Adherence to Animal Research: Reporting of In Vivo Experiments Guidelines in Stem Cell Studies in Animal Models of Parkinson's Disease: A Systematic Review.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος:	Adherence to Animal Research: Reporting of In Vivo Experiments Guidelines in Stem Cell Studies in Animal Models of Parkinson's Disease: A Systematic Review.
Συγγραφείς:	Park JM; Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea., Sung BK; Yonsei University Wonju College of Medicine, Wonju, Korea., Myung JY; Chungnam National University College of Medicine, Daejeon, Korea., Lee SC; Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea., Yon DK; Center for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, Seoul, Korea., Shin JI; Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.; The Center for Medical Education Training and Professional Development in Yonsei-Donggok Medical Education Institute, Seoul, Korea.; Severance Underwood Meta-research Center, Institute of Convergence Science, Yonsei University, Seoul, Korea. shinji@yuhs.ac., Kim YW; Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea. ywkim1@yuhs.ac., Ioannidis JPA; Department of Medicine, Department of Epidemiology and Population Health and Department of Biomedical Data Science, and Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford, USA.
Πηγή:	Yonsei medical journal [Yonsei Med J] 2025 Nov; Vol. 66 (11), pp. 743-752.
Τύπος έκδοσης:	Journal Article; Systematic Review
Γλώσσα:	English
Στοιχεία περιοδικού:	Publisher: Yonsei University Country of Publication: Korea (South) NLM ID: 0414003 Publication Model: Print Cited Medium: Internet ISSN: 1976-2437 (Electronic) Linking ISSN: 05135796 NLM ISO Abbreviation: Yonsei Med J Subsets: MEDLINE
Imprint Name(s):	Original Publication: Seoul : Yonsei University
Ιατρικοί όροι (MeSH):	Parkinson Disease/therapy , Animal Experimentation/standards , Stem Cell Research/ethics , Guideline Adherence, Research Design/standards ; Animals ; Disease Models, Animal ; Humans ; Guidelines as Topic
Περίληψη:	Purpose: The Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines were published in 2010 and revised in 2020 to improve the reporting of preclinical animal studies. The present study evaluated the reporting of animal stem cell research related to Parkinson's disease (PD). Materials and Methods: Articles on this topic published up to October 18, 2024, were systematically searched in relevant databases. For each individual study, we analyzed the proportion of subsets that were reported, partially reported, or unreported for each of the 38 ARRIVE 2.0 items. We compared reporting before and after the publication of the ARRIVE guidelines, and analyzed compliance score changes over time and by country. Results: We analyzed 90 animal studies related to PD. None of the studies reported sample size calculations, adverse event reporting, or humane endpoints. Additionally, only about 20% or less of the studies reported on strategies to minimize potential confounders, inclusion or exclusion of animal conditions, limitations, allocation methods, and pre-protocol enrollment. We observed no substantial improvement in adherence after publication of the guidelines or over time. Conclusion: The reporting of key design principles in animal stem cell research related to PD was insufficient both before and after the introduction of the ARRIVE guidelines in 2010. Both researchers and journal editors should pay more attention to the accurate, comprehensive reporting of animal studies. (© Copyright: Yonsei University College of Medicine 2025.)
Competing Interests:	The authors have no potential conflicts of interest to disclose.
References:	Biochem Med (Zagreb). 2012;22(3):276-82. (PMID: 23092060) Lab Anim. 2024 Apr;58(2):109-115. (PMID: 37728936) Neurochem Int. 2008 Jun;52(7):1332-42. (PMID: 18372079) Animals (Basel). 2021 Aug 21;11(8):. (PMID: 34438913) Yonsei Med J. 1986;27(1):49-53. (PMID: 3604272) PLoS Negl Trop Dis. 2015 Nov 20;9(11):e0004194. (PMID: 26587586) J Cereb Blood Flow Metab. 2011 Apr;31(4):1064-72. (PMID: 21157472) Br J Pharmacol. 2010 Aug;160(7):1577-9. (PMID: 20649561) Vet Clin Pathol. 2012 Mar;41(1):27-31. (PMID: 22390425) BMC Med Res Methodol. 2006 Mar 13;6:10. (PMID: 16533396) Exp Neurol. 2008 Mar;210(1):14-29. (PMID: 18061169) Yonsei Med J. 2018 May;59(3):406-415. (PMID: 29611403) Nat Hum Behav. 2018 Jan;2(1):6-10. (PMID: 30980045) Lab Anim. 2011 Oct;45(4):225-30. (PMID: 21737463) Cardiovasc Diagn Ther. 2024 Dec 31;14(6):1070-1082. (PMID: 39790189) PLoS Med. 2005 Aug;2(8):e124. (PMID: 16060722) JAMA. 2006 Oct 11;296(14):1731-2. (PMID: 17032985) J Neurol. 2005 Sep;252(9):1108-14. (PMID: 16170651) Gastroenterol Hepatol Bed Bench. 2013 Winter;6(1):14-7. (PMID: 24834239) Comp Med. 2023 Dec 1;73(6):446-460. (PMID: 38217069) J Am Vet Med Assoc. 2016 Nov 1;249(9):1079-1087. (PMID: 27767430) Support Care Cancer. 2021 Nov;29(11):7073-7084. (PMID: 34080055) Popul Dev Rev. 2019 Mar;45(1):219-233. (PMID: 31007310) Hernia. 2022 Apr;26(2):389-400. (PMID: 33394255) PLoS Biol. 2020 Jul 14;18(7):e3000410. (PMID: 32663219) J Pharmacol Pharmacother. 2013 Oct;4(4):303-6. (PMID: 24250214) Nat Neurosci. 1998 Aug;1(4):290-5. (PMID: 10195162) PLoS One. 2018 May 24;13(5):e0197882. (PMID: 29795636) J Neural Transm Suppl. 2007;(72):133-43. (PMID: 17982886) BMJ Open Sci. 2018 Jun 12;2(1):e000002. (PMID: 33954268)
Grant Information:	Korea Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine; Korea Yonsei Fellowship
Contributed Indexing:	Keywords: ARRIVE guidelines; Parkinson's disease; animal experimentation; guideline adherence; quality control; stem cell research
Entry Date(s):	Date Created: 20251027 Date Completed: 20251027 Latest Revision: 20251102
Update Code:	20260130
PubMed Central ID:	PMC12568442
DOI:	10.3349/ymj.2024.0409
PMID:	41145309
Βάση Δεδομένων:	MEDLINE

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ISSN:	1976-2437
DOI:	10.3349/ymj.2024.0409