Academic Journal
Intraoperative perforating vessel injury as a key risk factor for esophageal fistula formation following endoscopic resection of giant esophageal submucosal tumors.
| Τίτλος: | Intraoperative perforating vessel injury as a key risk factor for esophageal fistula formation following endoscopic resection of giant esophageal submucosal tumors. |
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| Συγγραφείς: | Geng ZH; Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China., Zhang SY; Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China., Qin WZ; Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China., Qu YF; Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China., Fu PY; Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China., Zhu Y; Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China., Shou HK; Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China., Huang L; Department of Gastroenterology, Affiliated Maternity and Child Healthcare Hospital of Nantong University, Nantong, Jiangsu, China., Jiang ZB; Gastroenterology and Endoscopy Center, Puning Overseas Chinese Hospital, Guangdong, China., Chen JN; Gastroenterology and Endoscopy Center, Henan Province Puyang People's Hospital, Henan, China., Ren Z; Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China., Li QL; Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China., Zhou PH; Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China., Liu JZ; Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China. |
| Πηγή: | International journal of surgery (London, England) [Int J Surg] 2025 Nov 05. Date of Electronic Publication: 2025 Nov 05. |
| Publication Model: | Ahead of Print |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 101228232 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1743-9159 (Electronic) Linking ISSN: 17439159 NLM ISO Abbreviation: Int J Surg Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2023- : [Philadelphia] : Wolters Kluwer Health, Inc. Original Publication: London : Surgical Associates Ltd., c2004- |
| Περίληψη: | Background and Aim: Endoscopic resection (ER) has been successfully used to remove giant esophageal submucosal tumors (SMTs). However, though rare, esophageal fistula can also develop after endoscopic resection. The aim of this study was to evaluate risk factors for fistula formation after ER of giant esophageal SMTs. Methods: This retrospective study enrolled patients with huge esophageal SMTs who underwent ER. We collected patient demographics, lesion-related factors, and procedural outcomes data and explored the correlation between esophageal fistula formation and damage to perforating vessels. Results: Of 174 patients, 17 (9.8%) had esophageal fistula. The multivariate analysis demonstrated that perforating vessel damage and full-thickness muscular injury were significant risk factors for esophageal fistula. Then, we used a scoring system to predict esophageal fistula and categorized patients into low-risk (0-2) and high-risk (3-6) groups. Patients with high scores were more likely to suffer esophageal fistula. Our score model presented excellent discriminatory power in the internal validation (AUC: 0.932; 95% CI: 0.797-1.000) and goodness-of-fit in the Hosmer-Lemeshow test (p = 0.748). Conclusions: Fistula formation after ER of giant esophageal SMTs is associated with damage to perforating vessels. (Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.) |
| Contributed Indexing: | Keywords: endoscopic resection; fistula; giant esophageal submucosal tumors; perforating vessels |
| Entry Date(s): | Date Created: 20251105 Latest Revision: 20251105 |
| Update Code: | 20260130 |
| DOI: | 10.1097/JS9.0000000000003716 |
| PMID: | 41190347 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1743-9159 |
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| DOI: | 10.1097/JS9.0000000000003716 |