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Photoacoustic Microscopy Imaging and Region-Specific Segmentation of Ileocecal Malignant Tumor and Mixed Hemorrhoid Tissue Sections.

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Τίτλος: Photoacoustic Microscopy Imaging and Region-Specific Segmentation of Ileocecal Malignant Tumor and Mixed Hemorrhoid Tissue Sections.
Συγγραφείς: Wang X; Academy of Artificial Intelligence, Beijing Institute of Petrochemical Technology, Beijing, China., Cai M; Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, China., Mu R; Academy of Artificial Intelligence, Beijing Institute of Petrochemical Technology, Beijing, China., Liu C; Academy of Artificial Intelligence, Beijing Institute of Petrochemical Technology, Beijing, China., Han Y; Academy of Artificial Intelligence, Beijing Institute of Petrochemical Technology, Beijing, China., Xie Z; Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, China., Li D; Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, China., An X; Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, China., Li J; China-Japan Friendship Hospital, Beijing, China., Niu C; Academy of Artificial Intelligence, Beijing Institute of Petrochemical Technology, Beijing, China., Yang Q; Academy of Artificial Intelligence, Beijing Institute of Petrochemical Technology, Beijing, China., Liu Q; Academy of Artificial Intelligence, Beijing Institute of Petrochemical Technology, Beijing, China.
Πηγή: Journal of biophotonics [J Biophotonics] 2026 Feb; Vol. 19 (2), pp. e202500169. Date of Electronic Publication: 2025 Oct 09.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101318567 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1864-0648 (Electronic) Linking ISSN: 1864063X NLM ISO Abbreviation: J Biophotonics Subsets: MEDLINE
Imprint Name(s): Original Publication: Weinheim : Wiley-VCH
Ιατρικοί όροι (MeSH): Hemorrhoids*/diagnostic imaging , Hemorrhoids*/pathology , Microscopy*/methods , Ileal Neoplasms*/diagnostic imaging , Ileal Neoplasms*/pathology , Cecal Neoplasms*/diagnostic imaging , Cecal Neoplasms*/pathology , Photoacoustic Techniques* , Image Processing, Computer-Assisted*, Humans ; Animals
Περίληψη: The sensitivity of the photoacoustic effect to hemoglobin and structural features in biological tissues has led to its wide application in biomedical research, including vascular imaging and tumor tissue detection. In this study, we customed an optical-resolution photoacoustic microscopy system to analyze tissue sections derived from mixed hemorrhoids and ileocecal malignant tumors. Experimental results show that photoacoustic microscopy system accurately captures tissue morphology, revealing the edges and microvessel networks in mixed hemorrhoids and the irregular boundaries and mass-like structures in ileocecal tumors. Furthermore, this study employed a morphological approach to quantitatively analyze specific regional features in colorectal tissue images. Experimental results demonstrate that photoacoustic microscopy can accurately capture the boundaries in hemorrhoid regions, providing clinical guidance for assessing hemorrhoid types. It can also distinguish ileocecal tumor tissue from healthy ileocecal tissue based on tumor boundary characteristics, showing significant potential to improve both clinical diagnostic accuracy and surgical resection efficiency.
(© 2025 Wiley‐VCH GmbH.)
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Grant Information: 22019821001 Beijing Municipal Education Commission; 2023015 Zhiyuan Science Foundation; BIPTAAI-2021-004 Climbing Program Foundation; Beijing Institute of Petrochemical Technology; 2024J00025 Undergraduate Research Training (URT) Project of Beijing institute of petrochemical technology; 2024J00027 Undergraduate Research Training (URT) Project of Beijing institute of petrochemical technology
Contributed Indexing: Keywords: computational analysis; ileocecal malignant tumor; mixed hemorrhoid; photoacoustic imaging
Entry Date(s): Date Created: 20251009 Date Completed: 20260204 Latest Revision: 20260204
Update Code: 20260205
DOI: 10.1002/jbio.202500169
PMID: 41065136
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1864-0648
DOI:10.1002/jbio.202500169