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Space Impacts Temporal Processing via a Visual-Dependent Spatially Organized Neural Architecture.

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Τίτλος: Space Impacts Temporal Processing via a Visual-Dependent Spatially Organized Neural Architecture.
Συγγραφείς: Amadeo MB; Unit for Visually Impaired People (U-VIP), Istituto Italiano di Tecnologia, Genoa 16152, Italy mariabianca.amadeo@iit.it., Cuppini C; Department of Electrical, Electronic, and Information Engineering 'Guglielmo Marconi', University of Bologna, Bologna 40126, Italy., Tonelli A; Unit for Visually Impaired People (U-VIP), Istituto Italiano di Tecnologia, Genoa 16152, Italy.; School of Psychology, The University of Sydney, Sydney 2006, Australia., Tammurello C; Unit for Visually Impaired People (U-VIP), Istituto Italiano di Tecnologia, Genoa 16152, Italy.; Department of Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS), Università degli Studi di Genova, Genoa 16145, Italy., Setti W; Unit for Visually Impaired People (U-VIP), Istituto Italiano di Tecnologia, Genoa 16152, Italy., Campus C; Unit for Visually Impaired People (U-VIP), Istituto Italiano di Tecnologia, Genoa 16152, Italy., Signorini S; Developmental Neurophthalmology Unit, IRCCS Mondino Foundation, Pavia 27100, Italy., Cocchi E; Fondazione Chiossone, Genova, Italy., Bonino M; Scientific Institute, IRCCS E. Medea, Lecco 23849, Bosisio Parini, Italy., Tinelli F; Department of Developmental Neuroscience, IRCCS Fondazione Stella Maris, Pisa 56128, Italy., Camicione P; IRCCS Istituto Giannina Gaslini, Genova 16147, Italy., Serafino M; IRCCS Istituto Giannina Gaslini, Genova 16147, Italy., Gori M; Unit for Visually Impaired People (U-VIP), Istituto Italiano di Tecnologia, Genoa 16152, Italy.
Πηγή: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2026 Jan 07; Vol. 46 (1). Date of Electronic Publication: 2026 Jan 07.
Τύπος έκδοσης: Journal Article; Research Support, Non-U.S. Gov't
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE
Imprint Name(s): Publication: Washington, DC : Society for Neuroscience
Original Publication: [Baltimore, Md.] : The Society, c1981-
Ιατρικοί όροι (MeSH): Space Perception*/physiology , Time Perception*/physiology , Visual Perception*/physiology, Blindness/physiopathology ; Photic Stimulation/methods ; Humans ; Female ; Male ; Adult ; Child ; Young Adult ; Adolescent ; Middle Aged ; Acoustic Stimulation
Περίληψη: Establishing the temporal relationship between stimuli challenges the brain, requiring some tolerance for asynchronies to form coherent representations. Based on the theory of implicit causal inference, we hypothesized that temporal processing of events is influenced by spatial features as stimuli coming from the same spatial location are most likely to derive from a common source and, consequently, implicitly merged in time. As visual experience guides the formation of neural sensory maps, we expected the spatial influence on temporal processing to depend on visual experience. In Experiment 1, 41 sighted children and adults (22 females) judged the temporal order of auditory and tactile stimuli delivered to the same or different hands (somatotopic manipulation), with hands either close or far apart (spatiotopic manipulation). In Experiment 2, sighted individuals (15 females) were compared with 26 early blind children and adults (12 females) during the somatotopic manipulation with hands far apart. Results revealed an improvement of temporal resolution with age in sighted individuals, while blind children performed similarly to adults. Notably, spatial features affected the temporal processing of sighted but not blind people, regardless of age. Sighted participants showed higher temporal tolerance toward asynchronies in the case of somatotopic or spatiotopic congruence. A bioinspired neurocomputational model has been developed to unveil neural mechanisms underlying the interaction between spatial and temporal processing. The model demonstrates that temporal processing is mediated by a spatially organized synaptic architecture, which requires visual experience to develop. Without vision, spatial alignment may not be conceptualized as a prior influencing temporal processing.
(Copyright © 2025 Amadeo et al.)
Competing Interests: The authors declare no competing financial interests.
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Contributed Indexing: Keywords: auditory–tactile; blindness; neural modeling; spatial perception; temporal perception
Entry Date(s): Date Created: 20251008 Date Completed: 20260107 Latest Revision: 20260630
Update Code: 20260701
PubMed Central ID: PMC12782747
DOI: 10.1523/JNEUROSCI.1444-24.2025
PMID: 41062282
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1529-2401
DOI:10.1523/JNEUROSCI.1444-24.2025