Academic Journal
Neonatal transport and therapeutic hypothermia: A focus on hypoxic-ischemic encephalopathy outcomes in a tertiary center in northern Taiwan.
| Τίτλος: | Neonatal transport and therapeutic hypothermia: A focus on hypoxic-ischemic encephalopathy outcomes in a tertiary center in northern Taiwan. |
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| Συγγραφείς: | Hsieh PY; Division of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan., Yang CY; Division of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan., Chiang CC; Division of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan., Hsu KH; Division of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan; Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Taoyuan, Taiwan., Chang HP; Division of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan; Division of Pediatric Critical Care Medicine, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan., Chu SM; Division of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan; Division of Respiratory Therapy, Chang Gung Memorial Hospital, Taoyuan, Taiwan., Chiang MC; Division of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan; Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Taoyuan, Taiwan; Division of Respiratory Therapy, Chang Gung Memorial Hospital, Taoyuan, Taiwan. Electronic address: cmc123@cgmh.org.tw. |
| Πηγή: | Pediatrics and neonatology [Pediatr Neonatol] 2026 Sep; Vol. 67 (5), pp. 497-502. Date of Electronic Publication: 2026 Jan 20. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Country of Publication: Singapore NLM ID: 101484755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-1692 (Electronic) Linking ISSN: 18759572 NLM ISO Abbreviation: Pediatr Neonatol Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: [Singapore] : Elsevier |
| Ιατρικοί όροι (MeSH): | Hypoxia-Ischemia, Brain*/therapy , Hypoxia-Ischemia, Brain*/mortality , Transportation of Patients*/statistics & numerical data , Hypothermia, Induced*, Taiwan/epidemiology ; Humans ; Retrospective Studies ; Infant, Newborn ; Female ; Tertiary Care Centers ; Male ; Treatment Outcome |
| Περίληψη: | Background: Neonatal transport is a critical component of regionalized perinatal care and it has played a significant role in improving neonatal survival. However, contemporary clinical practices of neonatal transport in Taiwan remain underreported. This study aimed to comprehensively analyze the characteristics and outcomes of neonates transported to a tertiary medical center in northern Taiwan, with particular focus on those diagnosed with hypoxic-ischemic encephalopathy (HIE) and treated with therapeutic hypothermia (TH). Methods: We retrospectively reviewed medical and transport records of neonates transported to the neonatal care center at Chang Gung Memorial Hospital, Linkou Branch, between January 2019 and December 2021. A subgroup analysis was performed comparing inborn and outborn neonates who received TH. Results: During the study period, 835 neonates were transported, accounting for 15.8 % of total admissions. Among them, 550 (66 %) were term neonates, and 39 (5 %) were very or extremely preterm. The predominant reason for transport was respiratory distress (56 %), followed by gastrointestinal (12 %) and cardiovascular (10 %) issues. Endotracheal intubation was required in 13.0 % of neonates during transport, with 44.0 % of these performed by the transport team. A total of 21 (2.5 %) died before discharge, including 14 (1.7 %) within the first week and 7 (0.8 %) within 24 h post-transport. Seventeen outborn and four inborn neonates received TH during the study period. Three outborn neonates initiated TH beyond the first 6 h. Most delays were marginal and associated with longer admission times. Notably, outborn neonates diagnosed with HIE who underwent TH had comparable short-term outcomes to the inborn group. Conclusion: Respiratory distress remained the predominant reason for neonatal transport, with over half of the cases requiring ventilator support. In neonates with hypoxic-ischemic encephalopathy, timely therapeutic hypothermia was generally achievable, and short-term outcomes were comparable to inborn counterparts. (Copyright © 2026 Taiwan Pediatric Association. Published by Elsevier B.V. All rights reserved.) |
| Competing Interests: | Conflicts of interests All authors declare no conflicts of interest. |
| Contributed Indexing: | Keywords: Hypoxic-ischemic encephalopathy; Infant; Therapeutic hypothermia; Transport of patients |
| Entry Date(s): | Date Created: 20260130 Date Completed: 20260824 Latest Revision: 20260824 |
| Update Code: | 20260825 |
| DOI: | 10.1016/j.pedneo.2025.08.015 |
| PMID: | 41617552 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 2212-1692 |
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| DOI: | 10.1016/j.pedneo.2025.08.015 |