Academic Journal
Comparison of PetMAP digital and Mindray wrist oscillometric blood pressure measurements with invasive blood pressure in anaesthetized bonobos (Pan paniscus).
| Title: | Comparison of PetMAP digital and Mindray wrist oscillometric blood pressure measurements with invasive blood pressure in anaesthetized bonobos (Pan paniscus). |
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| Authors: | Bucknell P; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Loughborough, UK; Twycross Zoo, Atherstone, UK., Hillen F; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Loughborough, UK., Dobbs P; Twycross Zoo, Atherstone, UK., Ashfield S; Twycross Zoo, Atherstone, UK., White K; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Loughborough, UK. Electronic address: Kate.white@nottingham.ac.uk. |
| Source: | Veterinary anaesthesia and analgesia [Vet Anaesth Analg] 2026 May-Jun; Vol. 53 (3), pp. 101153. Date of Electronic Publication: 2025 Nov 01. |
| Publication Type: | Journal Article; Comparative Study |
| Language: | English |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 100956422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1467-2995 (Electronic) Linking ISSN: 14672987 NLM ISO Abbreviation: Vet Anaesth Analg Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2017- : New York, NY : Elsevier Original Publication: Oxford, UK : Blackwell Science, c2000- |
| MeSH Terms: | Blood Pressure Determination*/veterinary , Blood Pressure Determination*/instrumentation , Blood Pressure Determination*/methods , Pan paniscus*/physiology , Blood Pressure*/physiology , Anesthesia*/veterinary , Blood Pressure Monitors*/veterinary, Animals ; Female ; Male ; Prospective Studies |
| Abstract: | Objective: To evaluate the agreement of the PetMAP noninvasive blood pressure (NIBP) device with digital cuff and the Mindray NIBP device with wrist cuff with invasive blood pressure (IBP) in bonobos. Study Design: Prospective clinical study (non-blinded or -randomized). Animals: A group of 12 bonobos aged 5-44 years undergoing anaesthesia for enclosure movement and health checks. Methods: Systolic (SAP), diastolic (DAP) and mean (MAP) arterial pressure measurements were recorded simultaneously at 5-minute intervals using the NIBP devices and IBP via anterior tibial artery cannulation. Modified Bland-Altman and adapted error grid analyses assessed agreement between IBP and NIBP and the clinical implications of any biases respectively. A 95% limit of agreement (LOA) estimated the possible magnitude of sampling error. Pearson r correlations between IBP and NIBP measurements were calculated. A p < 0.05 was considered significant. Results: IBP ranges were SAP 50-137 mmHg, MAP 32-85 mmHg and DAP 20-69 mmHg. Biases with the PetMAP were -6.8 mmHg for SAP (LOA -41.3 to 27.7 mmHg), -7.2 mmHg for MAP (LOA -30.7 to 16.3 mmHg) and -3.1 mmHg for DAP (LOA -25.5 to 19.3 mmHg) from 84 PetMAP-IBP paired measurements. Correlation coefficients were 0.6 for SAP and DAP and 0.7 for MAP. Whilst 70% of MAP values were clinically acceptable, 13% demonstrated unrecognised hypotension. The Mindray demonstrated biases of -25.3 mmHg for SAP (LOA -69.5 to 18.9 mmHg), -17.5 mmHg for MAP (LOA -51.4 to 16.5 mmHg) and -14.4 mmHg for DAP (LOA -42.2 to 13.5 mmHg) from 95 Mindray-IBP paired measurements. Correlation coefficients were 0.7 for all. Only 45% of MAP values were clinically acceptable and 26% demonstrated unrecognised hypotension. Conclusions and Clinical Relevance: Whilst the PetMAP agreed more closely with IBP, neither device met all the American College of Veterinary Internal Medicine validation criteria, and neither should be used to identify hypotension. (Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved.) |
| Competing Interests: | Conflict of interest statement The authors declare no conflict of interest. |
| Contributed Indexing: | Keywords: ape; bonobo; cardiovascular; invasive blood pressure; noninvasive blood pressure; validation |
| Entry Date(s): | Date Created: 20251206 Date Completed: 20260506 Latest Revision: 20260506 |
| Update Code: | 20260507 |
| DOI: | 10.1016/j.vaa.2025.10.009 |
| PMID: | 41353007 |
| Database: | MEDLINE |
| ISSN: | 1467-2995 |
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| DOI: | 10.1016/j.vaa.2025.10.009 |