: | 20260711 |
| DOI: | 10.1016/j.tim.2026.01.003 |
| PMID: | 41760429 |
| Database: | MEDLINE |
| ISSN: | 1878-4380 |
|---|---|
| DOI: | 10.1016/j.tim.2026.01.003 |