Academic Journal
Harmonized Protocol for Subfield Segmentation in the Hippocampal Body on High-Resolution In Vivo MRI From the Hippocampal Subfields Group (HSG).
| Title: | Harmonized Protocol for Subfield Segmentation in the Hippocampal Body on High-Resolution In Vivo MRI From the Hippocampal Subfields Group (HSG). |
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| Authors: | Daugherty AM; Wayne State University, Detroit, Michigan, USA., Carr V; San Jose State University, San Jose, California, USA., Canada KL; University of Massachusetts Amherst, Amherst, Massachusetts, USA., Rådman G; Lund University, Lund, Sweden., Brown T; Georgia Institute of Technology, Atlanta, Georgia, USA., Augustinack J; Massachusetts General Hospital, Harvard, Massachusetts, USA., Amunts K; Research Centre Jülich, Institute of Neurosciences and Medicine (INM-1), Jülich, Germany.; C. & O. Vogt Institute for Brain Research, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany., Bakker A; Johns Hopkins University, Baltimore, Maryland, USA., Berron D; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany., Burggren A; University of Oregon, Eugene, Oregon, USA., Chetelat G; Normandie Univ, UNICAEN, INSERM, U1237, PhIND, Neuropresage Team, Caen, France., de Flores R; Normandie Univ, UNICAEN, INSERM, U1237, PhIND, Neuropresage Team, Caen, France., Ding SL; Allen Institute for Brain Science, Seatle, Washington, USA., Huang Y; University of Alberta, Edmonton, Alberta, Canada., Johnson E; University of California Davis, Davis, California, USA., Kanel P; University of Michigan, Ann Arbor, Michigan, USA., Keresztes A; Brain Imaging Centre, HUN-REN Research Centre for Natural Sciences, and Institute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary., Kedo O; Research Centre Jülich, Institute of Neurosciences and Medicine (INM-1), Jülich, Germany., Kennedy KM; Center for Vital Longevity, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Dallas, Texas, USA., Lee J; University of California Davis, Davis, California, USA., Malykhin N; University of Alberta, Edmonton, Alberta, Canada., Martinez A; San Jose State University, San Jose, California, USA., Mueller S; University of California San Francisco, San Francisco, California, USA., Mulligan E; University of Illinois at Chicago, Chicago, Illinois, USA., Ofen N; Center for Vital Longevity, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Dallas, Texas, USA., Palombo D; The University of British Columbia, Vancouver, British Columbia, Canada., Pasquini L; University of California San Francisco, San Francisco, California, USA., Pluta J; University of Pennsylvania, Philadelphia, Pennsylvania, USA., Raz N; Stony Brook University, Stony Brook, New York, USA.; Max Planck Institute for Human Development, Berlin, Germany., Riggins T; University of Maryland, College Park, Maryland, USA., Rodrigue KM; Center for Vital Longevity, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Dallas, Texas, USA., Saifullah S; Wayne State University, Detroit, Michigan, USA., Schlichting ML; University of Toronto, Toronto, Ontario, Canada., Stark C; University of California Irvine, Irvine, California, USA., Wang L; University of Toronto, Toronto, Ontario, Canada.; Baycrest Academy for Research and Education, Rotman Research Institute, Toronto, Ontario, Canada., Yushkevich P; Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., La Joie R; Memory and Aging Center, UCSF Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, California, USA., Wisse L; Lund University, Lund, Sweden., Olsen R; University of Toronto, Toronto, Ontario, Canada.; Baycrest Academy for Research and Education, Rotman Research Institute, Toronto, Ontario, Canada. |
| Corporate Authors: | Alzheimer’s Disease Neuroimaging Initiative, Hippocampal Subfields Group |
| Source: | Hippocampus [Hippocampus] 2026 Mar; Vol. 36 (2), pp. e70073. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 9108167 Publication Model: Print Cited Medium: Internet ISSN: 1098-1063 (Electronic) Linking ISSN: 10509631 NLM ISO Abbreviation: Hippocampus Subsets: MEDLINE |
| Imprint Name(s): | Publication: New York, NY : Wiley Original Publication: New York, NY : Churchill Livingstone, c1991- |
| MeSH Terms: | Magnetic Resonance Imaging*/methods , Hippocampus*/anatomy & histology , Hippocampus*/diagnostic imaging , Image Processing, Computer-Assisted*/methods, Humans ; Female ; Male ; Adult ; Middle Aged |
| Abstract: | Hippocampal subfields differentially develop and age, and they vary in vulnerability to neurodegenerative diseases. Innovation in high-resolution imaging has accelerated clinical research on human hippocampal subfields, but substantial differences in segmentation protocols impede comparisons of results across laboratories. The Hippocampal Subfields Group (HSG) is an international organization seeking to address this issue by developing a histologically valid, reliable, and freely available segmentation protocol for high-resolution T (© 2026 The Author(s). Hippocampus published by Wiley Periodicals LLC.) |
| Comments: | Update of: bioRxiv. 2025 May 04:2025.04.29.651039. doi: 10.1101/2025.04.29.651039.. (PMID: 40654693) |
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| Contributed Indexing: | Keywords: Cornu Ammonis; dentate gyrus; neuroimaging; subiculum |
| Entry Date(s): | Date Created: 20260204 Date Completed: 20260706 Latest Revision: 20260706 |
| Update Code: | 20260707 |
| PubMed Central ID: | PMC12869135 |
| DOI: | 10.1002/hipo.70073 |
| PMID: | 41635209 |
| Database: | MEDLINE |
| ISSN: | 1098-1063 |
|---|---|
| DOI: | 10.1002/hipo.70073 |