Academic Journal
Dynamic Modulation of Beta-Band Oscillations in the LGN and Their Role in Visual Processing.
| Τίτλος: | Dynamic Modulation of Beta-Band Oscillations in the LGN and Their Role in Visual Processing. |
|---|---|
| Συγγραφείς: | Alitto HJ; Center for Neuroscience, University of California, Davis, Davis, California 95618 hjalitto@ucdavis.edu.; Department of Neurobiology, Physiology, and Behavior, University of California, Davis, Davis, California 95618., Sanchez AN; Center for Neuroscience, University of California, Davis, Davis, California 95618.; Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, California 94720.; Department of Neuroscience, University of California, Berkeley, Berkeley, California 94720., Alexander PC; Center for Neuroscience, University of California, Davis, Davis, California 95618.; Information Systems and Modeling Group (A-1), Los Alamos National Laboratory, Los Alamos, New Mexico 87545., Usrey WM; Center for Neuroscience, University of California, Davis, Davis, California 95618.; Department of Neurobiology, Physiology, and Behavior, University of California, Davis, Davis, California 95618. |
| Πηγή: | The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2026 Mar 18; Vol. 46 (11). Date of Electronic Publication: 2026 Mar 18. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE |
| Imprint Name(s): | Publication: Washington, DC : Society for Neuroscience Original Publication: [Baltimore, Md.] : The Society, c1981- |
| Ιατρικοί όροι (MeSH): | Geniculate Bodies*/physiology , Beta Rhythm*/physiology , Visual Perception*/physiology , Primary Visual Cortex*/physiology, Visual Pathways/physiology ; Visual Cortex/physiology ; Action Potentials/physiology ; Neurons/physiology ; Animals ; Male ; Female ; Photic Stimulation ; Macaca mulatta ; Local Field Potential Measurement |
| Περίληψη: | Neuronal oscillations are a ubiquitous feature of thalamocortical networks and can be dynamically modulated across processing states, enabling thalamocortical communication to flexibly adapt to varying environmental and behavioral demands. The lateral geniculate nucleus (LGN), like all thalamic nuclei, engages in reciprocal synaptic interactions with the cortex, relaying retinal information to and receiving feedback input from primary visual cortex (V1). While retinal excitation is the primary driver of LGN activity, retinal synapses represent a minority of the total synaptic input onto LGN neurons, allowing for both retinogeniculate and geniculocortical signals to be influenced by nonretinal sources. To gain a holistic view of network processing in the geniculocortical pathway, we performed simultaneous extracellular recordings from the LGN and V1 of behaving macaque monkeys (two male, four female), measuring local field potentials (LFPs) and spiking activity. These recordings revealed prominent beta-band oscillations coherent between the LGN and V1 that influenced spike timing in the LGN and were statistically consistent with a feedforward process from the LGN to V1. These thalamocortical oscillations were suppressed by visual stimulation, spatial attention, and behavioral arousal, strongly suggesting that these oscillations are not a feature of active visual processing. Instead, they appear analogous to occipital lobe, alpha oscillations recorded in humans and may represent a signature of signal suppression that occurs during periods of low engagement or active distractor suppression. (Copyright © 2026 the authors.) |
| Competing Interests: | The authors declare no competing financial interests. |
| Σχόλια: | Update of: bioRxiv. 2025 Jul 13:2025.07.08.663741. doi: 10.1101/2025.07.08.663741.. (PMID: 40672230) |
| Grant Information: | R01 EY036242 United States EY NEI NIH HHS; P50 MH132642 United States MH NIMH NIH HHS |
| Contributed Indexing: | Keywords: arousal; contrast gain control; cortex; spatial attention; thalamus |
| Entry Date(s): | Date Created: 20260217 Date Completed: 20260708 Latest Revision: 20260708 |
| Update Code: | 20260708 |
| PubMed Central ID: | PMC13000994 |
| DOI: | 10.1523/JNEUROSCI.1342-25.2026 |
| PMID: | 41702717 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1529-2401 |
|---|---|
| DOI: | 10.1523/JNEUROSCI.1342-25.2026 |