Academic Journal
Effect of butorphanol in combination with xylazine during castration of calves: A randomised trial under field conditions.
| Τίτλος: | Effect of butorphanol in combination with xylazine during castration of calves: A randomised trial under field conditions. |
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| Συγγραφείς: | Sannö A; Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences, Uppsala, Sweden., Snygg L; Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences, Uppsala, Sweden., Wiklund M; Evidensia Specialistdjursjukhuset Stromsholm, Stromsholm, Sweden., Nyman G; Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences, Uppsala, Sweden. |
| Πηγή: | The Veterinary record [Vet Rec] 2026 Sep 19; Vol. 199 (6), pp. e298-e303. Date of Electronic Publication: 2025 Dec 02. |
| Τύπος έκδοσης: | Journal Article; Randomized Controlled Trial, Veterinary |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Wiley Country of Publication: England NLM ID: 0031164 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2042-7670 (Electronic) Linking ISSN: 00424900 NLM ISO Abbreviation: Vet Rec Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2021- : [Oxford] : Wiley Original Publication: -June 2009 : London : British Veterinary Medicine |
| Ιατρικοί όροι (MeSH): | Analgesics, Opioid*/administration & dosage , Butorphanol*/administration & dosage , Butorphanol*/pharmacology , Orchiectomy*/veterinary , Orchiectomy*/methods , Xylazine*/administration & dosage , Xylazine*/pharmacology, Cattle/surgery ; Vocalization, Animal/drug effects ; Animals ; Male ; Drug Therapy, Combination |
| Περίληψη: | Background: In horses, cats and dogs, the opioid butorphanol has been proven effective in management of visceral pain and for peri- and postoperative pain relief. The aim of this study was to evaluate physiological responses and indicators of noxious stimuli when adding butorphanol to xylazine for sedation of bull calves during surgical castration. Methods: In total, 54 bull calves were randomly assigned to a control group sedated with only xylazine and a treatment group sedated with the addition of butorphanol prior to castration. Observation of physiological responses by blinded observers from sedation and 1 hour onwards. Results: Apart from significantly more vocalisations in the treatment group prior, during and after the surgical procedure, no adverse effects of butorphanol addition were noted. Also, improved alertness and less drowsiness 1 hour after initiation of sedation were seen in the treatment group possibly associated with improved analgesia. Limitations: A longer follow-up time after sedation and additional measurements of cortisol levels would have given additional valuable information CONCLUSION: Addition of butorphanol leads to increased vocalisation during and possibly a shortened recovery time post-sedation. (© 2025 The Author(s). Veterinary Record published by John Wiley & Sons Ltd on behalf of British Veterinary Association.) |
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| Substance Nomenclature: | 0 (Analgesics, Opioid) QV897JC36D (Butorphanol) 2KFG9TP5V8 (Xylazine) |
| Entry Date(s): | Date Created: 20251202 Date Completed: 20260918 Latest Revision: 20260930 |
| Update Code: | 20261001 |
| PubMed Central ID: | PMC13587254 |
| DOI: | 10.1002/vetr.6017 |
| PMID: | 41328727 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 2042-7670 |
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| DOI: | 10.1002/vetr.6017 |