Synthesis, characterization, and antimicrobial activity of a β‑AgVO₃ coating applied to dental acrylic resin.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Synthesis, characterization, and antimicrobial activity of a β‑AgVO₃ coating applied to dental acrylic resin.
Συγγραφείς: Kreve S; Department of Dental Materials and Prosthesis, Ribeirão Preto Dental School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil. Electronic address: simonek@alumni.usp.br., Ferreira I; Department of Dental Materials and Prosthesis, Ribeirão Preto Dental School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil. Electronic address: izabela.ferreira@usp.br., Carvalho-Silva JM; Department of Dental Materials and Prosthesis, Ribeirão Preto Dental School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil. Electronic address: joaomarcoscs@usp.br., Uehara LM; Department of Dental Materials and Prosthesis, Ribeirão Preto Dental School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil. Electronic address: liuehara@usp.br., Schiavon MA; Department of Natural Sciences, Federal University of São João Del-Rei, São João Del-Rei, MG, Brazil. Electronic address: schiavon@ufsj.edu.br., Reis ACD; Department of Dental Materials and Prosthesis, Ribeirão Preto Dental School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil. Electronic address: andreare@forp.usp.br.
Πηγή: Journal of dentistry [J Dent] 2026 Jan; Vol. 164, pp. 106227. Date of Electronic Publication: 2025 Nov 08.
Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Elsevier Country of Publication: England NLM ID: 0354422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-176X (Electronic) Linking ISSN: 03005712 NLM ISO Abbreviation: J Dent Subsets: MEDLINE
Imprint Name(s): Publication: Kidlington : Elsevier
Original Publication: Bristol, Eng., Wright.
Ιατρικοί όροι (MeSH): Acrylic Resins*/chemistry , Anti-Infective Agents*/pharmacology , Vanadates*/chemistry , Vanadates*/pharmacology , Silver*/chemistry , Silver*/pharmacology, Nanostructures/chemistry ; Polymethyl Methacrylate/chemistry ; Biofilms/drug effects ; Coated Materials, Biocompatible/chemistry ; Coated Materials, Biocompatible/pharmacology ; Microbial Sensitivity Tests ; Mechanical Phenomena ; Surface Properties ; Materials Testing ; Silver Compounds
Περίληψη: Objectives: This study developed an antimicrobial polymer coating of β‑AgVO₃ on acrylic resin disks to prevent denture stomatitis and other oral microbial infections.
Methods: The nanomaterial was synthesized by precipitation reaction between silver nitrate (AgNO₃) and ammonium metavanadate (NH₄VO₃). The minimum inhibitory concentration (MIC) was assessed against S. mutans, C. albicans, C. glabrata, S. aureus, and P. aeruginosa. Disks (Ø 9 mm × 2 mm) made of self-curing acrylic resin (SC) and heat-curing acrylic resin (HC) were created, with eight groups established based on MIC concentration: SCC, SC-MIC, SC-5MIC, SC-10MIC, HCC, HC-MIC, HC-5MIC, and HC-10MIC. Physical characterization of surface topography, chemical composition, chemical interaction, Ag and V release, wettability, roughness, hardness, and color change was conducted. Antimicrobial activity was evaluated by colony‑forming unit counts (CFU) and metabolic activity quantification (XTT) in two multispecies biofilm models.
Results: The specimens were coated with β-AgVO3, and FTIR and SEM/EDS analyses confirmed the presence of the material. Results for color change, roughness, wettability, and hardness indicated unsatisfactory coating performance. Additionally, ionic release tests showed low ion concentrations, in agreement with the absence of antimicrobial activity observed.
Conclusion: Under the evaluated conditions, the coating methodology employed was not effective for antimicrobial purposes.
Clinical Significance: Under the evaluated conditions, the technique is not viable for preventing denture stomatitis or other oral infections associated with biofilms on acrylic prostheses.
(Copyright © 2025 Elsevier Ltd. All rights reserved.)
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Contributed Indexing: Keywords: Antibacterial coating; Dental acrylic resin; Dental biomaterials; Denture stomatitis; Silver vanadate
Substance Nomenclature: 0 (Acrylic Resins)
0 (Anti-Infective Agents)
0 (silver vanadate)
3WHH0066W5 (Vanadates)
3M4G523W1G (Silver)
9011-14-7 (Polymethyl Methacrylate)
0 (Coated Materials, Biocompatible)
0 (Silver Compounds)
Entry Date(s): Date Created: 20251110 Date Completed: 20260417 Latest Revision: 20260616
Update Code: 20260617
DOI: 10.1016/j.jdent.2025.106227
PMID: 41213423
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1879-176X
DOI:10.1016/j.jdent.2025.106227